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The map label for this gene is aspB [H]

Identifier: 23099215

GI number: 23099215

Start: 1799114

End: 1800298

Strand: Reverse

Name: aspB [H]

Synonym: OB1760

Alternate gene names: 23099215

Gene position: 1800298-1799114 (Counterclockwise)

Preceding gene: 23099216

Following gene: 23099214

Centisome position: 49.59

GC content: 34.26

Gene sequence:

>1185_bases
ATGGAATTAGCACAAAGAGTTCAAACATTAACACCATCATCTACATTAGCGATAACTGCTAAGGCAAAAGATTTAAAAAA
ACAAGGGTTTGATGTCATTGGATTAGGAGCAGGTGAGCCAGACTTTAATACACCAGAATATATTATGGATGGCGCTAAGC
AAGCAATGAACAACGGCCTAACAAAGTATACTCCTGCAGGTGGAATTGCCGAGTTAAAACTAGCAATTATTGATAAATTT
AAACAAGACAACGGTCTTTCCTATAATGAAAAACAAATTATTGTGACAAACGGGGCAAAACATGCTTTATATACACTTTT
CCAAGTAATATTAAATAAGGAAGACGAAGTAATCATCCCATCACCATATTGGGTTAGTTATCCTGAACAAGTAAAACTTG
CTGAAGGAAACCCAATAATATTACCAGCTGCCGAGACTAATGATTTTAAAATAACTCCAACACAATTAGAAGAGGCTATT
ACTCCAAAAACAAAAGCAGTAATTATTAATTCACCTTCTAATCCAACTGGCTTAATGTATTCAAAAGAAGAATTAGCAGC
GCTCGGTGAAGTATGCCTTAAACATAATATCATCATTGTTTCTGACGAAATTTATGAAAAATTAATCTATACATCAAAAG
AACATGTATCTATAGCTTCCATATCTGATGAATTATATAACCAAACAATTATAATAAACGGTGTCTCTAAATCACATGCA
ATGACTGGTTGGAGAATTGGTTATGCTGCAGGTAATGAGACAATTATTAAAGCGATGACCAATCTTGCTTCTCATTCAAC
TTCAAACCCTACATCAATTGCACAATATGGAGCACTAGCAGCTTATACGAAAGATCCTGGTGATATATCATTAGAATATA
AGAAAATATTTGCTGAACGATTAGATGCCTTTTATAAATTGATACAAGATATCCCAGGAATGGAATGCATTAAACCAGAA
GGCGCATTTTATCTATTTCCTAATGCAAAAAAAGCAGCTGAAATGAATGGTTTTGCAACGGTTGATGAATGGGTAGCTGC
ACTTTTAGAAGAAGAAAAAGTTGCATTAGTACCAGGGTCTGGATTTGGGTCACCAGATAATGTACGTTTATCCTATGCAC
TGTCAATTGAGGAACTAACAGAAGCAGCTAATCGAATTCATCGATTTGTTCTAAATCATAAATAA

Upstream 100 bases:

>100_bases
ATAATAACTATGTGATGAATTATCATTCCATTACAGATGGATCTTTACAAGAACAATATAAATATTCGAAGATGTTTTAT
TAGTGAGAGGAGAAAAAAAC

Downstream 100 bases:

>100_bases
TGGAGGACTAAACCATGAAAATTACAATCGCACAGGCACCACAATATATAGAACAAGAAGTAACCATTGGTGCATGGTTA
TCTAACAAACGCTCTAGCGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MELAQRVQTLTPSSTLAITAKAKDLKKQGFDVIGLGAGEPDFNTPEYIMDGAKQAMNNGLTKYTPAGGIAELKLAIIDKF
KQDNGLSYNEKQIIVTNGAKHALYTLFQVILNKEDEVIIPSPYWVSYPEQVKLAEGNPIILPAAETNDFKITPTQLEEAI
TPKTKAVIINSPSNPTGLMYSKEELAALGEVCLKHNIIIVSDEIYEKLIYTSKEHVSIASISDELYNQTIIINGVSKSHA
MTGWRIGYAAGNETIIKAMTNLASHSTSNPTSIAQYGALAAYTKDPGDISLEYKKIFAERLDAFYKLIQDIPGMECIKPE
GAFYLFPNAKKAAEMNGFATVDEWVAALLEEEKVALVPGSGFGSPDNVRLSYALSIEELTEAANRIHRFVLNHK

Sequences:

>Translated_394_residues
MELAQRVQTLTPSSTLAITAKAKDLKKQGFDVIGLGAGEPDFNTPEYIMDGAKQAMNNGLTKYTPAGGIAELKLAIIDKF
KQDNGLSYNEKQIIVTNGAKHALYTLFQVILNKEDEVIIPSPYWVSYPEQVKLAEGNPIILPAAETNDFKITPTQLEEAI
TPKTKAVIINSPSNPTGLMYSKEELAALGEVCLKHNIIIVSDEIYEKLIYTSKEHVSIASISDELYNQTIIINGVSKSHA
MTGWRIGYAAGNETIIKAMTNLASHSTSNPTSIAQYGALAAYTKDPGDISLEYKKIFAERLDAFYKLIQDIPGMECIKPE
GAFYLFPNAKKAAEMNGFATVDEWVAALLEEEKVALVPGSGFGSPDNVRLSYALSIEELTEAANRIHRFVLNHK
>Mature_394_residues
MELAQRVQTLTPSSTLAITAKAKDLKKQGFDVIGLGAGEPDFNTPEYIMDGAKQAMNNGLTKYTPAGGIAELKLAIIDKF
KQDNGLSYNEKQIIVTNGAKHALYTLFQVILNKEDEVIIPSPYWVSYPEQVKLAEGNPIILPAAETNDFKITPTQLEEAI
TPKTKAVIINSPSNPTGLMYSKEELAALGEVCLKHNIIIVSDEIYEKLIYTSKEHVSIASISDELYNQTIIINGVSKSHA
MTGWRIGYAAGNETIIKAMTNLASHSTSNPTSIAQYGALAAYTKDPGDISLEYKKIFAERLDAFYKLIQDIPGMECIKPE
GAFYLFPNAKKAAEMNGFATVDEWVAALLEEEKVALVPGSGFGSPDNVRLSYALSIEELTEAANRIHRFVLNHK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=362, Percent_Identity=25.1381215469613, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI169881279, Length=362, Percent_Identity=25.1381215469613, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI56713256, Length=383, Percent_Identity=26.8929503916449, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI56713254, Length=383, Percent_Identity=26.8929503916449, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI169881281, Length=361, Percent_Identity=21.3296398891967, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=25.2604166666667, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1788627, Length=391, Percent_Identity=29.4117647058824, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=25.5376344086022, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1788722, Length=381, Percent_Identity=28.3464566929134, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=26.2032085561497, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=29.8469387755102, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=420, Percent_Identity=29.5238095238095, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17567369, Length=376, Percent_Identity=27.9255319148936, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71981209, Length=322, Percent_Identity=24.223602484472, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=323, Percent_Identity=30.3405572755418, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=26.1971830985915, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=342, Percent_Identity=28.3625730994152, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573069, Length=345, Percent_Identity=28.695652173913, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24646114, Length=345, Percent_Identity=28.695652173913, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28573067, Length=345, Percent_Identity=28.695652173913, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28573065, Length=345, Percent_Identity=28.695652173913, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI18859735, Length=326, Percent_Identity=25.1533742331288, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45551451, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641770, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641760, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641768, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641766, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641764, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43168; Mature: 43168

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELAQRVQTLTPSSTLAITAKAKDLKKQGFDVIGLGAGEPDFNTPEYIMDGAKQAMNNGL
CCHHHHHHHCCCCCEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPAGGIAELKLAIIDKFKQDNGLSYNEKQIIVTNGAKHALYTLFQVILNKEDEVIIP
CEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEC
SPYWVSYPEQVKLAEGNPIILPAAETNDFKITPTQLEEAITPKTKAVIINSPSNPTGLMY
CCCEECCCCEEEEECCCEEEEECCCCCCEEECHHHHHHHCCCCCEEEEEECCCCCCCEEE
SKEELAALGEVCLKHNIIIVSDEIYEKLIYTSKEHVSIASISDELYNQTIIINGVSKSHA
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCEEEEEHHHHHCCCEEEEECCCCCCC
MTGWRIGYAAGNETIIKAMTNLASHSTSNPTSIAQYGALAAYTKDPGDISLEYKKIFAER
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEECCCCCCEEHHHHHHHHHH
LDAFYKLIQDIPGMECIKPEGAFYLFPNAKKAAEMNGFATVDEWVAALLEEEKVALVPGS
HHHHHHHHHHCCCCEEECCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEECCC
GFGSPDNVRLSYALSIEELTEAANRIHRFVLNHK
CCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELAQRVQTLTPSSTLAITAKAKDLKKQGFDVIGLGAGEPDFNTPEYIMDGAKQAMNNGL
CCHHHHHHHCCCCCEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPAGGIAELKLAIIDKFKQDNGLSYNEKQIIVTNGAKHALYTLFQVILNKEDEVIIP
CEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEC
SPYWVSYPEQVKLAEGNPIILPAAETNDFKITPTQLEEAITPKTKAVIINSPSNPTGLMY
CCCEECCCCEEEEECCCEEEEECCCCCCEEECHHHHHHHCCCCCEEEEEECCCCCCCEEE
SKEELAALGEVCLKHNIIIVSDEIYEKLIYTSKEHVSIASISDELYNQTIIINGVSKSHA
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCEEEEEHHHHHCCCEEEEECCCCCCC
MTGWRIGYAAGNETIIKAMTNLASHSTSNPTSIAQYGALAAYTKDPGDISLEYKKIFAER
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEECCCCCCEEHHHHHHHHHH
LDAFYKLIQDIPGMECIKPEGAFYLFPNAKKAAEMNGFATVDEWVAALLEEEKVALVPGS
HHHHHHHHHHCCCCEEECCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEECCC
GFGSPDNVRLSYALSIEELTEAANRIHRFVLNHK
CCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]