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The map label for this gene is ykvY [H]

Identifier: 23099642

GI number: 23099642

Start: 2222451

End: 2223548

Strand: Direct

Name: ykvY [H]

Synonym: OB2187

Alternate gene names: 23099642

Gene position: 2222451-2223548 (Clockwise)

Preceding gene: 23099637

Following gene: 23099645

Centisome position: 61.22

GC content: 35.06

Gene sequence:

>1098_bases
ATGCAAGAGCGTTTAGAAAATTTTTTAAATAAGTTAAAGGAACAAACTATAGATAGCGCATTCATAACATCAAAAGCCAA
TGTCTATTATTTGAGTAATTATTATACTGAACCACATGAAAGAATTGTAGGAATCTATCTATCAGAAAACTTTGACCCTA
TTTTCTTATTACCAAAAATGGAAGAAAGCGATGCTAGGAATGCTGGATGGAAGTATACTATCTTAAGTTATTATGATCAC
GAAAATCCTTGGGAGATACTTAAAGATTACTTGAACAAACAAAATCATCAACCACAGTCGGTTGCATTAGAACAAGATCA
TATAACAATGGATCGTTACCAAGCGATCCAAAACACATTACCAGAAGCTCAATTTCAAGACGCCAAAGAGATACTTGCAC
AGTTACGTGTGATTAAATCAGATAAAGAGCTTTCTTTATTAAAAACAGCTGCAGAACTTGCAGATTTCGGTATTCAAACT
GGTGTAGAAACGATTCAAGAAGGCATATCTGAATTAGACCTAGTAGCTACGATCGAATATTCTTTAAAAAAACAAGGGAT
TAGAGAAATGTCATTTCAAACAATGGCTTTATCCGGCGCGAAAACAGCTTCACCACATGGACATCCATCCACTTCTAAAT
TAGAGAAAAACGGATTCGTTCTTTTTGATTTAGGCGTTATTTATCAAGGATATTGCTCGGATATAACGAGAACTGTCGCT
TTTGGAAACTTAACGGAAGAACAAAAAAATGTTTATGAAACCGTATTAAACGCAGAAGAAGCAGCAATCGAAAAATCAGT
GGTTGGAACCTCCGTTGGTGTCATAGATCAAACAGCAAGAAAAGTAATTAATGATGCTGGTTATGGCGAATACTTCACCC
ATCGTATTGGCCACGGATTAGGTATCGAAACACATGAATATCCGTCCATGCACGGAGAAAATAATTTACCTTTACAAAGT
GGCATGACATTTACAATTGAGCCTGGTATTTATGTACCTAATGTTGGTGGAGTACGAATTGAGGATATGATTCATATGAC
TGAAGAAGGACCAAAAACATTAACTAAATATCCGAAAAACCTACAAATAGTGAATTAA

Upstream 100 bases:

>100_bases
TTGTTTCTCTATTCCTAAAAATAGTGAATTACTTCGTCATCTTTTAAAAAATTCTAATATCCTGTTATAATATCAAAATA
CGGAAAGAGGAGGTAATTAA

Downstream 100 bases:

>100_bases
ACAGTTACGTTAAAAAACCGGCCTCGCGAAAATGCAAGGTCGGTTTTTTAACAGCATTTTTTCTGCTAGCCAATAATGCT
AATTACATCACGATACTCCA

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MQERLENFLNKLKEQTIDSAFITSKANVYYLSNYYTEPHERIVGIYLSENFDPIFLLPKMEESDARNAGWKYTILSYYDH
ENPWEILKDYLNKQNHQPQSVALEQDHITMDRYQAIQNTLPEAQFQDAKEILAQLRVIKSDKELSLLKTAAELADFGIQT
GVETIQEGISELDLVATIEYSLKKQGIREMSFQTMALSGAKTASPHGHPSTSKLEKNGFVLFDLGVIYQGYCSDITRTVA
FGNLTEEQKNVYETVLNAEEAAIEKSVVGTSVGVIDQTARKVINDAGYGEYFTHRIGHGLGIETHEYPSMHGENNLPLQS
GMTFTIEPGIYVPNVGGVRIEDMIHMTEEGPKTLTKYPKNLQIVN

Sequences:

>Translated_365_residues
MQERLENFLNKLKEQTIDSAFITSKANVYYLSNYYTEPHERIVGIYLSENFDPIFLLPKMEESDARNAGWKYTILSYYDH
ENPWEILKDYLNKQNHQPQSVALEQDHITMDRYQAIQNTLPEAQFQDAKEILAQLRVIKSDKELSLLKTAAELADFGIQT
GVETIQEGISELDLVATIEYSLKKQGIREMSFQTMALSGAKTASPHGHPSTSKLEKNGFVLFDLGVIYQGYCSDITRTVA
FGNLTEEQKNVYETVLNAEEAAIEKSVVGTSVGVIDQTARKVINDAGYGEYFTHRIGHGLGIETHEYPSMHGENNLPLQS
GMTFTIEPGIYVPNVGGVRIEDMIHMTEEGPKTLTKYPKNLQIVN
>Mature_365_residues
MQERLENFLNKLKEQTIDSAFITSKANVYYLSNYYTEPHERIVGIYLSENFDPIFLLPKMEESDARNAGWKYTILSYYDH
ENPWEILKDYLNKQNHQPQSVALEQDHITMDRYQAIQNTLPEAQFQDAKEILAQLRVIKSDKELSLLKTAAELADFGIQT
GVETIQEGISELDLVATIEYSLKKQGIREMSFQTMALSGAKTASPHGHPSTSKLEKNGFVLFDLGVIYQGYCSDITRTVA
FGNLTEEQKNVYETVLNAEEAAIEKSVVGTSVGVIDQTARKVINDAGYGEYFTHRIGHGLGIETHEYPSMHGENNLPLQS
GMTFTIEPGIYVPNVGGVRIEDMIHMTEEGPKTLTKYPKNLQIVN

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=29.1187739463602, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI149589008, Length=294, Percent_Identity=25.1700680272109, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI260593665, Length=294, Percent_Identity=25.1700680272109, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI93141226, Length=177, Percent_Identity=34.4632768361582, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI264681563, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40385867, Length=246, Percent_Identity=25.2032520325203, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI264681565, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788728, Length=369, Percent_Identity=33.0623306233062, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789275, Length=272, Percent_Identity=27.2058823529412, Blast_Score=111, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17508215, Length=299, Percent_Identity=25.0836120401338, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=373, Percent_Identity=24.3967828418231, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320922, Length=262, Percent_Identity=25.5725190839695, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=24.0282685512367, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19920384, Length=274, Percent_Identity=27.007299270073, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357079, Length=296, Percent_Identity=26.3513513513513, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137632, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 41216; Mature: 41216

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQERLENFLNKLKEQTIDSAFITSKANVYYLSNYYTEPHERIVGIYLSENFDPIFLLPKM
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEECCCCEEEEEECC
EESDARNAGWKYTILSYYDHENPWEILKDYLNKQNHQPQSVALEQDHITMDRYQAIQNTL
CCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHCC
PEAQFQDAKEILAQLRVIKSDKELSLLKTAAELADFGIQTGVETIQEGISELDLVATIEY
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKKQGIREMSFQTMALSGAKTASPHGHPSTSKLEKNGFVLFDLGVIYQGYCSDITRTVA
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHCCCCEEEEEHHHHHHHHHHHHHHHHH
FGNLTEEQKNVYETVLNAEEAAIEKSVVGTSVGVIDQTARKVINDAGYGEYFTHRIGHGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
GIETHEYPSMHGENNLPLQSGMTFTIEPGIYVPNVGGVRIEDMIHMTEEGPKTLTKYPKN
CCCCCCCCCCCCCCCCCHHCCCEEEECCCEEECCCCCEEHHHHHHHHCCCCHHHHHCCCC
LQIVN
CEECC
>Mature Secondary Structure
MQERLENFLNKLKEQTIDSAFITSKANVYYLSNYYTEPHERIVGIYLSENFDPIFLLPKM
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEECCCCEEEEEECC
EESDARNAGWKYTILSYYDHENPWEILKDYLNKQNHQPQSVALEQDHITMDRYQAIQNTL
CCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHCC
PEAQFQDAKEILAQLRVIKSDKELSLLKTAAELADFGIQTGVETIQEGISELDLVATIEY
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKKQGIREMSFQTMALSGAKTASPHGHPSTSKLEKNGFVLFDLGVIYQGYCSDITRTVA
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHCCCCEEEEEHHHHHHHHHHHHHHHHH
FGNLTEEQKNVYETVLNAEEAAIEKSVVGTSVGVIDQTARKVINDAGYGEYFTHRIGHGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
GIETHEYPSMHGENNLPLQSGMTFTIEPGIYVPNVGGVRIEDMIHMTEEGPKTLTKYPKN
CCCCCCCCCCCCCCCCCHHCCCEEEECCCEEECCCCCEEHHHHHHHHCCCCHHHHHCCCC
LQIVN
CEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]