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The map label for this gene is yqgF [H]

Identifier: 23099385

GI number: 23099385

Start: 1955069

End: 1957153

Strand: Reverse

Name: yqgF [H]

Synonym: OB1930

Alternate gene names: 23099385

Gene position: 1957153-1955069 (Counterclockwise)

Preceding gene: 23099386

Following gene: 23099384

Centisome position: 53.91

GC content: 35.68

Gene sequence:

>2085_bases
TTGAGTAAAGATATTAAAAAGAAACGAGCCCAACTTCCCTTTCGGATAAATATATTATTTTTTGCAATCTTTTTGATGTT
CTCTGTATTAATTTTGCAATTAGGGGTTGTTCAAATATTAAATGGGGAGGCTCACCAAGAAGAAATTGAGAGAACCAATA
TTGATACGACAAGTGTACCGGTCCCAAGAGGAAGAATCTTGGATACTAATGGAAATGTAATTGTAGATAATAATGCAATG
TATTCTATTACGTATACACCACCAAAAGGGGTACAAGCTAAAGACCGCTTACAATTAGCCCAAAAGTTAGCGGATTATAT
TGAGATGGGTCAGGAAGATCGCTTAAAACGTATCACAGATAGAGATAAACGAGAATATTATTACTTATTAAATCAAAAAG
ATGTAGACGAACGGTTAAATGACATAGATACTTCCGAAATGGATAATGCAGATGTATATAACCACACATTAGAGTTGATT
ACCGAGGAAGAAATCAGTGATTTTTCTGATGACGATATGGAAATTATCGCCATAAAAAAAGAATTAGATAAAGCATATTC
ATTGACTCCACAAGTTATAAAGAATGAAGATGTATCAGCTGAGGAATATGCTACTGTAGCGGAGAATCTTGATAAATTAC
CAGGAATAAATGCGACAACAGATTGGGATCGACTGTATCCTTATGATAATACGCTAAGCAGTATCCTGGGAGGTATTACA
AGTCAAGAGCAGGGTATTCCAGCTGAAGATGTGCAGGCATACTTAAGTAAAGGATATAGCCGTAATGATCGAGTAGGTAC
AAGTGGAATAGAACAACAATATGAGGATTTCCTGCGAGGAAGAAAAGAACAGATTCAATATGAGACAAGAAAAAATGGAT
CAATAGTTGGAACGGAAACAGTAGTTGAAGGGAAACGAGGAAAAGACCTTGTATTAACTATTGATATGGAATTTCAGGAA
AAAGTAGATGAAATAGTATTAGATGAAATGAAGAAGGTTAAACAACAATATCCTGGACCTAACCAACACTTAACCAATGC
ATTCGCAGTAGTAATGGATCCAAAAACAGGAGAACTACTGGCGATGTCTGGTGTGAATTATAATAAAGAAAAAAACGAAT
ACAATGATGCTGCATTTATGGCTTTAGCTAGCGCATATGAACCTGGATCATCCGTAAAAGGTGCCAGTGTATTAGCAGGG
TATGAATCAGGTGTCATTTCACCTGGTCAAGTTTTTTTTGATAACCCCGTTAGGATAGCTAGTACGCCTGTAAAAAAATC
AGTTTCAAATTTAGGCTATGTAACAGATCTAGAAGCATTGGAAAAATCTTCAAACGTATATATGTTTTATATTGCTTTAA
GAATGATGGGAGAAAATCGTCACCCTTATCCAGATAACTCAACTCTTAATGCAAGTTGGTCTGAATACAACAATGCGCTA
AATGATTTACAAAATTACTTTAATCAATTTGGTCTAGGAGTATCTACAGGTATTGATTTTCCACATGAATCTACCGGGGT
TAGATCAAATGGTGCACCGAACCCAGGTAATGTTCTGGACTTTACAATAGGACAATATGATACGTATACGACATTACAGT
TAGCACAATATGTTTCAACAATTGCCAATGATGGATATCGTGTTCAACCACACTTTTTAAAGCAAGTTCATGATCCGATT
GCATCATTTGATGAATTAGGTCCAGTGTATTATACAAAAAATACGCAAGTAATGAACCGTATTGATATGAGTCAAAGTGA
AATAGAACGAGTACAAAATGGTTTTAAGCGAGTTTATGAATCTGGAACAGCAAGAGGTTATTTTCAAGATGTAGATTATA
ATCCTGCAGGTAAGACAGGAACAGCTGAAACATCTATTTATGATGATGGGAAAAAGCTAGCTGATACAAATAGTCTTTCA
CTTGTTGGCTATGCTCCATTTGATGAACCTGAAGTTGCATTTGCCATAATAGTTCCACACACGGGGCAAGGAAATGGAAT
TAACGGTAAAATCGGCAGACGTATCCTCGATGCATACTTCGAAGTCAAAGAAGAACAAGATGAAGAAAATGCAGTTGATG
AATAA

Upstream 100 bases:

>100_bases
ATTTTAATAAAAGAGCAAATTACAGACGAAAAAAATCGTTAATTATGGTAAAATCAAACAGAGGAAAATATTGTACTAAA
TTATTGGGGGAGAAGAAACA

Downstream 100 bases:

>100_bases
AAAATAAGCGAATCCAAAATGGATTCGCTTATTTTTATAAATGATTACATAGAATTTACAAATAGTTAATATTAAACCTT
TATAATTAGTAACATATAGA

Product: penicillin-binding protein 2A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MSKDIKKKRAQLPFRINILFFAIFLMFSVLILQLGVVQILNGEAHQEEIERTNIDTTSVPVPRGRILDTNGNVIVDNNAM
YSITYTPPKGVQAKDRLQLAQKLADYIEMGQEDRLKRITDRDKREYYYLLNQKDVDERLNDIDTSEMDNADVYNHTLELI
TEEEISDFSDDDMEIIAIKKELDKAYSLTPQVIKNEDVSAEEYATVAENLDKLPGINATTDWDRLYPYDNTLSSILGGIT
SQEQGIPAEDVQAYLSKGYSRNDRVGTSGIEQQYEDFLRGRKEQIQYETRKNGSIVGTETVVEGKRGKDLVLTIDMEFQE
KVDEIVLDEMKKVKQQYPGPNQHLTNAFAVVMDPKTGELLAMSGVNYNKEKNEYNDAAFMALASAYEPGSSVKGASVLAG
YESGVISPGQVFFDNPVRIASTPVKKSVSNLGYVTDLEALEKSSNVYMFYIALRMMGENRHPYPDNSTLNASWSEYNNAL
NDLQNYFNQFGLGVSTGIDFPHESTGVRSNGAPNPGNVLDFTIGQYDTYTTLQLAQYVSTIANDGYRVQPHFLKQVHDPI
ASFDELGPVYYTKNTQVMNRIDMSQSEIERVQNGFKRVYESGTARGYFQDVDYNPAGKTGTAETSIYDDGKKLADTNSLS
LVGYAPFDEPEVAFAIIVPHTGQGNGINGKIGRRILDAYFEVKEEQDEENAVDE

Sequences:

>Translated_694_residues
MSKDIKKKRAQLPFRINILFFAIFLMFSVLILQLGVVQILNGEAHQEEIERTNIDTTSVPVPRGRILDTNGNVIVDNNAM
YSITYTPPKGVQAKDRLQLAQKLADYIEMGQEDRLKRITDRDKREYYYLLNQKDVDERLNDIDTSEMDNADVYNHTLELI
TEEEISDFSDDDMEIIAIKKELDKAYSLTPQVIKNEDVSAEEYATVAENLDKLPGINATTDWDRLYPYDNTLSSILGGIT
SQEQGIPAEDVQAYLSKGYSRNDRVGTSGIEQQYEDFLRGRKEQIQYETRKNGSIVGTETVVEGKRGKDLVLTIDMEFQE
KVDEIVLDEMKKVKQQYPGPNQHLTNAFAVVMDPKTGELLAMSGVNYNKEKNEYNDAAFMALASAYEPGSSVKGASVLAG
YESGVISPGQVFFDNPVRIASTPVKKSVSNLGYVTDLEALEKSSNVYMFYIALRMMGENRHPYPDNSTLNASWSEYNNAL
NDLQNYFNQFGLGVSTGIDFPHESTGVRSNGAPNPGNVLDFTIGQYDTYTTLQLAQYVSTIANDGYRVQPHFLKQVHDPI
ASFDELGPVYYTKNTQVMNRIDMSQSEIERVQNGFKRVYESGTARGYFQDVDYNPAGKTGTAETSIYDDGKKLADTNSLS
LVGYAPFDEPEVAFAIIVPHTGQGNGINGKIGRRILDAYFEVKEEQDEENAVDE
>Mature_693_residues
SKDIKKKRAQLPFRINILFFAIFLMFSVLILQLGVVQILNGEAHQEEIERTNIDTTSVPVPRGRILDTNGNVIVDNNAMY
SITYTPPKGVQAKDRLQLAQKLADYIEMGQEDRLKRITDRDKREYYYLLNQKDVDERLNDIDTSEMDNADVYNHTLELIT
EEEISDFSDDDMEIIAIKKELDKAYSLTPQVIKNEDVSAEEYATVAENLDKLPGINATTDWDRLYPYDNTLSSILGGITS
QEQGIPAEDVQAYLSKGYSRNDRVGTSGIEQQYEDFLRGRKEQIQYETRKNGSIVGTETVVEGKRGKDLVLTIDMEFQEK
VDEIVLDEMKKVKQQYPGPNQHLTNAFAVVMDPKTGELLAMSGVNYNKEKNEYNDAAFMALASAYEPGSSVKGASVLAGY
ESGVISPGQVFFDNPVRIASTPVKKSVSNLGYVTDLEALEKSSNVYMFYIALRMMGENRHPYPDNSTLNASWSEYNNALN
DLQNYFNQFGLGVSTGIDFPHESTGVRSNGAPNPGNVLDFTIGQYDTYTTLQLAQYVSTIANDGYRVQPHFLKQVHDPIA
SFDELGPVYYTKNTQVMNRIDMSQSEIERVQNGFKRVYESGTARGYFQDVDYNPAGKTGTAETSIYDDGKKLADTNSLSL
VGYAPFDEPEVAFAIIVPHTGQGNGINGKIGRRILDAYFEVKEEQDEENAVDE

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=635, Percent_Identity=24.251968503937, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786272, Length=464, Percent_Identity=23.9224137931034, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 77921; Mature: 77789

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDIKKKRAQLPFRINILFFAIFLMFSVLILQLGVVQILNGEAHQEEIERTNIDTTSVP
CCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCC
VPRGRILDTNGNVIVDNNAMYSITYTPPKGVQAKDRLQLAQKLADYIEMGQEDRLKRITD
CCCCEEEECCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
RDKREYYYLLNQKDVDERLNDIDTSEMDNADVYNHTLELITEEEISDFSDDDMEIIAIKK
CCCCEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
ELDKAYSLTPQVIKNEDVSAEEYATVAENLDKLPGINATTDWDRLYPYDNTLSSILGGIT
HHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHCCCC
SQEQGIPAEDVQAYLSKGYSRNDRVGTSGIEQQYEDFLRGRKEQIQYETRKNGSIVGTET
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECHH
VVEGKRGKDLVLTIDMEFQEKVDEIVLDEMKKVKQQYPGPNQHLTNAFAVVMDPKTGELL
HCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEEECCCCCCEE
AMSGVNYNKEKNEYNDAAFMALASAYEPGSSVKGASVLAGYESGVISPGQVFFDNPVRIA
EECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCEEECCCEEEE
STPVKKSVSNLGYVTDLEALEKSSNVYMFYIALRMMGENRHPYPDNSTLNASWSEYNNAL
CCCHHHHHHHCCCHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHH
NDLQNYFNQFGLGVSTGIDFPHESTGVRSNGAPNPGNVLDFTIGQYDTYTTLQLAQYVST
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
IANDGYRVQPHFLKQVHDPIASFDELGPVYYTKNTQVMNRIDMSQSEIERVQNGFKRVYE
HHCCCEEECHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHH
SGTARGYFQDVDYNPAGKTGTAETSIYDDGKKLADTNSLSLVGYAPFDEPEVAFAIIVPH
CCCCCCEEECCCCCCCCCCCCCCCCEECCCCHHCCCCCEEEEEECCCCCCCEEEEEEEEC
TGQGNGINGKIGRRILDAYFEVKEEQDEENAVDE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKDIKKKRAQLPFRINILFFAIFLMFSVLILQLGVVQILNGEAHQEEIERTNIDTTSVP
CCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCC
VPRGRILDTNGNVIVDNNAMYSITYTPPKGVQAKDRLQLAQKLADYIEMGQEDRLKRITD
CCCCEEEECCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
RDKREYYYLLNQKDVDERLNDIDTSEMDNADVYNHTLELITEEEISDFSDDDMEIIAIKK
CCCCEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
ELDKAYSLTPQVIKNEDVSAEEYATVAENLDKLPGINATTDWDRLYPYDNTLSSILGGIT
HHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHCCCC
SQEQGIPAEDVQAYLSKGYSRNDRVGTSGIEQQYEDFLRGRKEQIQYETRKNGSIVGTET
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECHH
VVEGKRGKDLVLTIDMEFQEKVDEIVLDEMKKVKQQYPGPNQHLTNAFAVVMDPKTGELL
HCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEEECCCCCCEE
AMSGVNYNKEKNEYNDAAFMALASAYEPGSSVKGASVLAGYESGVISPGQVFFDNPVRIA
EECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCEEECCCEEEE
STPVKKSVSNLGYVTDLEALEKSSNVYMFYIALRMMGENRHPYPDNSTLNASWSEYNNAL
CCCHHHHHHHCCCHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHHH
NDLQNYFNQFGLGVSTGIDFPHESTGVRSNGAPNPGNVLDFTIGQYDTYTTLQLAQYVST
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
IANDGYRVQPHFLKQVHDPIASFDELGPVYYTKNTQVMNRIDMSQSEIERVQNGFKRVYE
HHCCCEEECHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHH
SGTARGYFQDVDYNPAGKTGTAETSIYDDGKKLADTNSLSLVGYAPFDEPEVAFAIIVPH
CCCCCCEEECCCCCCCCCCCCCCCCEECCCCHHCCCCCEEEEEECCCCCCCEEEEEEEEC
TGQGNGINGKIGRRILDAYFEVKEEQDEENAVDE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]