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The map label for this gene is perR [H]

Identifier: 23098360

GI number: 23098360

Start: 955474

End: 955917

Strand: Direct

Name: perR [H]

Synonym: OB0905

Alternate gene names: 23098360

Gene position: 955474-955917 (Clockwise)

Preceding gene: 23098359

Following gene: 23098362

Centisome position: 26.32

GC content: 37.84

Gene sequence:

>444_bases
GTGTCTGAACAACGTCTGCGTCAAGCAATCGATACATTGAAGGAATCAGGCGTCCGTATTACACCACAGAGACACGCAGT
ACTGGAATTTCTTTTAAATGCTATGGTTCATCCAACTGCGGATGAAATCTATAAAGCTTTAGAAGGTAAGTTTCCAAATA
TGAGTGTTGCAACCGTGTATAATAACTTACGTGTATTGAAAGATATCGGACTTGTCCGTGAGTTGACCTATGGTGATTCC
TCTAGTCGATTTGACTGTAACACGTCAGATCATTACCATATTATTTGTAATGAATGTGGGAAGATAGTTGATTTTCATTA
TCCTTCATTAAATGAGGTTGAATCTCTAGCGGAACAAGTAACTGGATTTGATGTAAGTCATCATCGCTTAGAGGTCTATG
GTAAATGCGATGATTGTCAAGCAGTAAATACGAAAAAGCATTAA

Upstream 100 bases:

>100_bases
TGTTGACAGAAAACAGCCTATGAAGGTAAACTATTTATAAGGATTATAATATAATAATTTTATTAACTAAAATATATTAC
TGAAAGAGAGGTGTTTAACG

Downstream 100 bases:

>100_bases
TGGCATTAAAATACCCCGTCAGGCGACGGGGTTTATTTTTATGCTTAAATTAATTTGATTATTTCTTTTTATATTTACGT
GAATTATACTTCTCGTCAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSEQRLRQAIDTLKESGVRITPQRHAVLEFLLNAMVHPTADEIYKALEGKFPNMSVATVYNNLRVLKDIGLVRELTYGDS
SSRFDCNTSDHYHIICNECGKIVDFHYPSLNEVESLAEQVTGFDVSHHRLEVYGKCDDCQAVNTKKH

Sequences:

>Translated_147_residues
MSEQRLRQAIDTLKESGVRITPQRHAVLEFLLNAMVHPTADEIYKALEGKFPNMSVATVYNNLRVLKDIGLVRELTYGDS
SSRFDCNTSDHYHIICNECGKIVDFHYPSLNEVESLAEQVTGFDVSHHRLEVYGKCDDCQAVNTKKH
>Mature_146_residues
SEQRLRQAIDTLKESGVRITPQRHAVLEFLLNAMVHPTADEIYKALEGKFPNMSVATVYNNLRVLKDIGLVRELTYGDSS
SRFDCNTSDHYHIICNECGKIVDFHYPSLNEVESLAEQVTGFDVSHHRLEVYGKCDDCQAVNTKKH

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=30.0751879699248, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16727; Mature: 16596

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQRLRQAIDTLKESGVRITPQRHAVLEFLLNAMVHPTADEIYKALEGKFPNMSVATVY
CCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVLKDIGLVRELTYGDSSSRFDCNTSDHYHIICNECGKIVDFHYPSLNEVESLAEQV
HHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHH
TGFDVSHHRLEVYGKCDDCQAVNTKKH
HCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SEQRLRQAIDTLKESGVRITPQRHAVLEFLLNAMVHPTADEIYKALEGKFPNMSVATVY
CHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVLKDIGLVRELTYGDSSSRFDCNTSDHYHIICNECGKIVDFHYPSLNEVESLAEQV
HHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHH
TGFDVSHHRLEVYGKCDDCQAVNTKKH
HCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]