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The map label for this gene is fur [H]

Identifier: 23099304

GI number: 23099304

Start: 1880599

End: 1881054

Strand: Reverse

Name: fur [H]

Synonym: OB1849

Alternate gene names: 23099304

Gene position: 1881054-1880599 (Counterclockwise)

Preceding gene: 23099305

Following gene: 23099303

Centisome position: 51.81

GC content: 35.96

Gene sequence:

>456_bases
ATGGAACATCGGATTGACCAAATAAAAAAACAGCTACACTCGCATAGCTATAAATTAACTCCCCAAAGGGAAGCAACGGT
ACGTGTGCTTCTTGAACGAGAAGAAGATCATCTAAGTGCTGAAGATGTTTATTTACTCGTAAAAGAGAAATCACCAGAAA
TAGGGTTGGCTACAGTATATCGTACATTAGAATTGCTTTCGGAGCTAAAAATTGTAGATAAAATTAACTTTGGAGATGGC
GTTTCTCGTTACGATTTACGAAAAGAAGGCGCAAAACATTTTCATCACCATTTAGTATGTATTGAATGTGGATCTGTTGA
AGAAATTGAGAATGATTTATTAGAAGATGTAGAACGTATCGTGCAAACAGACTGGGGATTTGAAGTGAAAGACCATCGGC
TTACTTTTCACGGTATATGTAAACAGTGTCAAGAAGTTATTGTTAAAGCAACTTAA

Upstream 100 bases:

>100_bases
ATTATATTATAATTATTATAATTTAAAAGTGATAATACACTTTGACACGTTGTAATTGGAAGATTATAATATAGTTGGGT
AAAGAGGGAGGCGACTATCC

Downstream 100 bases:

>100_bases
ACTGCCTTTTTCCAATAGGAAAGAGGCAATATTTTTTGTATCATAAATGTATGTAATATTTAGGGTTAGGACAAGCATAT
TCTTTCAATAGAATAATTTA

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MEHRIDQIKKQLHSHSYKLTPQREATVRVLLEREEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLSELKIVDKINFGDG
VSRYDLRKEGAKHFHHHLVCIECGSVEEIENDLLEDVERIVQTDWGFEVKDHRLTFHGICKQCQEVIVKAT

Sequences:

>Translated_151_residues
MEHRIDQIKKQLHSHSYKLTPQREATVRVLLEREEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLSELKIVDKINFGDG
VSRYDLRKEGAKHFHHHLVCIECGSVEEIENDLLEDVERIVQTDWGFEVKDHRLTFHGICKQCQEVIVKAT
>Mature_151_residues
MEHRIDQIKKQLHSHSYKLTPQREATVRVLLEREEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLSELKIVDKINFGDG
VSRYDLRKEGAKHFHHHLVCIECGSVEEIENDLLEDVERIVQTDWGFEVKDHRLTFHGICKQCQEVIVKAT

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=36.9230769230769, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI87082363, Length=142, Percent_Identity=28.8732394366197, Blast_Score=63, Evalue=7e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17615; Mature: 17615

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHRIDQIKKQLHSHSYKLTPQREATVRVLLEREEDHLSAEDVYLLVKEKSPEIGLATVY
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLSELKIVDKINFGDGVSRYDLRKEGAKHFHHHLVCIECGSVEEIENDLLEDVERI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHH
VQTDWGFEVKDHRLTFHGICKQCQEVIVKAT
HHCCCCCCCCCCEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHRIDQIKKQLHSHSYKLTPQREATVRVLLEREEDHLSAEDVYLLVKEKSPEIGLATVY
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLSELKIVDKINFGDGVSRYDLRKEGAKHFHHHLVCIECGSVEEIENDLLEDVERI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHH
VQTDWGFEVKDHRLTFHGICKQCQEVIVKAT
HHCCCCCCCCCCEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]