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The map label for this gene is mqo

Identifier: 23098401

GI number: 23098401

Start: 992340

End: 993848

Strand: Direct

Name: mqo

Synonym: OB0946

Alternate gene names: 23098401

Gene position: 992340-993848 (Clockwise)

Preceding gene: 23098400

Following gene: 23098402

Centisome position: 27.33

GC content: 37.64

Gene sequence:

>1509_bases
ATGAGTAACAAACACACGCAAGCAGACGTTATCTTAATTGGTGCTGGCATAATGAGTGCTACATTAGGATCACTTCTGAA
AGAACTATCACCAAACTTAGAAATTAGAGTATTTGAGAAGCTCGAAAATCCTGGAGAAGAAAGCTCCAATGAATGGAATA
ATGCTGGTACAGGGCATTCAGCATTATGTGAGCTTAATTATACTTCCGAAAGAACAGATGGATCTATTGATATCAATAAA
GCGGTTAAGGTCAATGAACAATTTCAACTATCAAGACAGTTTTGGTCTTACCTTGTAAATCGTAACTTGATTCGTAATCC
CGAAGACTTTATCAGAGCGTTACCACATATAAGCTTAGTACAAGGTGAGGATAATGTTACATTCCTTAGAAAGCGCTTTA
AGGCATTAGTGAATCATCCATTATTTAATGGTATGGAGTTCTCCGATGATAACGAAAAGTTAAAAGAGTGGATGCCGCTT
ATTATGGATAAACGAGATACAAATGAACCTATTGCAGCGACAAAGATTGATTCTGGTACAGATGTTAATTTCGGTGCTTT
AACGCGTCTTTTGTTTCAAGAGTTTGATCATAAAGGCATTGATGTGAATTACAATCATAGTGTAGAAGATATTAAACGAA
ATAGTGAAGGATTATGGGAAGTAAAAGTTCATGATATGAACGATGAAAAGATTGAATACCATACTGCTAAATTCGTCTTC
ATCGGTGCTGGTGGTGGAAGTTTGCCATTACTTCAAAAAACAGGTATCAAGGAATCGAAACATATTGGTGGCTTCCCTGT
TAGTGGTTTATTTATGGTATGTAATAATCCGGAAGTAATCGAGCAGCACCATGCGAAGGTCTATGGGAAAGCTAAAGTTG
GTGCACCACCGATGTCTGTTCCGCATCTCGATACGAGGTTTATTGACGGGAAAAAATCGTTACTATTTGGACCTTTTGCC
GGTTTTTCACCAAAATTTTTAAAAACAGGTTCATTATTTGATTTAATGCATTCTGTGAAATCGGATAATCTTTTTACCAT
GCTTTCTGCTGGTATGAAGGAATTACCGTTAACAAAATATCTCATTCAACAGGTTGTCCTATCGAATGAAAAACGTATGG
AAGAATTACGTGAATTCATTCCTAATGCACAAAGTAAAGATTGGGATATTGTTATAGCAGGACAGCGTGTCCAAGTAATC
AAGGATACGGAAGATGGAGGAAAAGGTACACTACAATTTGGTACGGAAGTTGTTTGTGGTGAGGATGGAACCATGGCAGC
ACTATTAGGCGCTTCCCCAGGGGCATCTACCGCAGTACATGTGATGCTAGAAGTGATACAAAAATGTTTCCCTGAGCATT
TGCAAGAGTGGGAACCAAAAATTAAAGAAATGATACCTTCTTATGGCATAGCACTTTCTGAAAATCCAGAGTTATATAAA
GAGATTGAGGTATCTATCGAAAAGGCACTTGGTTTAAAGAACGAAGAGCCCATGGTAATACCTTCTTGA

Upstream 100 bases:

>100_bases
TCATATATATTAAAAAATTTTCACAATAGGTTTATAATGGAGAATAAGGGGTTAATGTTTTATTTATGTTTTAAAATTTT
GGGGGATAAGGAAGGATAAA

Downstream 100 bases:

>100_bases
TAAGCAAAAGAAAGATCTGTGATATCCTATCACAGATCTTTTTCTATGCCGTCAAAGTAGGTTGATAGTCTTACCTACTT
TTACATCTTTATTTCAGTTC

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSNKHTQADVILIGAGIMSATLGSLLKELSPNLEIRVFEKLENPGEESSNEWNNAGTGHSALCELNYTSERTDGSIDINK
AVKVNEQFQLSRQFWSYLVNRNLIRNPEDFIRALPHISLVQGEDNVTFLRKRFKALVNHPLFNGMEFSDDNEKLKEWMPL
IMDKRDTNEPIAATKIDSGTDVNFGALTRLLFQEFDHKGIDVNYNHSVEDIKRNSEGLWEVKVHDMNDEKIEYHTAKFVF
IGAGGGSLPLLQKTGIKESKHIGGFPVSGLFMVCNNPEVIEQHHAKVYGKAKVGAPPMSVPHLDTRFIDGKKSLLFGPFA
GFSPKFLKTGSLFDLMHSVKSDNLFTMLSAGMKELPLTKYLIQQVVLSNEKRMEELREFIPNAQSKDWDIVIAGQRVQVI
KDTEDGGKGTLQFGTEVVCGEDGTMAALLGASPGASTAVHVMLEVIQKCFPEHLQEWEPKIKEMIPSYGIALSENPELYK
EIEVSIEKALGLKNEEPMVIPS

Sequences:

>Translated_502_residues
MSNKHTQADVILIGAGIMSATLGSLLKELSPNLEIRVFEKLENPGEESSNEWNNAGTGHSALCELNYTSERTDGSIDINK
AVKVNEQFQLSRQFWSYLVNRNLIRNPEDFIRALPHISLVQGEDNVTFLRKRFKALVNHPLFNGMEFSDDNEKLKEWMPL
IMDKRDTNEPIAATKIDSGTDVNFGALTRLLFQEFDHKGIDVNYNHSVEDIKRNSEGLWEVKVHDMNDEKIEYHTAKFVF
IGAGGGSLPLLQKTGIKESKHIGGFPVSGLFMVCNNPEVIEQHHAKVYGKAKVGAPPMSVPHLDTRFIDGKKSLLFGPFA
GFSPKFLKTGSLFDLMHSVKSDNLFTMLSAGMKELPLTKYLIQQVVLSNEKRMEELREFIPNAQSKDWDIVIAGQRVQVI
KDTEDGGKGTLQFGTEVVCGEDGTMAALLGASPGASTAVHVMLEVIQKCFPEHLQEWEPKIKEMIPSYGIALSENPELYK
EIEVSIEKALGLKNEEPMVIPS
>Mature_501_residues
SNKHTQADVILIGAGIMSATLGSLLKELSPNLEIRVFEKLENPGEESSNEWNNAGTGHSALCELNYTSERTDGSIDINKA
VKVNEQFQLSRQFWSYLVNRNLIRNPEDFIRALPHISLVQGEDNVTFLRKRFKALVNHPLFNGMEFSDDNEKLKEWMPLI
MDKRDTNEPIAATKIDSGTDVNFGALTRLLFQEFDHKGIDVNYNHSVEDIKRNSEGLWEVKVHDMNDEKIEYHTAKFVFI
GAGGGSLPLLQKTGIKESKHIGGFPVSGLFMVCNNPEVIEQHHAKVYGKAKVGAPPMSVPHLDTRFIDGKKSLLFGPFAG
FSPKFLKTGSLFDLMHSVKSDNLFTMLSAGMKELPLTKYLIQQVVLSNEKRMEELREFIPNAQSKDWDIVIAGQRVQVIK
DTEDGGKGTLQFGTEVVCGEDGTMAALLGASPGASTAVHVMLEVIQKCFPEHLQEWEPKIKEMIPSYGIALSENPELYKE
IEVSIEKALGLKNEEPMVIPS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=506, Percent_Identity=50.395256916996, Blast_Score=520, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_OCEIH (Q8CV11)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691867.1
- ProteinModelPortal:   Q8CV11
- GeneID:   1016695
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0946
- NMPDR:   fig|221109.1.peg.948
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BioCyc:   OIHE221109:OB0946-MONOMER
- BRENDA:   1.1.99.16
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 56074; Mature: 55943

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKHTQADVILIGAGIMSATLGSLLKELSPNLEIRVFEKLENPGEESSNEWNNAGTGHS
CCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCC
ALCELNYTSERTDGSIDINKAVKVNEQFQLSRQFWSYLVNRNLIRNPEDFIRALPHISLV
EEEEECCCCCCCCCCEEECCEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEE
QGEDNVTFLRKRFKALVNHPLFNGMEFSDDNEKLKEWMPLIMDKRDTNEPIAATKIDSGT
ECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
DVNFGALTRLLFQEFDHKGIDVNYNHSVEDIKRNSEGLWEVKVHDMNDEKIEYHTAKFVF
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEE
IGAGGGSLPLLQKTGIKESKHIGGFPVSGLFMVCNNPEVIEQHHAKVYGKAKVGAPPMSV
EECCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHEEECEECCCCCCCC
PHLDTRFIDGKKSLLFGPFAGFSPKFLKTGSLFDLMHSVKSDNLFTMLSAGMKELPLTKY
CCCCCEEECCCCCEEEECCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHCCHHHCCHHHH
LIQQVVLSNEKRMEELREFIPNAQSKDWDIVIAGQRVQVIKDTEDGGKGTLQFGTEVVCG
HHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCCEEEEECCEEEEC
EDGTMAALLGASPGASTAVHVMLEVIQKCFPEHLQEWEPKIKEMIPSYGIALSENPELYK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHCCEEECCCCHHHH
EIEVSIEKALGLKNEEPMVIPS
HHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SNKHTQADVILIGAGIMSATLGSLLKELSPNLEIRVFEKLENPGEESSNEWNNAGTGHS
CCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCC
ALCELNYTSERTDGSIDINKAVKVNEQFQLSRQFWSYLVNRNLIRNPEDFIRALPHISLV
EEEEECCCCCCCCCCEEECCEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEE
QGEDNVTFLRKRFKALVNHPLFNGMEFSDDNEKLKEWMPLIMDKRDTNEPIAATKIDSGT
ECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
DVNFGALTRLLFQEFDHKGIDVNYNHSVEDIKRNSEGLWEVKVHDMNDEKIEYHTAKFVF
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEE
IGAGGGSLPLLQKTGIKESKHIGGFPVSGLFMVCNNPEVIEQHHAKVYGKAKVGAPPMSV
EECCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHEEECEECCCCCCCC
PHLDTRFIDGKKSLLFGPFAGFSPKFLKTGSLFDLMHSVKSDNLFTMLSAGMKELPLTKY
CCCCCEEECCCCCEEEECCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHCCHHHCCHHHH
LIQQVVLSNEKRMEELREFIPNAQSKDWDIVIAGQRVQVIKDTEDGGKGTLQFGTEVVCG
HHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCCEEEEECCEEEEC
EDGTMAALLGASPGASTAVHVMLEVIQKCFPEHLQEWEPKIKEMIPSYGIALSENPELYK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHCCEEECCCCHHHH
EIEVSIEKALGLKNEEPMVIPS
HHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376