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The map label for this gene is queC

Identifier: 23097767

GI number: 23097767

Start: 342975

End: 343640

Strand: Direct

Name: queC

Synonym: OB0312

Alternate gene names: 23097767

Gene position: 342975-343640 (Clockwise)

Preceding gene: 23097766

Following gene: 23097768

Centisome position: 9.45

GC content: 37.99

Gene sequence:

>666_bases
ATGACTGGTAAAAAGGCAGTAGTTATATTAAGTGGCGGATTAGATAGTACGACGTGTATGGGAGTTGGCAAGGAAGCAGG
GTATGAATTGTATCCAATTTCTTTCCACTATGGTCAGCGCCATGATCGTGAGATTGAAAATGCTAAAAAGGTAGCTTCCT
ATTTTAATGTAACGGAACACAAAGTATTTTCACTAGAATTTTTAAAAGAGATTGGTGGCAGTTCTTTGACCGATCAATCA
ATGGAAGTAAGTCAAGAAGGTGTCGGTGAAGATGTACCAAATACATATGTTCCGGGAAGAAATACAATTTTCCTATCAAT
TGCTGCTTCTTATGCAGAAGCCATAGGTGCAGAAAAAATATATGTAGGTGTATCGGCGGTTGATTATAGTGGATATCCAG
ATTGTCGTCCTGAGTTTATAGAAGCAATGCAACAAACTATATATCAAGGGACCAACGCAAATCCTGCAATGACGATTGAG
GCTCCACTGATTGATTTATCAAAAGGAGATACCGTCAAATTAGGAATGAAATTAAACGTACCGTATCACTTAACTACTTC
TTGTTACTTAGGTGGAGAAGAAGCATGTGGTGAATGTGATAGTTGTAGATTGAGATTACAAGGATTTGAAGAAGCTGGTG
CCACAGATCCTATCAAGTATATGTAA

Upstream 100 bases:

>100_bases
TATTACCTAGTAAAGGATAAAACCAATCCTTCACGTCTAGATACTAATATGCTAGTTTAGAAGAAAGAACTTGGAATATA
TTACATAGGAGTGTTAAATA

Downstream 100 bases:

>100_bases
TAGTTTATTTTATATGAAGCCTATTAGTACTAGGAGGTTAGTTTATGAACACATTTGATGAATTTCTACAGACAATGGAA
AATCCTAATCATCGTTCAAG

Product: transcriptional regulator

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTGKKAVVILSGGLDSTTCMGVGKEAGYELYPISFHYGQRHDREIENAKKVASYFNVTEHKVFSLEFLKEIGGSSLTDQS
MEVSQEGVGEDVPNTYVPGRNTIFLSIAASYAEAIGAEKIYVGVSAVDYSGYPDCRPEFIEAMQQTIYQGTNANPAMTIE
APLIDLSKGDTVKLGMKLNVPYHLTTSCYLGGEEACGECDSCRLRLQGFEEAGATDPIKYM

Sequences:

>Translated_221_residues
MTGKKAVVILSGGLDSTTCMGVGKEAGYELYPISFHYGQRHDREIENAKKVASYFNVTEHKVFSLEFLKEIGGSSLTDQS
MEVSQEGVGEDVPNTYVPGRNTIFLSIAASYAEAIGAEKIYVGVSAVDYSGYPDCRPEFIEAMQQTIYQGTNANPAMTIE
APLIDLSKGDTVKLGMKLNVPYHLTTSCYLGGEEACGECDSCRLRLQGFEEAGATDPIKYM
>Mature_220_residues
TGKKAVVILSGGLDSTTCMGVGKEAGYELYPISFHYGQRHDREIENAKKVASYFNVTEHKVFSLEFLKEIGGSSLTDQSM
EVSQEGVGEDVPNTYVPGRNTIFLSIAASYAEAIGAEKIYVGVSAVDYSGYPDCRPEFIEAMQQTIYQGTNANPAMTIEA
PLIDLSKGDTVKLGMKLNVPYHLTTSCYLGGEEACGECDSCRLRLQGFEEAGATDPIKYM

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=219, Percent_Identity=39.2694063926941, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_OCEIH (Q8ETE9)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691233.1
- ProteinModelPortal:   Q8ETE9
- SMR:   Q8ETE9
- GeneID:   1015538
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0312
- NMPDR:   fig|221109.1.peg.315
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK2519602
- BioCyc:   OIHE221109:OB0312-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24018; Mature: 23887

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKKAVVILSGGLDSTTCMGVGKEAGYELYPISFHYGQRHDREIENAKKVASYFNVTEH
CCCCEEEEEEECCCCCCEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCHHH
KVFSLEFLKEIGGSSLTDQSMEVSQEGVGEDVPNTYVPGRNTIFLSIAASYAEAIGAEKI
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCEE
YVGVSAVDYSGYPDCRPEFIEAMQQTIYQGTNANPAMTIEAPLIDLSKGDTVKLGMKLNV
EEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCCEEEEEEEECC
PYHLTTSCYLGGEEACGECDSCRLRLQGFEEAGATDPIKYM
CEEEEEEEEECCHHHCCCCCHHEEEEECCHHCCCCCCCCCC
>Mature Secondary Structure 
TGKKAVVILSGGLDSTTCMGVGKEAGYELYPISFHYGQRHDREIENAKKVASYFNVTEH
CCCEEEEEEECCCCCCEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCHHH
KVFSLEFLKEIGGSSLTDQSMEVSQEGVGEDVPNTYVPGRNTIFLSIAASYAEAIGAEKI
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCEE
YVGVSAVDYSGYPDCRPEFIEAMQQTIYQGTNANPAMTIEAPLIDLSKGDTVKLGMKLNV
EEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCCEEEEEEEECC
PYHLTTSCYLGGEEACGECDSCRLRLQGFEEAGATDPIKYM
CEEEEEEEEECCHHHCCCCCHHEEEEECCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376