Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 23098099

GI number: 23098099

Start: 679855

End: 680823

Strand: Direct

Name: thiL [H]

Synonym: OB0644

Alternate gene names: 23098099

Gene position: 679855-680823 (Clockwise)

Preceding gene: 23098095

Following gene: 23098100

Centisome position: 18.73

GC content: 38.8

Gene sequence:

>969_bases
ATGGATGAGTTTTCTTTTATAGATTCGATTAAGCCGACATATTATCGACAGCCTTCTCTGTTAAAAGGAATTGGAGATGA
TGCTGCTGTTTTTCGTAGTTCAAAGGATATTGTTACGGCAGTAGATACTTTTGTAGAGGATGTACATTTTTCCCGTTCTA
CAATGGAACCGTATCATATCGGCTATCGAGCATTAGGGGCCAATATAAGTGATTTAGCAGCAATGGGAGCTTCACCTAGT
TTCTATTTAGTATCTATTGTAATACCAAAGAATTGGACTCAAGCGGAGCTATCTCAGATATATTCAGGTATGGATGATTT
AGCATCAAAGTATCATATGGATATTATTGGTGGAGATACTGTTTCCGGTAAGCAATTAACCATCTCTATTACAGTAATTG
GATATACGATCACAAATAAAGCGCGATATCGTCAGCATGCAAAAGAAGGAGACATTGTCTTTGTTACGGGGACATTAGGA
GACTCTCTAGCAGGGTTTCATATTCTGACCAGCGACAATGAAAACAACCGATATGTTGATCAAGATTTTTATATTCATCG
GCATCGAAAACCGGAACCGAGAGTGGCTTTTGCGCAAGCTCTAGAAAGTCTGGACAGAGTATCTTTAAATGATGTAAGTG
ATGGGATTGCCAATGAGGCAAGTGAGATCGCAGAAGCTTCTAATGTGTCCATTGTATTACGTGAAAATGATATACCAGTT
GCACCTTCCTTTTATCAATTTACGTATGAGCAACAATATCAGTGGAAATTGTCTGGTGGAGAGGATTTTGAACTCCTAGG
GACAGTGGCTAAAGGTGACTGGGCTGTTGTAAATGAAGCTGCTGAGAAGACAAATACCCAATTGACGGTAATTGGAAGTG
TTGTAGAAGAAGAAAAGCATCCTGTTTATATAGAAGATAATGCTATGCGTAAAGTGCTTAAGAAAAGCGGATATACGCAT
TTGAAGTAG

Upstream 100 bases:

>100_bases
TTTTTAGTTTGTAGACATTATTTAGTCGTCCAATTTTTTTCTTTTTTCTTTTGTTTTTGCTATGATAGTTGGTAGTGAAG
ATAAAGAATGGTGATGTGAA

Downstream 100 bases:

>100_bases
GTGAATTAAATGAAAATACAGCTTGGTTCTCCGGAAGAAACAAAATCATTCGGCGAAAGACTAGCTAAGTCGTTGCGTCC
GGGTGATGTTATTACGTTAG

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDEFSFIDSIKPTYYRQPSLLKGIGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHIGYRALGANISDLAAMGASPS
FYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDTVSGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLG
DSLAGFHILTSDNENNRYVDQDFYIHRHRKPEPRVAFAQALESLDRVSLNDVSDGIANEASEIAEASNVSIVLRENDIPV
APSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEAAEKTNTQLTVIGSVVEEEKHPVYIEDNAMRKVLKKSGYTH
LK

Sequences:

>Translated_322_residues
MDEFSFIDSIKPTYYRQPSLLKGIGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHIGYRALGANISDLAAMGASPS
FYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDTVSGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLG
DSLAGFHILTSDNENNRYVDQDFYIHRHRKPEPRVAFAQALESLDRVSLNDVSDGIANEASEIAEASNVSIVLRENDIPV
APSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEAAEKTNTQLTVIGSVVEEEKHPVYIEDNAMRKVLKKSGYTH
LK
>Mature_322_residues
MDEFSFIDSIKPTYYRQPSLLKGIGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHIGYRALGANISDLAAMGASPS
FYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDTVSGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLG
DSLAGFHILTSDNENNRYVDQDFYIHRHRKPEPRVAFAQALESLDRVSLNDVSDGIANEASEIAEASNVSIVLRENDIPV
APSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEAAEKTNTQLTVIGSVVEEEKHPVYIEDNAMRKVLKKSGYTH
LK

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=301, Percent_Identity=33.2225913621262, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35872; Mature: 35872

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFSFIDSIKPTYYRQPSLLKGIGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHI
CCCCCHHHCCCCCCCCCCHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHC
GYRALGANISDLAAMGASPSFYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDT
CHHHHCCCHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHEEEEECCCC
VSGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLGDSLAGFHILTSDNENNRYVD
CCCCEEEEEEEEEEEEECCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEC
QDFYIHRHRKPEPRVAFAQALESLDRVSLNDVSDGIANEASEIAEASNVSIVLRENDIPV
CCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
APSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEAAEKTNTQLTVIGSVVEEEKH
CCCHHEEEECCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEHHHHCCCC
PVYIEDNAMRKVLKKSGYTHLK
CEEEECHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDEFSFIDSIKPTYYRQPSLLKGIGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHI
CCCCCHHHCCCCCCCCCCHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHC
GYRALGANISDLAAMGASPSFYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDT
CHHHHCCCHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHEEEEECCCC
VSGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLGDSLAGFHILTSDNENNRYVD
CCCCEEEEEEEEEEEEECCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEC
QDFYIHRHRKPEPRVAFAQALESLDRVSLNDVSDGIANEASEIAEASNVSIVLRENDIPV
CCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
APSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEAAEKTNTQLTVIGSVVEEEKH
CCCHHEEEECCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEHHHHCCCC
PVYIEDNAMRKVLKKSGYTHLK
CEEEECHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]