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The map label for this gene is mgsA

Identifier: 23099222

GI number: 23099222

Start: 1807860

End: 1808282

Strand: Reverse

Name: mgsA

Synonym: OB1767

Alternate gene names: 23099222

Gene position: 1808282-1807860 (Counterclockwise)

Preceding gene: 23099223

Following gene: 23099221

Centisome position: 49.81

GC content: 39.48

Gene sequence:

>423_bases
ATGAATATAGCATTAATCGCACATGACGAAAAGAAAGAAGACATGATTCAATTTACGACTGCATATACCCATGTGTTGTC
AAAACATAGATTATTTGCTACCGGTACTACCGGCATGAAAATTTCGAATGCTACAGGCTTACAAATTCACCGTTTTCAAT
CCGGTCCACTTGGTGGAGATCAACAAATTGGAGCTATGATTGCGAACGGAGAGATGGATATGATTATCTTTTTCCGAGAT
CCACTAACTGCTCAACCTCATGAACCTGACGTAAGTGCATTAATGCGTTTATGTGATGTTCATCAGATACCATTAGTAAC
GAATATTGCAGGTGCAGAGATCTTTATTCATGGCCTTAGCAGAGGAGATTTGAAATGGAGAGAGATAATCAAAGAGAGAC
AAGAGAAAGAAGGGACACCGTGA

Upstream 100 bases:

>100_bases
GATGGTATAAGGGAATGTGTAAATCAAGTTATGGATTTAGAAGAACTTGTATATGGTTTGGAGAACCTATTGTAAATATA
AGAATGATGGGAGTTTAGAT

Downstream 100 bases:

>100_bases
AGAAGATAGGCATCACTTGTTATCCGACTGTCGGAGGGTCAGGTGTAATTGCTACAGAGCTAGGTAAACTATTAGCTGAA
AAGGGACATGAAATACATTT

Product: methylglyoxal synthase

Products: NA

Alternate protein names: MGS

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNIALIAHDEKKEDMIQFTTAYTHVLSKHRLFATGTTGMKISNATGLQIHRFQSGPLGGDQQIGAMIANGEMDMIIFFRD
PLTAQPHEPDVSALMRLCDVHQIPLVTNIAGAEIFIHGLSRGDLKWREIIKERQEKEGTP

Sequences:

>Translated_140_residues
MNIALIAHDEKKEDMIQFTTAYTHVLSKHRLFATGTTGMKISNATGLQIHRFQSGPLGGDQQIGAMIANGEMDMIIFFRD
PLTAQPHEPDVSALMRLCDVHQIPLVTNIAGAEIFIHGLSRGDLKWREIIKERQEKEGTP
>Mature_140_residues
MNIALIAHDEKKEDMIQFTTAYTHVLSKHRLFATGTTGMKISNATGLQIHRFQSGPLGGDQQIGAMIANGEMDMIIFFRD
PLTAQPHEPDVSALMRLCDVHQIPLVTNIAGAEIFIHGLSRGDLKWREIIKERQEKEGTP

Specific function: Unknown

COG id: COG1803

COG function: function code G; Methylglyoxal synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylglyoxal synthase family

Homologues:

Organism=Escherichia coli, GI87081809, Length=117, Percent_Identity=49.5726495726496, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGSA_OCEIH (Q8EQD4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692688.1
- ProteinModelPortal:   Q8EQD4
- SMR:   Q8EQD4
- GeneID:   1018261
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1767
- NMPDR:   fig|221109.1.peg.1768
- HOGENOM:   HBG298005
- OMA:   EPQPHDP
- ProtClustDB:   PRK05234
- BioCyc:   OIHE221109:OB1767-MONOMER
- BRENDA:   4.2.3.3
- HAMAP:   MF_00549
- InterPro:   IPR004363
- InterPro:   IPR018148
- InterPro:   IPR011607
- Gene3D:   G3DSA:3.40.50.1380
- PIRSF:   PIRSF006614
- SMART:   SM00851
- TIGRFAMs:   TIGR00160

Pfam domain/function: PF02142 MGS; SSF52335 MGS-like_dom

EC number: =4.2.3.3

Molecular weight: Translated: 15621; Mature: 15621

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01335 METHYLGLYOXAL_SYNTH

Important sites: ACT_SITE 60-60

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIALIAHDEKKEDMIQFTTAYTHVLSKHRLFATGTTGMKISNATGLQIHRFQSGPLGGD
CEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCEEEEEECCCCCCCC
QQIGAMIANGEMDMIIFFRDPLTAQPHEPDVSALMRLCDVHQIPLVTNIAGAEIFIHGLS
CCCCEEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCEEEEEECC
RGDLKWREIIKERQEKEGTP
CCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIALIAHDEKKEDMIQFTTAYTHVLSKHRLFATGTTGMKISNATGLQIHRFQSGPLGGD
CEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCEEEEEECCCCCCCC
QQIGAMIANGEMDMIIFFRDPLTAQPHEPDVSALMRLCDVHQIPLVTNIAGAEIFIHGLS
CCCCEEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCEEEEEECC
RGDLKWREIIKERQEKEGTP
CCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376