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The map label for this gene is cdd [H]

Identifier: 23099206

GI number: 23099206

Start: 1790233

End: 1790634

Strand: Reverse

Name: cdd [H]

Synonym: OB1751

Alternate gene names: 23099206

Gene position: 1790634-1790233 (Counterclockwise)

Preceding gene: 23099207

Following gene: 23099205

Centisome position: 49.32

GC content: 35.57

Gene sequence:

>402_bases
ATGAACAAGAATCAATTATTAGATGCTTCTCTAAAGGCGATGGATAGTGCGTATGTACCGTATTCGACTTTTCCGGTAGG
AGCAGCATTGTTAACTAAATCAGGCAAGCTTTATACAGGTTGTAATATAGAAAACGCAGCATATCCTGTTACATGTTGTG
CAGAAAGAGTAGCTATATTTAAAGCAATTTCTGAAGGAGAGACGCAATTTGCAGAAATGGCAGTAGCAGCCAATACGAAA
AGACCTGTTCCTCCTTGTGGTTCTTGTCGACAAGTTATGAGTGAATTCTTTACTTCGTCAATGAAGATTCATTTAACGAA
TTTAAATAAAGAAGTAAAGACGTTGACAATAGAAGAATTATTACCTTTTTCTTTCCAACCAGATGATTTGGAGAATAATT
AA

Upstream 100 bases:

>100_bases
CGTGTTTGACCTATTATTAGAAGATATAGAACAGTAAGACCTTTACAGTTTTCTAAAAATAAACTATAATAACGAACACT
ACTAATAAAGGATGAAATGG

Downstream 100 bases:

>100_bases
TGGGAACTCCTCTATTTATCCTATTATGAATTTTTAATTTTAAGAAGGAGACTGGCAATCAGTTTCTTTTTTTGTGTTAT
AATAATAAGTAAATGTTCTA

Product: cytidine:deoxycytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MNKNQLLDASLKAMDSAYVPYSTFPVGAALLTKSGKLYTGCNIENAAYPVTCCAERVAIFKAISEGETQFAEMAVAANTK
RPVPPCGSCRQVMSEFFTSSMKIHLTNLNKEVKTLTIEELLPFSFQPDDLENN

Sequences:

>Translated_133_residues
MNKNQLLDASLKAMDSAYVPYSTFPVGAALLTKSGKLYTGCNIENAAYPVTCCAERVAIFKAISEGETQFAEMAVAANTK
RPVPPCGSCRQVMSEFFTSSMKIHLTNLNKEVKTLTIEELLPFSFQPDDLENN
>Mature_133_residues
MNKNQLLDASLKAMDSAYVPYSTFPVGAALLTKSGKLYTGCNIENAAYPVTCCAERVAIFKAISEGETQFAEMAVAANTK
RPVPPCGSCRQVMSEFFTSSMKIHLTNLNKEVKTLTIEELLPFSFQPDDLENN

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=131, Percent_Identity=50.381679389313, Blast_Score=133, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=46.4566929133858, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17551074, Length=131, Percent_Identity=40.4580152671756, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=128, Percent_Identity=37.5, Blast_Score=88, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24582741, Length=129, Percent_Identity=46.5116279069767, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24582744, Length=139, Percent_Identity=39.568345323741, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920920, Length=128, Percent_Identity=43.75, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14579; Mature: 14579

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNQLLDASLKAMDSAYVPYSTFPVGAALLTKSGKLYTGCNIENAAYPVTCCAERVAIF
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHH
KAISEGETQFAEMAVAANTKRPVPPCGSCRQVMSEFFTSSMKIHLTNLNKEVKTLTIEEL
HHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHEEEHHHH
LPFSFQPDDLENN
CCCCCCCCCCCCC
>Mature Secondary Structure
MNKNQLLDASLKAMDSAYVPYSTFPVGAALLTKSGKLYTGCNIENAAYPVTCCAERVAIF
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHH
KAISEGETQFAEMAVAANTKRPVPPCGSCRQVMSEFFTSSMKIHLTNLNKEVKTLTIEEL
HHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHEEEHHHH
LPFSFQPDDLENN
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]