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The map label for this gene is sigH [H]

Identifier: 23097558

GI number: 23097558

Start: 122942

End: 123595

Strand: Direct

Name: sigH [H]

Synonym: OB0103

Alternate gene names: 23097558

Gene position: 122942-123595 (Clockwise)

Preceding gene: 23097557

Following gene: 23097559

Centisome position: 3.39

GC content: 36.24

Gene sequence:

>654_bases
TTGGTGAATATCGGGCAAATAGACACGACCAACAAGGGATTAGAGCAGCTTGATGATACTGATTTGCTACAATTCATTCG
TCAAGGGAATAGTCACGCGCTAGACCTCCTTATACAACGGTACATTAGTTTTGTACGAGCAAAAGCACGAACGTATTTTC
TTGTAGGTGCGGATAAAGAGGATATTATCCAAGAAGGGATGATTGGTCTATATAAAGCTATACGTGATTATGATGTGGAC
AAGCTATCCTCTTTTAAAGCATTTGCTGAATTATGTGTCACAAGACAAATTATCACGGCGATCAAAACAGCCACACGTCA
AAAACATATTCCATTAAATTCATATGTATCTTTGGACAAGCCGATTTATGATGAAGAATCAGATAGAACTTTGTTAGATA
TAATAGGTGGATCCATTGATGTAGATCCACAAGAATTATTGATCAGTCAAGAAGATTATGGGACGCTAGAACATAAATTA
TCGAAATTATTAAGCGACTTAGAAAAGAAAGTATTGCAATTATATTTAGACGGACGCACCTATCAAGAGATTTCAGAGCA
TTTAAATCGTCATGTAAAGTCGATTGATAATGCCCTGCAGCGAGTGAAACGAAAATTAGAGCAACTAATGGAATCAAATG
GAGTTTCTTTGTAA

Upstream 100 bases:

>100_bases
ATTATGACTATTTCCTGGTTTAGGTCAAGTTGACGGTTTTAAAACGCTTCCTGTATAATATTTCCTATACTATAGAAGCG
GAATTTGCAGGAGGCGATCT

Downstream 100 bases:

>100_bases
ATATAAAAAAACTTTACGACAGAAATCGACAACAAGAATCTGAAAATTACGGGAAGATTTTACTGTTTCTTGTAACAGAA
GCGATAGATTGTTGTGATGC

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MVNIGQIDTTNKGLEQLDDTDLLQFIRQGNSHALDLLIQRYISFVRAKARTYFLVGADKEDIIQEGMIGLYKAIRDYDVD
KLSSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLLDIIGGSIDVDPQELLISQEDYGTLEHKL
SKLLSDLEKKVLQLYLDGRTYQEISEHLNRHVKSIDNALQRVKRKLEQLMESNGVSL

Sequences:

>Translated_217_residues
MVNIGQIDTTNKGLEQLDDTDLLQFIRQGNSHALDLLIQRYISFVRAKARTYFLVGADKEDIIQEGMIGLYKAIRDYDVD
KLSSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLLDIIGGSIDVDPQELLISQEDYGTLEHKL
SKLLSDLEKKVLQLYLDGRTYQEISEHLNRHVKSIDNALQRVKRKLEQLMESNGVSL
>Mature_217_residues
MVNIGQIDTTNKGLEQLDDTDLLQFIRQGNSHALDLLIQRYISFVRAKARTYFLVGADKEDIIQEGMIGLYKAIRDYDVD
KLSSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLLDIIGGSIDVDPQELLISQEDYGTLEHKL
SKLLSDLEKKVLQLYLDGRTYQEISEHLNRHVKSIDNALQRVKRKLEQLMESNGVSL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 24829; Mature: 24829

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00622 HTH_LUXR_1 ; PS00715 SIGMA70_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNIGQIDTTNKGLEQLDDTDLLQFIRQGNSHALDLLIQRYISFVRAKARTYFLVGADKE
CCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCHH
DIIQEGMIGLYKAIRDYDVDKLSSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLDK
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
PIYDEESDRTLLDIIGGSIDVDPQELLISQEDYGTLEHKLSKLLSDLEKKVLQLYLDGRT
CCCCCCCCCHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
YQEISEHLNRHVKSIDNALQRVKRKLEQLMESNGVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVNIGQIDTTNKGLEQLDDTDLLQFIRQGNSHALDLLIQRYISFVRAKARTYFLVGADKE
CCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCHH
DIIQEGMIGLYKAIRDYDVDKLSSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLDK
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
PIYDEESDRTLLDIIGGSIDVDPQELLISQEDYGTLEHKLSKLLSDLEKKVLQLYLDGRT
CCCCCCCCCHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
YQEISEHLNRHVKSIDNALQRVKRKLEQLMESNGVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]