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The map label for this gene is yqhT [H]

Identifier: 23099351

GI number: 23099351

Start: 1927279

End: 1928340

Strand: Reverse

Name: yqhT [H]

Synonym: OB1896

Alternate gene names: 23099351

Gene position: 1928340-1927279 (Counterclockwise)

Preceding gene: 23099352

Following gene: 23099350

Centisome position: 53.11

GC content: 36.63

Gene sequence:

>1062_bases
TTGACTAAAATACAACAATTACGTAGTCGTATGGAAGAACATAATGTTGATGCTATTATAATTAGTAGTCCGTATAATAG
ACGCTATATTACAGGTTTTACTGGGAGCGCCGGTGCTGCTTTGATAACTGGGGATAAAGCAGTATTTATTACTGATTTTA
GATATACCGAACAAGCTTCTGCTCAAGCCTCAGATTTTGATATTGTAGAACATAAAGGTGGCATAGCAAAGGAAGTTAGT
AAATTAATTAGTGAAAATAATATAACCAGATTAGGGTTTGAAAAGGATTATACAACATACGCAGAATATTTATCTTATCA
AGAATCTTTTTCTGCTGAATTAGTTCCCTTTAATGGATGGATTGAAGAATTACGCATGATTAAAACACCAGAAGAATTAG
AAGTGATGAAAAAAGCAGCAGAAATTGCCGATGATGCGTTTGCCCATATTCAGAATTATATTAAACCTGGAGTACCTGAA
ATTGAGATTTCCAATGAATTAGAATTCTTTATGCGTCGTAAAGGAGCAACTTCCTCAAGTTTCGATACTATCGTAGCATC
CGGGCACAGATCTGCTTTACCACATGGTGTTGCGTCTGATAAAAAAATCCAATCTGGTGAGCTTGTTACTTTAGATTATG
GTGCTCTATATAATGGGTATTGTTCCGACATTACCCGAACGGTTGCAGTAGGTGAAATTTCTGTCGAACTTAAGCAAATA
TATGATATAGTATTAGAGGCGAACCTTCGTGGAGTAAAAGGTACGAAACCAGGAATCTCTGGTATAGAAGCTGACAGTCT
CACAAGAGATTATATTACGGAGAAAGGTTATGGTGAACAGTTTGGACATTCTACAGGACATGGACTTGGATTAGAGGTTC
ATGAAGGTCCTGGATTATCTTTTCGTTCTGATATAATTTTGAAACCTGGAATGGTAGTAACCGTAGAACCAGGAATATAT
GTACAAGGACTTGGAGGTTGTCGTATCGAGGATGATATCGTGATCACTGATACAGGAAACGAGCGATTAACTTTTGCTCC
AAAAGAATTGATTCAGCTTTAA

Upstream 100 bases:

>100_bases
CCAATCAGAAAGCTCCCAATAATTATTCAAACTATTGATTTTGTGTTAAACTAAAATACAAAAATAGATAGTTTTCTGAC
TATATGGGAGGATGAGAGAT

Downstream 100 bases:

>100_bases
AACCCATACATAGGGAGGAACAAAAATGATTTCAGTAAATGATTTTAAAACAGGGCTTACAGTTGAAGTAGACAATGATA
TCTGGCAAGTAATTGAATTT

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTKIQQLRSRMEEHNVDAIIISSPYNRRYITGFTGSAGAALITGDKAVFITDFRYTEQASAQASDFDIVEHKGGIAKEVS
KLISENNITRLGFEKDYTTYAEYLSYQESFSAELVPFNGWIEELRMIKTPEELEVMKKAAEIADDAFAHIQNYIKPGVPE
IEISNELEFFMRRKGATSSSFDTIVASGHRSALPHGVASDKKIQSGELVTLDYGALYNGYCSDITRTVAVGEISVELKQI
YDIVLEANLRGVKGTKPGISGIEADSLTRDYITEKGYGEQFGHSTGHGLGLEVHEGPGLSFRSDIILKPGMVVTVEPGIY
VQGLGGCRIEDDIVITDTGNERLTFAPKELIQL

Sequences:

>Translated_353_residues
MTKIQQLRSRMEEHNVDAIIISSPYNRRYITGFTGSAGAALITGDKAVFITDFRYTEQASAQASDFDIVEHKGGIAKEVS
KLISENNITRLGFEKDYTTYAEYLSYQESFSAELVPFNGWIEELRMIKTPEELEVMKKAAEIADDAFAHIQNYIKPGVPE
IEISNELEFFMRRKGATSSSFDTIVASGHRSALPHGVASDKKIQSGELVTLDYGALYNGYCSDITRTVAVGEISVELKQI
YDIVLEANLRGVKGTKPGISGIEADSLTRDYITEKGYGEQFGHSTGHGLGLEVHEGPGLSFRSDIILKPGMVVTVEPGIY
VQGLGGCRIEDDIVITDTGNERLTFAPKELIQL
>Mature_352_residues
TKIQQLRSRMEEHNVDAIIISSPYNRRYITGFTGSAGAALITGDKAVFITDFRYTEQASAQASDFDIVEHKGGIAKEVSK
LISENNITRLGFEKDYTTYAEYLSYQESFSAELVPFNGWIEELRMIKTPEELEVMKKAAEIADDAFAHIQNYIKPGVPEI
EISNELEFFMRRKGATSSSFDTIVASGHRSALPHGVASDKKIQSGELVTLDYGALYNGYCSDITRTVAVGEISVELKQIY
DIVLEANLRGVKGTKPGISGIEADSLTRDYITEKGYGEQFGHSTGHGLGLEVHEGPGLSFRSDIILKPGMVVTVEPGIYV
QGLGGCRIEDDIVITDTGNERLTFAPKELIQL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI149589008, Length=291, Percent_Identity=31.6151202749141, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI260593665, Length=291, Percent_Identity=31.6151202749141, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI11559925, Length=260, Percent_Identity=33.8461538461538, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI260593663, Length=302, Percent_Identity=27.4834437086093, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI264681563, Length=251, Percent_Identity=31.4741035856574, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI93141226, Length=169, Percent_Identity=36.094674556213, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI264681565, Length=248, Percent_Identity=30.241935483871, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI164420681, Length=240, Percent_Identity=22.0833333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788728, Length=358, Percent_Identity=43.0167597765363, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1789275, Length=262, Percent_Identity=34.7328244274809, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=25.5905511811024, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790282, Length=283, Percent_Identity=25.7950530035336, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17508215, Length=296, Percent_Identity=29.0540540540541, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17509539, Length=211, Percent_Identity=33.6492890995261, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6321118, Length=302, Percent_Identity=27.4834437086093, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=28.8537549407115, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322999, Length=186, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323273, Length=203, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357079, Length=292, Percent_Identity=30.4794520547945, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI19920384, Length=280, Percent_Identity=31.0714285714286, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137632, Length=373, Percent_Identity=27.3458445040214, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38868; Mature: 38737

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIQQLRSRMEEHNVDAIIISSPYNRRYITGFTGSAGAALITGDKAVFITDFRYTEQAS
CCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCEEEEECCCEEEEEECCCCCCCC
AQASDFDIVEHKGGIAKEVSKLISENNITRLGFEKDYTTYAEYLSYQESFSAELVPFNGW
CCCCCCCHHHCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECHHH
IEELRMIKTPEELEVMKKAAEIADDAFAHIQNYIKPGVPEIEISNELEFFMRRKGATSSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCC
FDTIVASGHRSALPHGVASDKKIQSGELVTLDYGALYNGYCSDITRTVAVGEISVELKQI
CHHHEECCCCCCCCCCCCCCCEECCCCEEEEECCCHHCCHHHHHHHHEEEEHHHHHHHHH
YDIVLEANLRGVKGTKPGISGIEADSLTRDYITEKGYGEQFGHSTGHGLGLEVHEGPGLS
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEECCCCCC
FRSDIILKPGMVVTVEPGIYVQGLGGCRIEDDIVITDTGNERLTFAPKELIQL
CCCCEEECCCEEEEECCCEEEECCCCCEEECCEEEECCCCCEEEECHHHHHCC
>Mature Secondary Structure 
TKIQQLRSRMEEHNVDAIIISSPYNRRYITGFTGSAGAALITGDKAVFITDFRYTEQAS
CHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCEEEEECCCEEEEEECCCCCCCC
AQASDFDIVEHKGGIAKEVSKLISENNITRLGFEKDYTTYAEYLSYQESFSAELVPFNGW
CCCCCCCHHHCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECHHH
IEELRMIKTPEELEVMKKAAEIADDAFAHIQNYIKPGVPEIEISNELEFFMRRKGATSSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCC
FDTIVASGHRSALPHGVASDKKIQSGELVTLDYGALYNGYCSDITRTVAVGEISVELKQI
CHHHEECCCCCCCCCCCCCCCEECCCCEEEEECCCHHCCHHHHHHHHEEEEHHHHHHHHH
YDIVLEANLRGVKGTKPGISGIEADSLTRDYITEKGYGEQFGHSTGHGLGLEVHEGPGLS
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEECCCCCC
FRSDIILKPGMVVTVEPGIYVQGLGGCRIEDDIVITDTGNERLTFAPKELIQL
CCCCEEECCCEEEEECCCEEEECCCCCEEECCEEEECCCCCEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]