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The map label for this gene is nusG [H]

Identifier: 23097561

GI number: 23097561

Start: 124553

End: 125089

Strand: Direct

Name: nusG [H]

Synonym: OB0106

Alternate gene names: 23097561

Gene position: 124553-125089 (Clockwise)

Preceding gene: 23097560

Following gene: 23097562

Centisome position: 3.43

GC content: 37.62

Gene sequence:

>537_bases
ATGGAGAAAAACTGGTACGTCGTTCATACTTACTCAGGGTATGAAAATAAAGTGAAAATGAATCTAGAAAAACGTGTTGA
ATCAATGGGGATGGAAGATAAAATATTTCGAGTGATAGTCCCAGAAGATGAAGAAGCGGAGATCAAAAACGGCAAGAAAA
AAATGGTCAAGAAAAAATCATTCCCAGGCTATGTTTTAACAGAAATGGTAATGACGGATGACTCTTGGTATGTCGTGCGT
AATACACCAGGTGTAACTGGATTCGTAGGTTCTAGCGGACATGGCGCAAAACCAACTCCGTTAATGCCTGGCGAAATTGA
TGTAGTATTAAAACGTATGGGTGTATCTGAACCAACTGTACAAGTAGATTTCGAGATAAAAGAAAACGTTCGTGTTACCG
ATGGACCGTTTACCGACTTTACAGGTTCAATCGAACATATAGATACGGACAAGCAGAAAATTAAAGTACATGTAAATATG
TTTGGTAGAGAAACTCCGGTAGAACTAGATTTTTCACAAGTAGAAAAACTATCATAA

Upstream 100 bases:

>100_bases
AAAGATGAATGATAGCTAGAATAAGCGGAGTATATTACTACAGCGGGTTTTTAAAACCTATTCATTCTGTTTCTAGCTTT
GTCTCAACCTCTAAATGAAG

Downstream 100 bases:

>100_bases
ACTCCCATCACTCAAAGCTTGCATTTTTTCAAAATACATGCTAAAATTCTTATGTTATTCATGTGCCGCCAAGTTGGTGC
ACATGGTAAATTTGAGTGGG

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MEKNWYVVHTYSGYENKVKMNLEKRVESMGMEDKIFRVIVPEDEEAEIKNGKKKMVKKKSFPGYVLTEMVMTDDSWYVVR
NTPGVTGFVGSSGHGAKPTPLMPGEIDVVLKRMGVSEPTVQVDFEIKENVRVTDGPFTDFTGSIEHIDTDKQKIKVHVNM
FGRETPVELDFSQVEKLS

Sequences:

>Translated_178_residues
MEKNWYVVHTYSGYENKVKMNLEKRVESMGMEDKIFRVIVPEDEEAEIKNGKKKMVKKKSFPGYVLTEMVMTDDSWYVVR
NTPGVTGFVGSSGHGAKPTPLMPGEIDVVLKRMGVSEPTVQVDFEIKENVRVTDGPFTDFTGSIEHIDTDKQKIKVHVNM
FGRETPVELDFSQVEKLS
>Mature_178_residues
MEKNWYVVHTYSGYENKVKMNLEKRVESMGMEDKIFRVIVPEDEEAEIKNGKKKMVKKKSFPGYVLTEMVMTDDSWYVVR
NTPGVTGFVGSSGHGAKPTPLMPGEIDVVLKRMGVSEPTVQVDFEIKENVRVTDGPFTDFTGSIEHIDTDKQKIKVHVNM
FGRETPVELDFSQVEKLS

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=177, Percent_Identity=45.7627118644068, Blast_Score=166, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 20252; Mature: 20252

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNWYVVHTYSGYENKVKMNLEKRVESMGMEDKIFRVIVPEDEEAEIKNGKKKMVKKKS
CCCCEEEEEEECCCCCEEEECHHHHHHHCCCCCCEEEEEECCCCCCHHHCCHHHHHHHCC
FPGYVLTEMVMTDDSWYVVRNTPGVTGFVGSSGHGAKPTPLMPGEIDVVLKRMGVSEPTV
CCCEEEEEEEEECCCEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEE
QVDFEIKENVRVTDGPFTDFTGSIEHIDTDKQKIKVHVNMFGRETPVELDFSQVEKLS
EEEEEECCCEEECCCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCEECHHHHHCCC
>Mature Secondary Structure
MEKNWYVVHTYSGYENKVKMNLEKRVESMGMEDKIFRVIVPEDEEAEIKNGKKKMVKKKS
CCCCEEEEEEECCCCCEEEECHHHHHHHCCCCCCEEEEEECCCCCCHHHCCHHHHHHHCC
FPGYVLTEMVMTDDSWYVVRNTPGVTGFVGSSGHGAKPTPLMPGEIDVVLKRMGVSEPTV
CCCEEEEEEEEECCCEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEE
QVDFEIKENVRVTDGPFTDFTGSIEHIDTDKQKIKVHVNMFGRETPVELDFSQVEKLS
EEEEEECCCEEECCCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968510; 9384377 [H]