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The map label for this gene is resE [H]

Identifier: 23099273

GI number: 23099273

Start: 1853648

End: 1855402

Strand: Reverse

Name: resE [H]

Synonym: OB1818

Alternate gene names: 23099273

Gene position: 1855402-1853648 (Counterclockwise)

Preceding gene: 23099274

Following gene: 23099272

Centisome position: 51.11

GC content: 34.81

Gene sequence:

>1755_bases
ATGTTTTGGAAAAGTGTAGTTGGTAAGCTGTCATTAACCATTTTACTGTTAGTATCATTTGTTTTATGTGTGCTCACTTT
TTTCCTTATGCAGTTCTTTGATAATTATCATATACAAGAAGCTGAGAATGAAATGGAGCAAATGGCAACAAAAATATCTT
CCCTAGTGGAAACCGATCATGAACAGCCTTTCATTGAAGAAGTTACAGAAATGTTGAAAGATCCCTCTAGTCGAATTGCT
ATTATGTACTCTGAACAAGAAAACTGGATATCAGATAGCAATGATGAGAATCTTCAAGAATTTGACGTTGACTGGATAGA
GGGACAAGAAGAAATTAACACTGTAATTGAAGATAAGCAACAAATTAGTAATCAATTTCATACAGCTAATAATACAGAAG
TAATTCTAGTTGGTGCACCAATAGATGACGGCGGAGCAGTATTTGTTTATAAATCACTAGATATGATTAATCAAACAAAA
GATCAAACGACCAAGCTTATTTTGTTGAGTGCGGGCATTGCAATACTTTTAACTACGTTCTTTGCTGTTTTTTTATCAAC
ACGAATTACTTCGCCTTTAATAAAGATGAAAGAAGCAGCTCATAACTTGACAAGAGGCGAATTTAACACAAAAGTACCTG
TTCTTACACGTGATGAAATTGGTGAACTCGCAATTGAATTTAATCGTATGGGACGGCAATTGAATTATCATATTAATGCG
TTACGTCAGGAAAAAGAGCAACTATCTAGCATTGTAAGTTCTATGGCAGATGGTGTATTTACATTAAATCGTGAAGGGGA
AGTCCTTGTTATTAACCCACCTGCAAAGAAATATATGGATGAATGGTTTTATGAAAATCCCGATGAATCAGAGGGACAGA
ACCATCTACCGACAGAAGTAAAAGAAGCATTACTAGAAGTTATCACAAAAGAATATGCCGTTCTGAAAGAATCTGCAGTA
CAAGGTCGCAGTTATGTAATGCTTGTAACTCCTTTATATGATGAATCCCATGTACGTGGATGTGTTGCAGTAATACGAGA
TATGACGGAGGAAAGAAGGTTAGATAAGTTAAGAAAAGACTTTATTGCTAATGTGTCCCATGAACTTCGTACTCCAATTT
CAATGCTGCAAGGATATAGTGAGGCCATTGTAGATGATGTTGCTAGTTCAAAAGAAGAGAAAAATGAGTTAGCGCAGATT
ATATATGAAGAATCACTAAGAATGGGCAGATTAGTAAATGAATTGCTCGATTTAGCCCGAATGGAGGCAGGTCAAATTCA
ATTACGATTGGATTCTGTAGCAATTCAGCCATTTATTGAAAGAATTGTTCACAAATTCCAAGGTATTTCCCGTGAAGAAA
TGGTCGAATTAGAACTTACAGTAGACATCGAACACCAAATTGGAGAGATGGATCCAGATCGAATCGAACAAGTATTAACA
AATTTAATTGATAATGCAATTCGTCATACCTCTAACAATGGATTTGTAAAAGTTCTTGCTGTAAGTAATCAAGATAAGTT
ATATGTAGAAGTAAAAGATAGCGGTAGTGGTATTCCTGAAGAAGACTTACCGTTTATATTTGAACGATTCTACAAAGCGG
ACAAATCACGAGTCAAAAAAGAAAAACAAGGAACAGGTTTAGGACTGGCAATTGCTAAAAATATCATTGATGCTCATCAT
GGATCAATTTATGTAAAAAGTAAACTAGATGCGGGTACCACATTTAGTTTTGAAATTCCCATTAAACAAAATTAA

Upstream 100 bases:

>100_bases
AGAGACTTAGAGAAAAATTAAATACAGTTTCTAAAGAAGCTGCCAAAATGATCGTGACGGTTTGGGGTGTAGGATACAAA
TTTGAGGTAGAAGAAAACTA

Downstream 100 bases:

>100_bases
TTAGAAAATTATGGTGAAATATTATAACAGTCTAGACCGTGTTATTTTGTTTGGTATCCAAATCAAACGGCGACGTTATG
CAAGCATTGGCTTTCAAGCT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MFWKSVVGKLSLTILLLVSFVLCVLTFFLMQFFDNYHIQEAENEMEQMATKISSLVETDHEQPFIEEVTEMLKDPSSRIA
IMYSEQENWISDSNDENLQEFDVDWIEGQEEINTVIEDKQQISNQFHTANNTEVILVGAPIDDGGAVFVYKSLDMINQTK
DQTTKLILLSAGIAILLTTFFAVFLSTRITSPLIKMKEAAHNLTRGEFNTKVPVLTRDEIGELAIEFNRMGRQLNYHINA
LRQEKEQLSSIVSSMADGVFTLNREGEVLVINPPAKKYMDEWFYENPDESEGQNHLPTEVKEALLEVITKEYAVLKESAV
QGRSYVMLVTPLYDESHVRGCVAVIRDMTEERRLDKLRKDFIANVSHELRTPISMLQGYSEAIVDDVASSKEEKNELAQI
IYEESLRMGRLVNELLDLARMEAGQIQLRLDSVAIQPFIERIVHKFQGISREEMVELELTVDIEHQIGEMDPDRIEQVLT
NLIDNAIRHTSNNGFVKVLAVSNQDKLYVEVKDSGSGIPEEDLPFIFERFYKADKSRVKKEKQGTGLGLAIAKNIIDAHH
GSIYVKSKLDAGTTFSFEIPIKQN

Sequences:

>Translated_584_residues
MFWKSVVGKLSLTILLLVSFVLCVLTFFLMQFFDNYHIQEAENEMEQMATKISSLVETDHEQPFIEEVTEMLKDPSSRIA
IMYSEQENWISDSNDENLQEFDVDWIEGQEEINTVIEDKQQISNQFHTANNTEVILVGAPIDDGGAVFVYKSLDMINQTK
DQTTKLILLSAGIAILLTTFFAVFLSTRITSPLIKMKEAAHNLTRGEFNTKVPVLTRDEIGELAIEFNRMGRQLNYHINA
LRQEKEQLSSIVSSMADGVFTLNREGEVLVINPPAKKYMDEWFYENPDESEGQNHLPTEVKEALLEVITKEYAVLKESAV
QGRSYVMLVTPLYDESHVRGCVAVIRDMTEERRLDKLRKDFIANVSHELRTPISMLQGYSEAIVDDVASSKEEKNELAQI
IYEESLRMGRLVNELLDLARMEAGQIQLRLDSVAIQPFIERIVHKFQGISREEMVELELTVDIEHQIGEMDPDRIEQVLT
NLIDNAIRHTSNNGFVKVLAVSNQDKLYVEVKDSGSGIPEEDLPFIFERFYKADKSRVKKEKQGTGLGLAIAKNIIDAHH
GSIYVKSKLDAGTTFSFEIPIKQN
>Mature_584_residues
MFWKSVVGKLSLTILLLVSFVLCVLTFFLMQFFDNYHIQEAENEMEQMATKISSLVETDHEQPFIEEVTEMLKDPSSRIA
IMYSEQENWISDSNDENLQEFDVDWIEGQEEINTVIEDKQQISNQFHTANNTEVILVGAPIDDGGAVFVYKSLDMINQTK
DQTTKLILLSAGIAILLTTFFAVFLSTRITSPLIKMKEAAHNLTRGEFNTKVPVLTRDEIGELAIEFNRMGRQLNYHINA
LRQEKEQLSSIVSSMADGVFTLNREGEVLVINPPAKKYMDEWFYENPDESEGQNHLPTEVKEALLEVITKEYAVLKESAV
QGRSYVMLVTPLYDESHVRGCVAVIRDMTEERRLDKLRKDFIANVSHELRTPISMLQGYSEAIVDDVASSKEEKNELAQI
IYEESLRMGRLVNELLDLARMEAGQIQLRLDSVAIQPFIERIVHKFQGISREEMVELELTVDIEHQIGEMDPDRIEQVLT
NLIDNAIRHTSNNGFVKVLAVSNQDKLYVEVKDSGSGIPEEDLPFIFERFYKADKSRVKKEKQGTGLGLAIAKNIIDAHH
GSIYVKSKLDAGTTFSFEIPIKQN

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=340, Percent_Identity=30, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=31.6602316602317, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=31.1688311688312, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=30.8695652173913, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=32.0675105485232, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=30.0847457627119, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=29.4871794871795, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=28.0172413793103, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=31.7180616740088, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=28.2700421940928, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=24.0105540897098, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=29.0748898678414, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=28.310502283105, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789808, Length=251, Percent_Identity=25.0996015936255, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=203, Percent_Identity=30.0492610837438, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=28.3950617283951, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790300, Length=287, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787374, Length=249, Percent_Identity=26.1044176706827, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789403, Length=214, Percent_Identity=27.1028037383178, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66515; Mature: 66515

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWKSVVGKLSLTILLLVSFVLCVLTFFLMQFFDNYHIQEAENEMEQMATKISSLVETDH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
EQPFIEEVTEMLKDPSSRIAIMYSEQENWISDSNDENLQEFDVDWIEGQEEINTVIEDKQ
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHCCHHHCCHHHHHHHHHHHH
QISNQFHTANNTEVILVGAPIDDGGAVFVYKSLDMINQTKDQTTKLILLSAGIAILLTTF
HHHHHHCCCCCCEEEEEECCCCCCCEEEEEECHHHHHCCHHHHHEEHHHHCCHHHHHHHH
FAVFLSTRITSPLIKMKEAAHNLTRGEFNTKVPVLTRDEIGELAIEFNRMGRQLNYHINA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHH
LRQEKEQLSSIVSSMADGVFTLNREGEVLVINPPAKKYMDEWFYENPDESEGQNHLPTEV
HHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHH
KEALLEVITKEYAVLKESAVQGRSYVMLVTPLYDESHVRGCVAVIRDMTEERRLDKLRKD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FIANVSHELRTPISMLQGYSEAIVDDVASSKEEKNELAQIIYEESLRMGRLVNELLDLAR
HHHHHHHHHHCHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEAGQIQLRLDSVAIQPFIERIVHKFQGISREEMVELELTVDIEHQIGEMDPDRIEQVLT
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEHHHCCCCCHHHHHHHHH
NLIDNAIRHTSNNGFVKVLAVSNQDKLYVEVKDSGSGIPEEDLPFIFERFYKADKSRVKK
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
EKQGTGLGLAIAKNIIDAHHGSIYVKSKLDAGTTFSFEIPIKQN
HHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure
MFWKSVVGKLSLTILLLVSFVLCVLTFFLMQFFDNYHIQEAENEMEQMATKISSLVETDH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
EQPFIEEVTEMLKDPSSRIAIMYSEQENWISDSNDENLQEFDVDWIEGQEEINTVIEDKQ
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHCCHHHCCHHHHHHHHHHHH
QISNQFHTANNTEVILVGAPIDDGGAVFVYKSLDMINQTKDQTTKLILLSAGIAILLTTF
HHHHHHCCCCCCEEEEEECCCCCCCEEEEEECHHHHHCCHHHHHEEHHHHCCHHHHHHHH
FAVFLSTRITSPLIKMKEAAHNLTRGEFNTKVPVLTRDEIGELAIEFNRMGRQLNYHINA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHH
LRQEKEQLSSIVSSMADGVFTLNREGEVLVINPPAKKYMDEWFYENPDESEGQNHLPTEV
HHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHH
KEALLEVITKEYAVLKESAVQGRSYVMLVTPLYDESHVRGCVAVIRDMTEERRLDKLRKD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FIANVSHELRTPISMLQGYSEAIVDDVASSKEEKNELAQIIYEESLRMGRLVNELLDLAR
HHHHHHHHHHCHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEAGQIQLRLDSVAIQPFIERIVHKFQGISREEMVELELTVDIEHQIGEMDPDRIEQVLT
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEHHHCCCCCHHHHHHHHH
NLIDNAIRHTSNNGFVKVLAVSNQDKLYVEVKDSGSGIPEEDLPFIFERFYKADKSRVKK
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
EKQGTGLGLAIAKNIIDAHHGSIYVKSKLDAGTTFSFEIPIKQN
HHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]