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The map label for this gene is yqgN [H]

Identifier: 23099379

GI number: 23099379

Start: 1952470

End: 1953030

Strand: Reverse

Name: yqgN [H]

Synonym: OB1924

Alternate gene names: 23099379

Gene position: 1953030-1952470 (Counterclockwise)

Preceding gene: 23099380

Following gene: 23099378

Centisome position: 53.79

GC content: 32.98

Gene sequence:

>561_bases
ATGAATAAGCAAATTTTAAGGAAAAATATGATTCAACAATTAAATGAATTATCTCAAGATAGAAGAAAGTCTATTCAATC
AAAACAACAGCATCTACTATTTCATTCACACCTATGGAAAAATTCCTTAACAATTGGAATCACTGTTTCTAAAGGGTTCG
AATGGGACACGAAACAAATTATTCAACAAGGATGGAAAGAAAATAAAGTAATTGCCGTTCCTAAATGTAATCCGATTGAT
AAAACAATGACATATCGTCAAATCACTTCTTTTGAACAACTTGAAGTTGTATACGCGGGAATTGAAGAGCCTATTATGGA
ACATACGAGTCCCTTAGAAAATGAATTACTTGGATTATGTATTGTTCCGGGAATTGTTTTTGATAAAAACGGTTATCGGA
TTGGATTTGGTGGGGGGTATTATGATCGAATATTACCGAGTATACAAGCTCCTACCTTGTCAATTTGTAGTGAGGTACAA
ATAATTTCTTCCATACCTAAAGAATCCCATGACCTTTCGGTGGATTATCTACTAACTGAAACAAGAATTTATGGTAGCTA
A

Upstream 100 bases:

>100_bases
ACGTCTTAAAAAACACACGTTACATCGTGAAACAAAATAATGTTAGCAAAAAACTCTTATCGTTTGGATAGGAGTTTTTC
TATTATTAGGGGTGTACATA

Downstream 100 bases:

>100_bases
TTTTTCTATGTATAAGTAAATCATTCTAGAAAAAACTATATACATAATAGAGCTAGGAAGGAATGATTTTTTAATGCGTC
CACTTATTTCGATTGCATTA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNKQILRKNMIQQLNELSQDRRKSIQSKQQHLLFHSHLWKNSLTIGITVSKGFEWDTKQIIQQGWKENKVIAVPKCNPID
KTMTYRQITSFEQLEVVYAGIEEPIMEHTSPLENELLGLCIVPGIVFDKNGYRIGFGGGYYDRILPSIQAPTLSICSEVQ
IISSIPKESHDLSVDYLLTETRIYGS

Sequences:

>Translated_186_residues
MNKQILRKNMIQQLNELSQDRRKSIQSKQQHLLFHSHLWKNSLTIGITVSKGFEWDTKQIIQQGWKENKVIAVPKCNPID
KTMTYRQITSFEQLEVVYAGIEEPIMEHTSPLENELLGLCIVPGIVFDKNGYRIGFGGGYYDRILPSIQAPTLSICSEVQ
IISSIPKESHDLSVDYLLTETRIYGS
>Mature_186_residues
MNKQILRKNMIQQLNELSQDRRKSIQSKQQHLLFHSHLWKNSLTIGITVSKGFEWDTKQIIQQGWKENKVIAVPKCNPID
KTMTYRQITSFEQLEVVYAGIEEPIMEHTSPLENELLGLCIVPGIVFDKNGYRIGFGGGYYDRILPSIQAPTLSICSEVQ
IISSIPKESHDLSVDYLLTETRIYGS

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=145, Percent_Identity=25.5172413793103, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 21310; Mature: 21310

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQILRKNMIQQLNELSQDRRKSIQSKQQHLLFHSHLWKNSLTIGITVSKGFEWDTKQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
IQQGWKENKVIAVPKCNPIDKTMTYRQITSFEQLEVVYAGIEEPIMEHTSPLENELLGLC
HHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
IVPGIVFDKNGYRIGFGGGYYDRILPSIQAPTLSICSEVQIISSIPKESHDLSVDYLLTE
HHCCEEECCCCCEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
TRIYGS
EEECCC
>Mature Secondary Structure
MNKQILRKNMIQQLNELSQDRRKSIQSKQQHLLFHSHLWKNSLTIGITVSKGFEWDTKQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
IQQGWKENKVIAVPKCNPIDKTMTYRQITSFEQLEVVYAGIEEPIMEHTSPLENELLGLC
HHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
IVPGIVFDKNGYRIGFGGGYYDRILPSIQAPTLSICSEVQIISSIPKESHDLSVDYLLTE
HHCCEEECCCCCEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
TRIYGS
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]