Click here to switch to the map view.

The map label for this gene is yqjD [H]

Identifier: 23099315

GI number: 23099315

Start: 1890649

End: 1891926

Strand: Reverse

Name: yqjD [H]

Synonym: OB1860

Alternate gene names: 23099315

Gene position: 1891926-1890649 (Counterclockwise)

Preceding gene: 23099316

Following gene: 23099314

Centisome position: 52.11

GC content: 35.68

Gene sequence:

>1278_bases
GTGGTAGGATATGCAACTATAAGTAAAAAACCAATATATGTGTTTGCTCATGATTTTACAGTGCGTGGAGGTTCATTAGG
TGAATTGCAAGGAAAAAAAATAGCATCCATGATGGATCTAGCAGCAAAGACAAAGGTACCAATTGTTGGATTAAATGAAT
CGGCTGGTGCTCGTATTCAAGAAGGTGTCACTGCGTTAGATGGTTATGGACAAATATTTTATCGTAATGTTAAGTATTCT
GGAGTGATACCACAAATATCTATTATTTTAGGTCCTAATGCCGGTGGAGCAGTATACTCTCCTGCACTCACTGATTTTAT
TATAATGGTGAAGGACATATCGCAAATGTATATTACTGGTCCTAAAGTTATTGAAGCGATTACGAAAGAAACAGTATCTG
CAGAGGATTTAGGCGGAACATATATGCACGCTGTGGTGAATGGTAATTGTCATTTTCTAGCAACAAATGAACAAGAAGCT
TTTCAAATCACAGCAAAACTTCTCACATTTATTAATACAACTACTATGTCAAATGAGTTAACTGCTAGAGATTATTGTAA
TAGTTTACATGAGCTGGTACCGAGTGAATCAGGTAAAACCTACGATGTTATACCAATTATAGAAACAATTGTTGATGACG
GAAGTTTTTTAGAAGTACATAAATATTTTGCCAAAAATATTGTAGTTGGTTTTGCATCACTATTAGGTAAAACGATAGGT
ATTGTATCCAACCAACCGAAACATATGGCTGGAGGAATTGATTCCAATGCAAGTGATAAAGCAGCACGATTTATAAGATT
CTGTGATTGTTTCAACATTCCAATTATAACGCTAGAGGATGTGACTGGATTTTATCCTGGAATACGTTATGAGAAAGAAG
GAATAATACGTCATGGTGCGAAATTAGTTTATGCTTTTGCTGAAGCAACAGTACCTAAAATTACTGTAATACTACGTAAA
GCTTATGGTGGTGCATTTGTGGCGATGAATAGTAAAGCTCTCGGAGCGGACCTGCTATATGCATGGCCAAGTGCAGAAAT
AGCAGTTATGGGTCCAGAAGGCGCTTCTAGTGTTTTTAAAACAGACAAAAAAGATAATGAAACACGAACTAATCTACCAA
ATAATTCAACAAGTCCATATTATGCTGCTGCAAAAGGGATGGTTGATGACATTATTGATCCAAGGGAAACAAGAATCAAA
TTAATACAATCTTTTATTATGCTAGAACAAAAAAATGAAACAGCTCCTATCCGGAAACATGGAAACATTCCACTGTAA

Upstream 100 bases:

>100_bases
AGAAAGAATTGATACATTAGTAGATGAAGGTTCATTTATAGAGCTTTATCCATTTATGAAAAAGTCAGAAGATAGTAATG
ATCCACCAGGGGAAGGGGTA

Downstream 100 bases:

>100_bases
AAAAAGATTATTTTGTAGTAGCCTATAATAGGGAGGTTTTCAATTATGCTAGTAAATGAACAACGATTAGTAGATGAATT
TCTAGAATTAGTACAAGTAG

Product: propionyl-CoA carboxylase beta subunit

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVGYATISKKPIYVFAHDFTVRGGSLGELQGKKIASMMDLAAKTKVPIVGLNESAGARIQEGVTALDGYGQIFYRNVKYS
GVIPQISIILGPNAGGAVYSPALTDFIIMVKDISQMYITGPKVIEAITKETVSAEDLGGTYMHAVVNGNCHFLATNEQEA
FQITAKLLTFINTTTMSNELTARDYCNSLHELVPSESGKTYDVIPIIETIVDDGSFLEVHKYFAKNIVVGFASLLGKTIG
IVSNQPKHMAGGIDSNASDKAARFIRFCDCFNIPIITLEDVTGFYPGIRYEKEGIIRHGAKLVYAFAEATVPKITVILRK
AYGGAFVAMNSKALGADLLYAWPSAEIAVMGPEGASSVFKTDKKDNETRTNLPNNSTSPYYAAAKGMVDDIIDPRETRIK
LIQSFIMLEQKNETAPIRKHGNIPL

Sequences:

>Translated_425_residues
MVGYATISKKPIYVFAHDFTVRGGSLGELQGKKIASMMDLAAKTKVPIVGLNESAGARIQEGVTALDGYGQIFYRNVKYS
GVIPQISIILGPNAGGAVYSPALTDFIIMVKDISQMYITGPKVIEAITKETVSAEDLGGTYMHAVVNGNCHFLATNEQEA
FQITAKLLTFINTTTMSNELTARDYCNSLHELVPSESGKTYDVIPIIETIVDDGSFLEVHKYFAKNIVVGFASLLGKTIG
IVSNQPKHMAGGIDSNASDKAARFIRFCDCFNIPIITLEDVTGFYPGIRYEKEGIIRHGAKLVYAFAEATVPKITVILRK
AYGGAFVAMNSKALGADLLYAWPSAEIAVMGPEGASSVFKTDKKDNETRTNLPNNSTSPYYAAAKGMVDDIIDPRETRIK
LIQSFIMLEQKNETAPIRKHGNIPL
>Mature_425_residues
MVGYATISKKPIYVFAHDFTVRGGSLGELQGKKIASMMDLAAKTKVPIVGLNESAGARIQEGVTALDGYGQIFYRNVKYS
GVIPQISIILGPNAGGAVYSPALTDFIIMVKDISQMYITGPKVIEAITKETVSAEDLGGTYMHAVVNGNCHFLATNEQEA
FQITAKLLTFINTTTMSNELTARDYCNSLHELVPSESGKTYDVIPIIETIVDDGSFLEVHKYFAKNIVVGFASLLGKTIG
IVSNQPKHMAGGIDSNASDKAARFIRFCDCFNIPIITLEDVTGFYPGIRYEKEGIIRHGAKLVYAFAEATVPKITVILRK
AYGGAFVAMNSKALGADLLYAWPSAEIAVMGPEGASSVFKTDKKDNETRTNLPNNSTSPYYAAAKGMVDDIIDPRETRIK
LIQSFIMLEQKNETAPIRKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=436, Percent_Identity=50, Blast_Score=414, Evalue=1e-116,
Organism=Homo sapiens, GI295821216, Length=421, Percent_Identity=50.8313539192399, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI11545863, Length=418, Percent_Identity=32.5358851674641, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI25147359, Length=436, Percent_Identity=50.6880733944954, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI25147362, Length=436, Percent_Identity=50.6880733944954, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17552936, Length=437, Percent_Identity=30.6636155606407, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24586065, Length=440, Percent_Identity=31.1363636363636, Blast_Score=208, Evalue=5e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 46176; Mature: 46176

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGYATISKKPIYVFAHDFTVRGGSLGELQGKKIASMMDLAAKTKVPIVGLNESAGARIQ
CCCCEEECCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHH
EGVTALDGYGQIFYRNVKYSGVIPQISIILGPNAGGAVYSPALTDFIIMVKDISQMYITG
HCCHHHCCCCEEEEEEEEECCCCCEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHCCC
PKVIEAITKETVSAEDLGGTYMHAVVNGNCHFLATNEQEAFQITAKLLTFINTTTMSNEL
HHHHHHHHHHHCCHHHCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
TARDYCNSLHELVPSESGKTYDVIPIIETIVDDGSFLEVHKYFAKNIVVGFASLLGKTIG
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVSNQPKHMAGGIDSNASDKAARFIRFCDCFNIPIITLEDVTGFYPGIRYEKEGIIRHGA
HCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEECCCHHHHCCH
KLVYAFAEATVPKITVILRKAYGGAFVAMNSKALGADLLYAWPSAEIAVMGPEGASSVFK
HHEEEHHHCCCCCEEEEEEHHCCCEEEEECCCCCCCEEEEECCCCCEEEECCCCCHHHHH
TDKKDNETRTNLPNNSTSPYYAAAKGMVDDIIDPRETRIKLIQSFIMLEQKNETAPIRKH
CCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
GNIPL
CCCCC
>Mature Secondary Structure
MVGYATISKKPIYVFAHDFTVRGGSLGELQGKKIASMMDLAAKTKVPIVGLNESAGARIQ
CCCCEEECCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHH
EGVTALDGYGQIFYRNVKYSGVIPQISIILGPNAGGAVYSPALTDFIIMVKDISQMYITG
HCCHHHCCCCEEEEEEEEECCCCCEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHCCC
PKVIEAITKETVSAEDLGGTYMHAVVNGNCHFLATNEQEAFQITAKLLTFINTTTMSNEL
HHHHHHHHHHHCCHHHCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
TARDYCNSLHELVPSESGKTYDVIPIIETIVDDGSFLEVHKYFAKNIVVGFASLLGKTIG
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IVSNQPKHMAGGIDSNASDKAARFIRFCDCFNIPIITLEDVTGFYPGIRYEKEGIIRHGA
HCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEECCCHHHHCCH
KLVYAFAEATVPKITVILRKAYGGAFVAMNSKALGADLLYAWPSAEIAVMGPEGASSVFK
HHEEEHHHCCCCCEEEEEEHHCCCEEEEECCCCCCCEEEEECCCCCEEEECCCCCHHHHH
TDKKDNETRTNLPNNSTSPYYAAAKGMVDDIIDPRETRIKLIQSFIMLEQKNETAPIRKH
CCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
GNIPL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]