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The map label for this gene is katX [H]

Identifier: 23097890

GI number: 23097890

Start: 461503

End: 463101

Strand: Reverse

Name: katX [H]

Synonym: OB0435

Alternate gene names: 23097890

Gene position: 463101-461503 (Counterclockwise)

Preceding gene: 23097894

Following gene: 23097884

Centisome position: 12.76

GC content: 38.84

Gene sequence:

>1599_bases
ATGGCAAAAAAAGATGAATCCATGAATAAAAGTAATCTAGAAAATGATATGTCACTTACAAACCGTCAAGGTCACCCTGT
AACAAACAATCAAAACATACGTACAGTAAGTAACCGTGGTCCCGCTACATTAGAAAACTATGACTTCATTGAGAAAATCA
GTCATTTTGACCGTGAGAAAGTGCCAGAAAGAATCGTACATGCACGCGGAGCTGGAGCCCATGGATATTTTGAAACATAC
GGCACTGTCGGAAATGATCCAGTATCCAAATATACTAGAGCAAAAGTATTTCAAGATAAAGGTAAACAAACTCCTGTATT
TGTACGTTTTTCAACAGTAGTACATGGCAATCACTCTCCAGAAACAGTTCGTGACCCACGTGGGTTTGCGGTGAAATTTT
ATACTGAGGATGGAAACTGGGATTTAGTAGGAAATAACCTCAAAATATTTTTTATTCGTGATGCAATGAAATTCCCAGAT
ATGATTCACGCCTTCCGTCCTGATCCAGTAACTAACATCCAAGATTCTGAAAGATTCTTTGATTTTTGTGCAAACTCTCC
TGAATCCTTTCATATGGTGACCTTTGTATATTCACCTTGGGGAATCCCAGCAAATTACCGGATGATGCAAGGTTCTGGAG
TGAATACGTATAAGTGGGTTAATAAAGATGGTGAAGCTGTTCTTGTAAAGTATCACTGGGAACCCAAGCAAGGGATTAAA
AATTTAACTACCAAAGAAGCTGAAGAAATTCAAGCTACCAACTTCAACCATGCAACACAAGATTTATATGATGCAATTGA
AAACGGAGACTATCCAGAATGGGAATTATTTGTTCAAATTATGAGTGATGATGAACATCCAGAACTAGACTTTGATCCAT
TAGACGATACAAAATTATGGCCAGAGGATCAGTTCCCATGGCATCCAGTCGGTAAAATGGTATTAAATAAGAACCCTGAA
AATTACTTTACAGAAGTAGAACAAGCCGCATTTGGTACTGGTGTTTTAGTGGATGGATTAGATTTCTCTGACGATAAAAT
GCTTCAAGGAAGAACGTTCTCTTATTCTGATACTCAACGCTATCGTGTAGGAGCAAACTACCTGCAAGTTCCTGTTAATG
AATCCAAAAAACGTGTCGCAACGAATCATGAAGGTGGTCAGATGCGTCAGAAAAATGATAAAGCACCTAGTCAAAACCCA
CATATTAACTACGAGCCATCTGTACTTGGCGGCTTAGAAGAAAATGAACAGACCGGTAAAGAATACACACCTCATATCGA
GGGTAATCTTGTACGTGAATCCATTGATCGGAATGATAACACGAAGCAAGCTGGACATACTTTCCGTGAATTTGAAGAAT
GGGAAAAAGCAGAATTAATTTCCAATCTTGTCGGCGACCTTTCTGTAAGTGATCAGCGAATCCAAGATAAGATGATTGCT
TTAGCAGAAGAAGCTGATGATGAATATGGTAGACGTTTACGAGAAGGATTAGAACAGGCGAAGAAGATGGGAACACCACA
TAATCCTTTAGGTGCAAAAGATGCTGAACAAGCACCGAAAAAAGCAATAGATAAAGGACATGACGCAGACCCGTATTAA

Upstream 100 bases:

>100_bases
ATGTTGAAACTGCGATTATATTTAATTCCATTGGCAAAGATAAAAAAGAATATATCTGTTGGTACTTACCAAATAACAAA
TGGAATGAGGGATAATACAC

Downstream 100 bases:

>100_bases
GTTAAAATATAAAATAAAAACCCGAGCCACATAACTGATCTCCAATCTGTGGCTAGGGTTTTTTATATGACCATGTTAAT
GAGTTACTTTTCTTCGGCGC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MAKKDESMNKSNLENDMSLTNRQGHPVTNNQNIRTVSNRGPATLENYDFIEKISHFDREKVPERIVHARGAGAHGYFETY
GTVGNDPVSKYTRAKVFQDKGKQTPVFVRFSTVVHGNHSPETVRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAMKFPD
MIHAFRPDPVTNIQDSERFFDFCANSPESFHMVTFVYSPWGIPANYRMMQGSGVNTYKWVNKDGEAVLVKYHWEPKQGIK
NLTTKEAEEIQATNFNHATQDLYDAIENGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWPEDQFPWHPVGKMVLNKNPE
NYFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGANYLQVPVNESKKRVATNHEGGQMRQKNDKAPSQNP
HINYEPSVLGGLEENEQTGKEYTPHIEGNLVRESIDRNDNTKQAGHTFREFEEWEKAELISNLVGDLSVSDQRIQDKMIA
LAEEADDEYGRRLREGLEQAKKMGTPHNPLGAKDAEQAPKKAIDKGHDADPY

Sequences:

>Translated_532_residues
MAKKDESMNKSNLENDMSLTNRQGHPVTNNQNIRTVSNRGPATLENYDFIEKISHFDREKVPERIVHARGAGAHGYFETY
GTVGNDPVSKYTRAKVFQDKGKQTPVFVRFSTVVHGNHSPETVRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAMKFPD
MIHAFRPDPVTNIQDSERFFDFCANSPESFHMVTFVYSPWGIPANYRMMQGSGVNTYKWVNKDGEAVLVKYHWEPKQGIK
NLTTKEAEEIQATNFNHATQDLYDAIENGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWPEDQFPWHPVGKMVLNKNPE
NYFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGANYLQVPVNESKKRVATNHEGGQMRQKNDKAPSQNP
HINYEPSVLGGLEENEQTGKEYTPHIEGNLVRESIDRNDNTKQAGHTFREFEEWEKAELISNLVGDLSVSDQRIQDKMIA
LAEEADDEYGRRLREGLEQAKKMGTPHNPLGAKDAEQAPKKAIDKGHDADPY
>Mature_531_residues
AKKDESMNKSNLENDMSLTNRQGHPVTNNQNIRTVSNRGPATLENYDFIEKISHFDREKVPERIVHARGAGAHGYFETYG
TVGNDPVSKYTRAKVFQDKGKQTPVFVRFSTVVHGNHSPETVRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAMKFPDM
IHAFRPDPVTNIQDSERFFDFCANSPESFHMVTFVYSPWGIPANYRMMQGSGVNTYKWVNKDGEAVLVKYHWEPKQGIKN
LTTKEAEEIQATNFNHATQDLYDAIENGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWPEDQFPWHPVGKMVLNKNPEN
YFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGANYLQVPVNESKKRVATNHEGGQMRQKNDKAPSQNPH
INYEPSVLGGLEENEQTGKEYTPHIEGNLVRESIDRNDNTKQAGHTFREFEEWEKAELISNLVGDLSVSDQRIQDKMIAL
AEEADDEYGRRLREGLEQAKKMGTPHNPLGAKDAEQAPKKAIDKGHDADPY

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=483, Percent_Identity=42.8571428571429, Blast_Score=400, Evalue=1e-111,
Organism=Escherichia coli, GI48994891, Length=435, Percent_Identity=43.9080459770115, Blast_Score=355, Evalue=5e-99,
Organism=Caenorhabditis elegans, GI25147792, Length=485, Percent_Identity=43.5051546391753, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI25151141, Length=485, Percent_Identity=43.5051546391753, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI71998444, Length=497, Percent_Identity=41.4486921529175, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6320462, Length=376, Percent_Identity=43.8829787234042, Blast_Score=331, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321525, Length=341, Percent_Identity=39.2961876832845, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI17981717, Length=513, Percent_Identity=40.5458089668616, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI19920968, Length=510, Percent_Identity=38.0392156862745, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 60830; Mature: 60699

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKDESMNKSNLENDMSLTNRQGHPVTNNQNIRTVSNRGPATLENYDFIEKISHFDREK
CCCCCCCCCHHCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
VPERIVHARGAGAHGYFETYGTVGNDPVSKYTRAKVFQDKGKQTPVFVRFSTVVHGNHSP
HHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCC
ETVRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAMKFPDMIHAFRPDPVTNIQDSERFF
CCCCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHCHHHHHHCCCCCCCCCCHHHHHH
DFCANSPESFHMVTFVYSPWGIPANYRMMQGSGVNTYKWVNKDGEAVLVKYHWEPKQGIK
HHHCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCEEEEEEECCHHHHHH
NLTTKEAEEIQATNFNHATQDLYDAIENGDYPEWELFVQIMSDDEHPELDFDPLDDTKLW
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHEEEECCCCCCCCCCCCCCCCCCCC
PEDQFPWHPVGKMVLNKNPENYFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQR
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEECCCCCCCCCCCC
YRVGANYLQVPVNESKKRVATNHEGGQMRQKNDKAPSQNPHINYEPSVLGGLEENEQTGK
EEECCCEEEECCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCHHHCCCCCCHHCCC
EYTPHIEGNLVRESIDRNDNTKQAGHTFREFEEWEKAELISNLVGDLSVSDQRIQDKMIA
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LAEEADDEYGRRLREGLEQAKKMGTPHNPLGAKDAEQAPKKAIDKGHDADPY
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKKDESMNKSNLENDMSLTNRQGHPVTNNQNIRTVSNRGPATLENYDFIEKISHFDREK
CCCCCCCCHHCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
VPERIVHARGAGAHGYFETYGTVGNDPVSKYTRAKVFQDKGKQTPVFVRFSTVVHGNHSP
HHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCC
ETVRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAMKFPDMIHAFRPDPVTNIQDSERFF
CCCCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHCHHHHHHCCCCCCCCCCHHHHHH
DFCANSPESFHMVTFVYSPWGIPANYRMMQGSGVNTYKWVNKDGEAVLVKYHWEPKQGIK
HHHCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCEEEEEEECCHHHHHH
NLTTKEAEEIQATNFNHATQDLYDAIENGDYPEWELFVQIMSDDEHPELDFDPLDDTKLW
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHEEEECCCCCCCCCCCCCCCCCCCC
PEDQFPWHPVGKMVLNKNPENYFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQR
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEECCCCCCCCCCCC
YRVGANYLQVPVNESKKRVATNHEGGQMRQKNDKAPSQNPHINYEPSVLGGLEENEQTGK
EEECCCEEEECCCCCCHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCHHHCCCCCCHHCCC
EYTPHIEGNLVRESIDRNDNTKQAGHTFREFEEWEKAELISNLVGDLSVSDQRIQDKMIA
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LAEEADDEYGRRLREGLEQAKKMGTPHNPLGAKDAEQAPKKAIDKGHDADPY
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]