Click here to switch to the map view.

The map label for this gene is acuC [H]

Identifier: 23099678

GI number: 23099678

Start: 2261351

End: 2262538

Strand: Direct

Name: acuC [H]

Synonym: OB2223

Alternate gene names: 23099678

Gene position: 2261351-2262538 (Clockwise)

Preceding gene: 23099677

Following gene: 23099683

Centisome position: 62.29

GC content: 36.03

Gene sequence:

>1188_bases
ATGACTGGTACTTCAGGTTTTGTATATTCAGCCGATTATTTGAAATACCACTTTCACGAAAACCATCCATTTAATCAAAA
AAGAGTGCTTTTAACGAAAGAGTTATTGGAAGCTCATCAAGTATTAAGTAATCATGATTTAATATCTCCTCGATTGGCCA
CTGAGGAAGAATTATTATTATTTCATCATCCTAACTATATGGAAACAGTCAAACGAGCTGGAAGTGGAGAAATTACAGAA
GAAAGTGCTTTAGAGTATGGAATAGGAACAGAGGACACCCCTGCTTTTTTTCAAATGCATGAGGCAGCTAGCTATTTAGT
AGGCGGTACATTAGCAGCAGTTGATGCTGTATTAAATAATAATTATACACATGCATTAAACCTAGGAGGGGGACTGCATC
ATGGTTTTAGAAGTCGTGCCTCCGGATTTTGTATATATAATGATAGCGCAGTAGCTATAAAATATATTCGCAAACATACC
AATTTTAAAGTTCTTTATGTTGACACAGACGCACATCATGGGGACGGGGTTCAATCTGCATTTTATGATGATCCAAATGT
ATGTACTTTCTCCATCCATGAAACTGGTAGATATTTATTTCCCGGAACAGGTAATATAAACGAACGCGGTATTAAAGAAG
GCCATGGTTATACCTTTAATTTACCGATTGATGCGTTCACGCAGGATGAATCATTTTTAGCATTATATGAAACCGCATTC
AAAGAAATTGCTGCTTTTTTTAAACCAGATATTATTGTTACTCAAAATGGAGTAGACGCTCATTGCTTGGATCCACTCAC
TCATTTATGTGGAACGATGCGTATATTTGAAGAGATTCCTCGAATCGCCCATGAACTTGCTCATGAATATTGTGACGGTA
AATGGATTGCTATAGGTGGTGGCGGCTATGATATGTGGAGAGTAATCCCTAGAGCCTGGGGACAAATATGGAATGTAATG
AAAAACAATAAAGTTAGTTATGGTGAATTGCCTACAACATGGTTAGAAAAATGGCAAGAGCAATCATCCGTTGAACTACC
CCACTTATGGCAAGATCTTGAGGATATTCAACCATATATTCCTAGGAAGGATGAAATTACAGAGAAAAATTATCAGTTAC
TACAAAGTCTATTAAAATATACAAAACCGATAAATTATTCAAATAATTTATCGGCAAAGCAAAAGTAA

Upstream 100 bases:

>100_bases
TATTTCGTGTAAAAACATTAAATCCCATGCCGATCATACAAGACTTACGAGAAGCTGGATATCCATTATTGTGGCCAAAT
AATATTGCGGAGCCGAAACG

Downstream 100 bases:

>100_bases
AATTAGTTCACAATTAAAGGGGGGCATGCTCTCCCCCCTTTCTGTTTGTGAGAAAACAAGATATCTACGAGCCGTCTATC
TTTACTCTATCTTTTTTTCT

Product: acetoin utilization protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTGTSGFVYSADYLKYHFHENHPFNQKRVLLTKELLEAHQVLSNHDLISPRLATEEELLLFHHPNYMETVKRAGSGEITE
ESALEYGIGTEDTPAFFQMHEAASYLVGGTLAAVDAVLNNNYTHALNLGGGLHHGFRSRASGFCIYNDSAVAIKYIRKHT
NFKVLYVDTDAHHGDGVQSAFYDDPNVCTFSIHETGRYLFPGTGNINERGIKEGHGYTFNLPIDAFTQDESFLALYETAF
KEIAAFFKPDIIVTQNGVDAHCLDPLTHLCGTMRIFEEIPRIAHELAHEYCDGKWIAIGGGGYDMWRVIPRAWGQIWNVM
KNNKVSYGELPTTWLEKWQEQSSVELPHLWQDLEDIQPYIPRKDEITEKNYQLLQSLLKYTKPINYSNNLSAKQK

Sequences:

>Translated_395_residues
MTGTSGFVYSADYLKYHFHENHPFNQKRVLLTKELLEAHQVLSNHDLISPRLATEEELLLFHHPNYMETVKRAGSGEITE
ESALEYGIGTEDTPAFFQMHEAASYLVGGTLAAVDAVLNNNYTHALNLGGGLHHGFRSRASGFCIYNDSAVAIKYIRKHT
NFKVLYVDTDAHHGDGVQSAFYDDPNVCTFSIHETGRYLFPGTGNINERGIKEGHGYTFNLPIDAFTQDESFLALYETAF
KEIAAFFKPDIIVTQNGVDAHCLDPLTHLCGTMRIFEEIPRIAHELAHEYCDGKWIAIGGGGYDMWRVIPRAWGQIWNVM
KNNKVSYGELPTTWLEKWQEQSSVELPHLWQDLEDIQPYIPRKDEITEKNYQLLQSLLKYTKPINYSNNLSAKQK
>Mature_394_residues
TGTSGFVYSADYLKYHFHENHPFNQKRVLLTKELLEAHQVLSNHDLISPRLATEEELLLFHHPNYMETVKRAGSGEITEE
SALEYGIGTEDTPAFFQMHEAASYLVGGTLAAVDAVLNNNYTHALNLGGGLHHGFRSRASGFCIYNDSAVAIKYIRKHTN
FKVLYVDTDAHHGDGVQSAFYDDPNVCTFSIHETGRYLFPGTGNINERGIKEGHGYTFNLPIDAFTQDESFLALYETAFK
EIAAFFKPDIIVTQNGVDAHCLDPLTHLCGTMRIFEEIPRIAHELAHEYCDGKWIAIGGGGYDMWRVIPRAWGQIWNVMK
NNKVSYGELPTTWLEKWQEQSSVELPHLWQDLEDIQPYIPRKDEITEKNYQLLQSLLKYTKPINYSNNLSAKQK

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=336, Percent_Identity=30.6547619047619, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI8923769, Length=330, Percent_Identity=30, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI13128860, Length=312, Percent_Identity=31.0897435897436, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI293336691, Length=262, Percent_Identity=32.4427480916031, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI262073092, Length=232, Percent_Identity=31.8965517241379, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI262073088, Length=213, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI20070354, Length=320, Percent_Identity=29.375, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI17158039, Length=240, Percent_Identity=32.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI30795204, Length=240, Percent_Identity=32.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI30795202, Length=240, Percent_Identity=32.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI13128864, Length=382, Percent_Identity=27.7486910994764, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI153085395, Length=289, Percent_Identity=29.757785467128, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI148539870, Length=289, Percent_Identity=26.9896193771626, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI169234807, Length=289, Percent_Identity=26.9896193771626, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226529806, Length=184, Percent_Identity=36.9565217391304, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI62750347, Length=339, Percent_Identity=29.7935103244838, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI62750349, Length=339, Percent_Identity=29.7935103244838, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI217272877, Length=244, Percent_Identity=27.4590163934426, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI209862883, Length=240, Percent_Identity=25.8333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=331, Percent_Identity=32.3262839879154, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17534739, Length=337, Percent_Identity=30.5637982195846, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17561978, Length=328, Percent_Identity=30.4878048780488, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193209491, Length=272, Percent_Identity=30.5147058823529, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17540334, Length=321, Percent_Identity=28.6604361370716, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17540332, Length=321, Percent_Identity=28.0373831775701, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI193206283, Length=321, Percent_Identity=28.0373831775701, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI193207430, Length=294, Percent_Identity=25.1700680272109, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25154020, Length=351, Percent_Identity=23.3618233618234, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17537347, Length=246, Percent_Identity=27.2357723577236, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25154022, Length=349, Percent_Identity=23.7822349570201, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=306, Percent_Identity=31.3725490196078, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323999, Length=333, Percent_Identity=29.7297297297297, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6325325, Length=213, Percent_Identity=29.1079812206573, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324307, Length=316, Percent_Identity=26.2658227848101, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644244, Length=333, Percent_Identity=29.4294294294294, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24657891, Length=309, Percent_Identity=30.42071197411, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281360899, Length=391, Percent_Identity=27.8772378516624, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24642146, Length=391, Percent_Identity=27.8772378516624, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24642142, Length=391, Percent_Identity=27.8772378516624, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24642144, Length=391, Percent_Identity=27.8772378516624, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24641720, Length=187, Percent_Identity=33.6898395721925, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360801, Length=187, Percent_Identity=33.6898395721925, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360799, Length=188, Percent_Identity=32.4468085106383, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24649807, Length=257, Percent_Identity=26.0700389105058, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 44926; Mature: 44795

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTSGFVYSADYLKYHFHENHPFNQKRVLLTKELLEAHQVLSNHDLISPRLATEEELLL
CCCCCCEEEEEHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
FHHPNYMETVKRAGSGEITEESALEYGIGTEDTPAFFQMHEAASYLVGGTLAAVDAVLNN
EECCCHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NYTHALNLGGGLHHGFRSRASGFCIYNDSAVAIKYIRKHTNFKVLYVDTDAHHGDGVQSA
CCEEEEECCCCHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHH
FYDDPNVCTFSIHETGRYLFPGTGNINERGIKEGHGYTFNLPIDAFTQDESFLALYETAF
HCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
KEIAAFFKPDIIVTQNGVDAHCLDPLTHLCGTMRIFEEIPRIAHELAHEYCDGKWIAIGG
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGYDMWRVIPRAWGQIWNVMKNNKVSYGELPTTWLEKWQEQSSVELPHLWQDLEDIQPYI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PRKDEITEKNYQLLQSLLKYTKPINYSNNLSAKQK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGTSGFVYSADYLKYHFHENHPFNQKRVLLTKELLEAHQVLSNHDLISPRLATEEELLL
CCCCCEEEEEHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
FHHPNYMETVKRAGSGEITEESALEYGIGTEDTPAFFQMHEAASYLVGGTLAAVDAVLNN
EECCCHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NYTHALNLGGGLHHGFRSRASGFCIYNDSAVAIKYIRKHTNFKVLYVDTDAHHGDGVQSA
CCEEEEECCCCHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHH
FYDDPNVCTFSIHETGRYLFPGTGNINERGIKEGHGYTFNLPIDAFTQDESFLALYETAF
HCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
KEIAAFFKPDIIVTQNGVDAHCLDPLTHLCGTMRIFEEIPRIAHELAHEYCDGKWIAIGG
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGYDMWRVIPRAWGQIWNVMKNNKVSYGELPTTWLEKWQEQSSVELPHLWQDLEDIQPYI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PRKDEITEKNYQLLQSLLKYTKPINYSNNLSAKQK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]