Click here to switch to the map view.

The map label for this gene is comGA [H]

Identifier: 23099363

GI number: 23099363

Start: 1939243

End: 1940250

Strand: Direct

Name: comGA [H]

Synonym: OB1908

Alternate gene names: 23099363

Gene position: 1939243-1940250 (Clockwise)

Preceding gene: 23099361

Following gene: 23099364

Centisome position: 53.41

GC content: 35.22

Gene sequence:

>1008_bases
ATGAATGAAGTAAAAAAACTTTCTGACTCCCTCATCCATTCTGCAGTCTCATTACAATCTTCAGACATACACTTTTATCC
TTATCCAACACAAACGGAAATCTATTTTCGTATTCACGGAAGACGTACCCTTCATCGAAAGATTTCTTCAAATCAATATC
GATTATTAATTACTTATTATAAGTTTATTTCTGGTATGGATATCGGCGAGTCCAGAATTCCCCAGCATGGTACAATAATC
TGGACAGAAAAATCGAACACTTATTCTTTACGTATCTCTACCCTCCCCCATCATTTACTAGAAAGTATTGCTATTCGAAT
CCATCCACAACAATCTCATCAAATAGAGAAGAAATTATTTCTTTTTCCAAATCAAATCCGTCACATAAAAAAAGAATGGT
TATCAAATCAAGCAGGTATCATTTTACTAACAGGACCAACTGGAAGTGGAAAATCAACCACTTTATACGCTCTATTAGAG
TCCATGCTTGCCGAAAATTCATGTCAAACTATCACACTAGAAGATCCAATTGAAAAAAAGATGGACAATGTATTACAAAT
TCAAATTAATGAGAAAGCTGGCATTTCCTACCACACAGGACTAAAAGCAGCCCTTCGACATGATCCCGATATAATAATGG
TGGGAGAAATTCGTGATCGTAAAACAGCACAATTTGCCCTTGAAGCTGCTTTAACAGGACACCTCGTTTTCAGTACTTTA
CATGCAAAAAATGCTATAGGAACTATTTTTCGCCTAAAAGAAATGGGCTTGAAAGATATTGATCTAGAGCAAAGTCTATT
AGCAATTGGAGCAATCCAGCTACTACCAATTCAATGTAGAGGCAAACAAAGAAGAGCTGCAATTATGGAATTATTAGAAG
GAGAACAGTTAACAGAGGTAATATACAATCAACGGAAACAACTTGAATACCGTTTTACATTTGAATATCTAAGAAAGAAG
GCTTTTGCATATGGCTTTATCTCTAAAGATGATTATCCGACCACATAA

Upstream 100 bases:

>100_bases
CATAAACCATTATTCAAAATATTTTCAAATTCAGGCAGGATATTCACGCGATATGTAGAAGTATATTATAGTCAGAAATT
CTCAGAAAGGAGGTAGATGA

Downstream 100 bases:

>100_bases
GCTATCTTCTAGTAACCAACTTCGTTTTTTACAAATTTTAAGCAGAATGTTATCGAAAGGATTAACCATTTCTGAATCAC
TCGATACCCTTTCTTTCTAT

Product: late competence protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNEVKKLSDSLIHSAVSLQSSDIHFYPYPTQTEIYFRIHGRRTLHRKISSNQYRLLITYYKFISGMDIGESRIPQHGTII
WTEKSNTYSLRISTLPHHLLESIAIRIHPQQSHQIEKKLFLFPNQIRHIKKEWLSNQAGIILLTGPTGSGKSTTLYALLE
SMLAENSCQTITLEDPIEKKMDNVLQIQINEKAGISYHTGLKAALRHDPDIIMVGEIRDRKTAQFALEAALTGHLVFSTL
HAKNAIGTIFRLKEMGLKDIDLEQSLLAIGAIQLLPIQCRGKQRRAAIMELLEGEQLTEVIYNQRKQLEYRFTFEYLRKK
AFAYGFISKDDYPTT

Sequences:

>Translated_335_residues
MNEVKKLSDSLIHSAVSLQSSDIHFYPYPTQTEIYFRIHGRRTLHRKISSNQYRLLITYYKFISGMDIGESRIPQHGTII
WTEKSNTYSLRISTLPHHLLESIAIRIHPQQSHQIEKKLFLFPNQIRHIKKEWLSNQAGIILLTGPTGSGKSTTLYALLE
SMLAENSCQTITLEDPIEKKMDNVLQIQINEKAGISYHTGLKAALRHDPDIIMVGEIRDRKTAQFALEAALTGHLVFSTL
HAKNAIGTIFRLKEMGLKDIDLEQSLLAIGAIQLLPIQCRGKQRRAAIMELLEGEQLTEVIYNQRKQLEYRFTFEYLRKK
AFAYGFISKDDYPTT
>Mature_335_residues
MNEVKKLSDSLIHSAVSLQSSDIHFYPYPTQTEIYFRIHGRRTLHRKISSNQYRLLITYYKFISGMDIGESRIPQHGTII
WTEKSNTYSLRISTLPHHLLESIAIRIHPQQSHQIEKKLFLFPNQIRHIKKEWLSNQAGIILLTGPTGSGKSTTLYALLE
SMLAENSCQTITLEDPIEKKMDNVLQIQINEKAGISYHTGLKAALRHDPDIIMVGEIRDRKTAQFALEAALTGHLVFSTL
HAKNAIGTIFRLKEMGLKDIDLEQSLLAIGAIQLLPIQCRGKQRRAAIMELLEGEQLTEVIYNQRKQLEYRFTFEYLRKK
AFAYGFISKDDYPTT

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=284, Percent_Identity=40.1408450704225, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1786296, Length=278, Percent_Identity=36.3309352517986, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI87082188, Length=154, Percent_Identity=39.6103896103896, Blast_Score=104, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 38454; Mature: 38454

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVKKLSDSLIHSAVSLQSSDIHFYPYPTQTEIYFRIHGRRTLHRKISSNQYRLLITYY
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEECCHHHHHHHCCCCEEEEEEEH
KFISGMDIGESRIPQHGTIIWTEKSNTYSLRISTLPHHLLESIAIRIHPQQSHQIEKKLF
HHHCCCCCCCCCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHHEEEECCCHHHHHHHHHC
LFPNQIRHIKKEWLSNQAGIILLTGPTGSGKSTTLYALLESMLAENSCQTITLEDPIEKK
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHH
MDNVLQIQINEKAGISYHTGLKAALRHDPDIIMVGEIRDRKTAQFALEAALTGHLVFSTL
CCCEEEEEECCCCCCEECCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
HAKNAIGTIFRLKEMGLKDIDLEQSLLAIGAIQLLPIQCRGKQRRAAIMELLEGEQLTEV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCHHHHHH
IYNQRKQLEYRFTFEYLRKKAFAYGFISKDDYPTT
HHHHHHHEEHHHHHHHHHHHHHHEECCCCCCCCCC
>Mature Secondary Structure
MNEVKKLSDSLIHSAVSLQSSDIHFYPYPTQTEIYFRIHGRRTLHRKISSNQYRLLITYY
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEECCHHHHHHHCCCCEEEEEEEH
KFISGMDIGESRIPQHGTIIWTEKSNTYSLRISTLPHHLLESIAIRIHPQQSHQIEKKLF
HHHCCCCCCCCCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHHEEEECCCHHHHHHHHHC
LFPNQIRHIKKEWLSNQAGIILLTGPTGSGKSTTLYALLESMLAENSCQTITLEDPIEKK
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHH
MDNVLQIQINEKAGISYHTGLKAALRHDPDIIMVGEIRDRKTAQFALEAALTGHLVFSTL
CCCEEEEEECCCCCCEECCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
HAKNAIGTIFRLKEMGLKDIDLEQSLLAIGAIQLLPIQCRGKQRRAAIMELLEGEQLTEV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCHHHHHH
IYNQRKQLEYRFTFEYLRKKAFAYGFISKDDYPTT
HHHHHHHEEHHHHHHHHHHHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]