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The map label for this gene is resD [H]

Identifier: 23099274

GI number: 23099274

Start: 1855402

End: 1856118

Strand: Reverse

Name: resD [H]

Synonym: OB1819

Alternate gene names: 23099274

Gene position: 1856118-1855402 (Counterclockwise)

Preceding gene: 23099275

Following gene: 23099273

Centisome position: 51.13

GC content: 35.43

Gene sequence:

>717_bases
ATGGATATAACACATAAAATACTAGTAGTTGACGATGAAGATAGAATTCGTCGTTTAATAAAAATGTACTTAGAAAAAGA
GGATTTTGAAATAGATGAAGCAGCTGATGGCGATGTTGCTTTGGAAAAAGCGTTAGCGAATGATTATGATGTAATTATTT
TAGATATTATGATGCCTGAAAAAGATGGTATTGAAGTTTGTAAAGAATTACGTAAGGAAAAGGATACACCTGTGATTATG
CTAACTGCTAAAGGCGAAGAATCGAACCGTGTACAAGGGTTTGAGGTTGGAGCTGATGACTATATAGTAAAGCCATTTAG
TCCAAGAGAGGCAGTACTTCGAGTGAAAGCATTACTTCGAAGAGTGTCAACGAAAACCTATCAAGAAGTAGATACATCAT
CTAAAAATATGCTTGTATTCCCACATCTGACGATCGATCATGATGCACACCGAGTCGCAGCGGATAATCAAGAAGTAAGT
TTAACTCCAAAAGAGTATGAACTGTTATGCTTCTTAGCAAACGCACCAGATAAAGTATTTAATAGAGAGCAGTTATTAAA
AGAAGTTTGGCAATATGAATTCTTTGGTGATTTGCGAACTGTAGATACACATGTCAAGAGACTTAGAGAAAAATTAAATA
CAGTTTCTAAAGAAGCTGCCAAAATGATCGTGACGGTTTGGGGTGTAGGATACAAATTTGAGGTAGAAGAAAACTAA

Upstream 100 bases:

>100_bases
AATTATGCGATGATGTGAACATATTATGAACACTTGATTTCTTAACTTTTAATATAGATTCGTTTATAATTTATATAGAT
TGACTTGAGGAGGATTGGCA

Downstream 100 bases:

>100_bases
TGTTTTGGAAAAGTGTAGTTGGTAAGCTGTCATTAACCATTTTACTGTTAGTATCATTTGTTTTATGTGTGCTCACTTTT
TTCCTTATGCAGTTCTTTGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MDITHKILVVDDEDRIRRLIKMYLEKEDFEIDEAADGDVALEKALANDYDVIILDIMMPEKDGIEVCKELRKEKDTPVIM
LTAKGEESNRVQGFEVGADDYIVKPFSPREAVLRVKALLRRVSTKTYQEVDTSSKNMLVFPHLTIDHDAHRVAADNQEVS
LTPKEYELLCFLANAPDKVFNREQLLKEVWQYEFFGDLRTVDTHVKRLREKLNTVSKEAAKMIVTVWGVGYKFEVEEN

Sequences:

>Translated_238_residues
MDITHKILVVDDEDRIRRLIKMYLEKEDFEIDEAADGDVALEKALANDYDVIILDIMMPEKDGIEVCKELRKEKDTPVIM
LTAKGEESNRVQGFEVGADDYIVKPFSPREAVLRVKALLRRVSTKTYQEVDTSSKNMLVFPHLTIDHDAHRVAADNQEVS
LTPKEYELLCFLANAPDKVFNREQLLKEVWQYEFFGDLRTVDTHVKRLREKLNTVSKEAAKMIVTVWGVGYKFEVEEN
>Mature_238_residues
MDITHKILVVDDEDRIRRLIKMYLEKEDFEIDEAADGDVALEKALANDYDVIILDIMMPEKDGIEVCKELRKEKDTPVIM
LTAKGEESNRVQGFEVGADDYIVKPFSPREAVLRVKALLRRVSTKTYQEVDTSSKNMLVFPHLTIDHDAHRVAADNQEVS
LTPKEYELLCFLANAPDKVFNREQLLKEVWQYEFFGDLRTVDTHVKRLREKLNTVSKEAAKMIVTVWGVGYKFEVEEN

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=41.8803418803419, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=40, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=38.1578947368421, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=33.0508474576271, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=238, Percent_Identity=35.7142857142857, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=36.4035087719298, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=38.3259911894273, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=34.2105263157895, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=30.3030303030303, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=31.7391304347826, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=34.7639484978541, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=30.4721030042918, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=31.304347826087, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=26.8398268398268, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788550, Length=243, Percent_Identity=30.4526748971193, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788191, Length=106, Percent_Identity=38.6792452830189, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788713, Length=102, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=189, Percent_Identity=30.1587301587302, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27524; Mature: 27524

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITHKILVVDDEDRIRRLIKMYLEKEDFEIDEAADGDVALEKALANDYDVIILDIMMPE
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCC
KDGIEVCKELRKEKDTPVIMLTAKGEESNRVQGFEVGADDYIVKPFSPREAVLRVKALLR
CCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHH
RVSTKTYQEVDTSSKNMLVFPHLTIDHDAHRVAADNQEVSLTPKEYELLCFLANAPDKVF
HHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHCCCCCEEEECCCCEEEEEEEECCCHHHC
NREQLLKEVWQYEFFGDLRTVDTHVKRLREKLNTVSKEAAKMIVTVWGVGYKFEVEEN
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCC
>Mature Secondary Structure
MDITHKILVVDDEDRIRRLIKMYLEKEDFEIDEAADGDVALEKALANDYDVIILDIMMPE
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCC
KDGIEVCKELRKEKDTPVIMLTAKGEESNRVQGFEVGADDYIVKPFSPREAVLRVKALLR
CCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHH
RVSTKTYQEVDTSSKNMLVFPHLTIDHDAHRVAADNQEVSLTPKEYELLCFLANAPDKVF
HHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHCCCCCEEEECCCCEEEEEEEECCCHHHC
NREQLLKEVWQYEFFGDLRTVDTHVKRLREKLNTVSKEAAKMIVTVWGVGYKFEVEEN
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]