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The map label for this gene is uvrX [H]

Identifier: 23098816

GI number: 23098816

Start: 1408824

End: 1410074

Strand: Reverse

Name: uvrX [H]

Synonym: OB1361

Alternate gene names: 23098816

Gene position: 1410074-1408824 (Counterclockwise)

Preceding gene: 23098822

Following gene: 23098815

Centisome position: 38.84

GC content: 38.21

Gene sequence:

>1251_bases
ATGGATTATTCCAGTTATCCACGTAATGATGTTCTATGTATTGACATGCGTTCATTCTATGCGAGTGTAGAAGCAGTCAA
ACTCGGATTAGATCCGATGAAAGTAATGCTTGCTGTTGTTGGCGACCCCAACCGATCGGGAAGCATTGTGCTCGCCGCTT
CTCCTGAGTTAAAGCGACGTTATGGAATAAGTAATGTCAGTCGTTATTTTGAATTGCCAGATGACCCGGAAATTCATATT
GTCCCTGCCCATATGGCAGACTATATACACATGTCTTTGCAAATTACTGATTTACTACAGCAATATGCACCTATAGAGGC
AATTCATCCTTATTCGGTCGATGAAGTATGGATTACAGTTAATGGTTTACAACACTTATTTGGAACCCGAGAAGAAATTG
CTGAAAAAATTAAAGCTGATATTTTAGATTCCTTTGGTATTACTTGTTCCGTTGGAATTGGTGATAATAAATTTTTAGCA
AAAGTTGTCATGGATCTTCATGCAAAAAAACAAGGAATTGCGGAATGTACGTATGAAGATGTGAAAGAAAAGCTTTGGCC
ACACCCGATTGAATCTATCTGGGGAATCGGCAGAAGAATGAAGCGAAATTTGAACCGAATGGGCATTATTACGTTAGGCC
AGCTTGCGAATTATAATCTTGACCATTTAAAAAAACGATTCGGAGTAATGGGAGAGCAACTTTATTGGCACGCATGGGGA
ATCGATTTAAGCCCTGTGTTCGGTGATTTTTCAAAACAAGAACAAAAAGGCTTTGGGCATGGTATATCTTTGCTACGTGA
TTATACAAAAGAAGATATTCCTTATTGTATTCTCGACCTCTGTGAAGAAGTATGTCGAAGAGCTCGTACAGCAAATAAAT
CAGGTAGAACCATTCATTTAGGGATTTCTTATTCAAAAGAAACTGGCGGAGGATTTTCTCGATCACAATCCATTGATCTT
CCAACAAATATTACCTTAGATGTTTACGATATTTGCATGCAATTATTTAATAAATTTTACGATGGTAAAAGTATGGTTCG
TCATGTATATGTCACACTAACCAACCTTAAAGATAAGCAGGAAACACAGTTGGACTTATTTGAAGATCGTACGAAAAAAA
ATGATATTGGATATGTCATGGATGCAATCCGCGATAAATATGGATCCACCGCCATTCTGCGTGCATCCAGTTATACCCAA
GCTGGGATCACTATAGAACGAAGCAAAAAAATTGGCGGGCACTACGCTTAA

Upstream 100 bases:

>100_bases
CTATGTTCTTGCTTGCAGTTATCCTGTAACAAATTTCCATTGTTATTTTTTACTGTTCTACATATAATAGAACATACGTT
CTTATGAAAGGGTGATAAAT

Downstream 100 bases:

>100_bases
TATAAAGGGAACCTTCATTTTGTCATGTAATACTGTCCGATACATGCGGGATAAACTAATGCACATTCTGAATTCCAATC
ATGTAAATTCATGCTATAAT

Product: DNA-damage repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDYSSYPRNDVLCIDMRSFYASVEAVKLGLDPMKVMLAVVGDPNRSGSIVLAASPELKRRYGISNVSRYFELPDDPEIHI
VPAHMADYIHMSLQITDLLQQYAPIEAIHPYSVDEVWITVNGLQHLFGTREEIAEKIKADILDSFGITCSVGIGDNKFLA
KVVMDLHAKKQGIAECTYEDVKEKLWPHPIESIWGIGRRMKRNLNRMGIITLGQLANYNLDHLKKRFGVMGEQLYWHAWG
IDLSPVFGDFSKQEQKGFGHGISLLRDYTKEDIPYCILDLCEEVCRRARTANKSGRTIHLGISYSKETGGGFSRSQSIDL
PTNITLDVYDICMQLFNKFYDGKSMVRHVYVTLTNLKDKQETQLDLFEDRTKKNDIGYVMDAIRDKYGSTAILRASSYTQ
AGITIERSKKIGGHYA

Sequences:

>Translated_416_residues
MDYSSYPRNDVLCIDMRSFYASVEAVKLGLDPMKVMLAVVGDPNRSGSIVLAASPELKRRYGISNVSRYFELPDDPEIHI
VPAHMADYIHMSLQITDLLQQYAPIEAIHPYSVDEVWITVNGLQHLFGTREEIAEKIKADILDSFGITCSVGIGDNKFLA
KVVMDLHAKKQGIAECTYEDVKEKLWPHPIESIWGIGRRMKRNLNRMGIITLGQLANYNLDHLKKRFGVMGEQLYWHAWG
IDLSPVFGDFSKQEQKGFGHGISLLRDYTKEDIPYCILDLCEEVCRRARTANKSGRTIHLGISYSKETGGGFSRSQSIDL
PTNITLDVYDICMQLFNKFYDGKSMVRHVYVTLTNLKDKQETQLDLFEDRTKKNDIGYVMDAIRDKYGSTAILRASSYTQ
AGITIERSKKIGGHYA
>Mature_416_residues
MDYSSYPRNDVLCIDMRSFYASVEAVKLGLDPMKVMLAVVGDPNRSGSIVLAASPELKRRYGISNVSRYFELPDDPEIHI
VPAHMADYIHMSLQITDLLQQYAPIEAIHPYSVDEVWITVNGLQHLFGTREEIAEKIKADILDSFGITCSVGIGDNKFLA
KVVMDLHAKKQGIAECTYEDVKEKLWPHPIESIWGIGRRMKRNLNRMGIITLGQLANYNLDHLKKRFGVMGEQLYWHAWG
IDLSPVFGDFSKQEQKGFGHGISLLRDYTKEDIPYCILDLCEEVCRRARTANKSGRTIHLGISYSKETGGGFSRSQSIDL
PTNITLDVYDICMQLFNKFYDGKSMVRHVYVTLTNLKDKQETQLDLFEDRTKKNDIGYVMDAIRDKYGSTAILRASSYTQ
AGITIERSKKIGGHYA

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI7706681, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1786425, Length=233, Percent_Identity=29.6137339055794, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787432, Length=441, Percent_Identity=24.9433106575964, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19923006, Length=232, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 47187; Mature: 47187

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50173 UMUC ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYSSYPRNDVLCIDMRSFYASVEAVKLGLDPMKVMLAVVGDPNRSGSIVLAASPELKRR
CCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHH
YGISNVSRYFELPDDPEIHIVPAHMADYIHMSLQITDLLQQYAPIEAIHPYSVDEVWITV
HCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
NGLQHLFGTREEIAEKIKADILDSFGITCSVGIGDNKFLAKVVMDLHAKKQGIAECTYED
CHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHCCHHH
VKEKLWPHPIESIWGIGRRMKRNLNRMGIITLGQLANYNLDHLKKRFGVMGEQLYWHAWG
HHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCHHHHHHHHCCCCCCEEEEEEC
IDLSPVFGDFSKQEQKGFGHGISLLRDYTKEDIPYCILDLCEEVCRRARTANKSGRTIHL
CCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
GISYSKETGGGFSRSQSIDLPTNITLDVYDICMQLFNKFYDGKSMVRHVYVTLTNLKDKQ
EEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHEEEEECCCCCH
ETQLDLFEDRTKKNDIGYVMDAIRDKYGSTAILRASSYTQAGITIERSKKIGGHYA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MDYSSYPRNDVLCIDMRSFYASVEAVKLGLDPMKVMLAVVGDPNRSGSIVLAASPELKRR
CCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHH
YGISNVSRYFELPDDPEIHIVPAHMADYIHMSLQITDLLQQYAPIEAIHPYSVDEVWITV
HCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
NGLQHLFGTREEIAEKIKADILDSFGITCSVGIGDNKFLAKVVMDLHAKKQGIAECTYED
CHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHCCHHH
VKEKLWPHPIESIWGIGRRMKRNLNRMGIITLGQLANYNLDHLKKRFGVMGEQLYWHAWG
HHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCHHHHHHHHCCCCCCEEEEEEC
IDLSPVFGDFSKQEQKGFGHGISLLRDYTKEDIPYCILDLCEEVCRRARTANKSGRTIHL
CCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
GISYSKETGGGFSRSQSIDLPTNITLDVYDICMQLFNKFYDGKSMVRHVYVTLTNLKDKQ
EEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHEEEEECCCCCH
ETQLDLFEDRTKKNDIGYVMDAIRDKYGSTAILRASSYTQAGITIERSKKIGGHYA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]