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The map label for this gene is dapB

Identifier: 23099223

GI number: 23099223

Start: 1808308

End: 1809105

Strand: Reverse

Name: dapB

Synonym: OB1768

Alternate gene names: 23099223

Gene position: 1809105-1808308 (Counterclockwise)

Preceding gene: 23099224

Following gene: 23099222

Centisome position: 49.83

GC content: 36.97

Gene sequence:

>798_bases
ATGGCAATTAATATAATCGTAGCTGGACCTAGAGGTAGAATGGGATATGAAGCTGTACAAATGATTACAAAAGAAGATTC
TTTTCGTCTGGTTGCTTGCTTAGATCACAAACATGATGGATTAAATTTAGGTGAGCTGGAACAATTCTCAGATGATCTTC
AAGTACCTATTTACACGGATATTGATTCATGCTTAAAACAACATCAAGCAGATGTTTTTGTGGACTTAACAACGCCTGAA
GTGGGTTATAAACATACCAAAACAGCTTTAGAATATAAAGTGCGACCAGTAGTAGGGACAACAGGATTTACGGATGAACA
ACTATCTGAGCTTAAAGAACTTTCTAAGCAACAACAACGAGGATGTATCATTGCTCCGAATTTTGCAATAGGTGCTGTAT
TAATGATGAAATTCTCTAAAATGGCAGCAAAGTATTTCCCGAATGTAGAAATAATAGAAAAACATCATGATCAAAAATTA
GATGCGCCATCAGGTACTGCTAAAAAGACAGCTGAATTAATTCAAGATGTACGTGAAAGCCAAAAACAAGGACATCCAAA
AGAGGAAGAAACATTACCAGGTGCTAGAGGTGCAGATATGGATGGCATGCGCATTCATAGTATGCGTTTACCGGGATTAG
TAGCACATCAAGAGGTTATTTTCGGTGGTGCTGGTCAAACATTAACCATCAGTCATGACTCCATGAATCGTGCTTCTTTT
ATGGATGGTATAAGGGAATGTGTAAATCAAGTTATGGATTTAGAAGAACTTGTATATGGTTTGGAGAACCTATTGTAA

Upstream 100 bases:

>100_bases
ACTTGATTTTCAATTATCGGATGCATTTCAACAATCCATAGAAAAATTCGAAACAAGAGATAAAAATCGTTGGACAAGAA
AAGAAACAGGAGAATAATAC

Downstream 100 bases:

>100_bases
ATATAAGAATGATGGGAGTTTAGATATGAATATAGCATTAATCGCACATGACGAAAAGAAAGAAGACATGATTCAATTTA
CGACTGCATATACCCATGTG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAINIIVAGPRGRMGYEAVQMITKEDSFRLVACLDHKHDGLNLGELEQFSDDLQVPIYTDIDSCLKQHQADVFVDLTTPE
VGYKHTKTALEYKVRPVVGTTGFTDEQLSELKELSKQQQRGCIIAPNFAIGAVLMMKFSKMAAKYFPNVEIIEKHHDQKL
DAPSGTAKKTAELIQDVRESQKQGHPKEEETLPGARGADMDGMRIHSMRLPGLVAHQEVIFGGAGQTLTISHDSMNRASF
MDGIRECVNQVMDLEELVYGLENLL

Sequences:

>Translated_265_residues
MAINIIVAGPRGRMGYEAVQMITKEDSFRLVACLDHKHDGLNLGELEQFSDDLQVPIYTDIDSCLKQHQADVFVDLTTPE
VGYKHTKTALEYKVRPVVGTTGFTDEQLSELKELSKQQQRGCIIAPNFAIGAVLMMKFSKMAAKYFPNVEIIEKHHDQKL
DAPSGTAKKTAELIQDVRESQKQGHPKEEETLPGARGADMDGMRIHSMRLPGLVAHQEVIFGGAGQTLTISHDSMNRASF
MDGIRECVNQVMDLEELVYGLENLL
>Mature_264_residues
AINIIVAGPRGRMGYEAVQMITKEDSFRLVACLDHKHDGLNLGELEQFSDDLQVPIYTDIDSCLKQHQADVFVDLTTPEV
GYKHTKTALEYKVRPVVGTTGFTDEQLSELKELSKQQQRGCIIAPNFAIGAVLMMKFSKMAAKYFPNVEIIEKHHDQKLD
APSGTAKKTAELIQDVRESQKQGHPKEEETLPGARGADMDGMRIHSMRLPGLVAHQEVIFGGAGQTLTISHDSMNRASFM
DGIRECVNQVMDLEELVYGLENLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=277, Percent_Identity=27.0758122743682, Blast_Score=97, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_OCEIH (Q8EQD3)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692689.1
- ProteinModelPortal:   Q8EQD3
- SMR:   Q8EQD3
- GeneID:   1018262
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1768
- NMPDR:   fig|221109.1.peg.1769
- HOGENOM:   HBG594002
- OMA:   ARFYDHA
- ProtClustDB:   PRK00048
- BioCyc:   OIHE221109:OB1768-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29500; Mature: 29369

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINIIVAGPRGRMGYEAVQMITKEDSFRLVACLDHKHDGLNLGELEQFSDDLQVPIYTD
CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCEEEEC
IDSCLKQHQADVFVDLTTPEVGYKHTKTALEYKVRPVVGTTGFTDEQLSELKELSKQQQR
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHC
GCIIAPNFAIGAVLMMKFSKMAAKYFPNVEIIEKHHDQKLDAPSGTAKKTAELIQDVRES
CCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
QKQGHPKEEETLPGARGADMDGMRIHSMRLPGLVAHQEVIFGGAGQTLTISHDSMNRASF
HHCCCCCCHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHEECCCCCEEEEECCCCHHHHH
MDGIRECVNQVMDLEELVYGLENLL
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AINIIVAGPRGRMGYEAVQMITKEDSFRLVACLDHKHDGLNLGELEQFSDDLQVPIYTD
EEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCEEEEC
IDSCLKQHQADVFVDLTTPEVGYKHTKTALEYKVRPVVGTTGFTDEQLSELKELSKQQQR
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHC
GCIIAPNFAIGAVLMMKFSKMAAKYFPNVEIIEKHHDQKLDAPSGTAKKTAELIQDVRES
CCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
QKQGHPKEEETLPGARGADMDGMRIHSMRLPGLVAHQEVIFGGAGQTLTISHDSMNRASF
HHCCCCCCHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHEECCCCCEEEEECCCCHHHHH
MDGIRECVNQVMDLEELVYGLENLL
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376