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The map label for this gene is infC [H]

Identifier: 257168076

GI number: 257168076

Start: 2101059

End: 2101610

Strand: Direct

Name: infC [H]

Synonym: y1904

Alternate gene names: 257168076

Gene position: 2101059-2101610 (Clockwise)

Preceding gene: 22125796

Following gene: 22125798

Centisome position: 45.67

GC content: 47.46

Gene sequence:

>552_bases
ATTAAAGGCGGAAAACGAGTTCAACCGGCGCGTCCTAATCGCATCAACAAAGAGATTCGCGCCACAGAAGTTCGCTTAAC
AGGCGTCGATGGTGAACAGATTGGTATTGTCAGTCTGAATGAAGCTCTTGAAAAAGCCGAGGAAGCTGGTGTTGATTTAG
TAGAAATCAGTCCGAATGCCGAGCCGCCAGTTTGTCGTATAATGGATTACGGCAAATTCCTCTACGAGAAGAGCAAGTCG
ACAAAAGAACAGAAGAAGAAGCAAAAAGTCATTCAGGTTAAGGAAATTAAATTCCGTCCTGGTACCGATGATGGCGACTA
TCAGGTCAAACTACGCAACCTGATTCGCTTTCTGGAAGATGGCGATAAAGCCAAAATCACCCTGCGGTTCCGTGGGCGTG
AAATGGCGCACCAACAGATCGGTATGGAAGTGCTTAACCGCGTCCGTAAAGATCTGTGTGAAGATTCTGATTTGGCCGTT
GTCGAGTCCTTCCCGACTCGTATCGAAGGCCGTCAGATGATCATGGTGCTCGCACCTAAGAAGAGACAGTAA

Upstream 100 bases:

>100_bases
CCGCGGTAAAGACTTAGGAAGTTTAGACGTCAACGTGGTCGTAGACCAGCTGCTAGCAGAAATTCGCAGCCGTAGTCTTC
ATCAACTGGAGGAATAAAGT

Downstream 100 bases:

>100_bases
GGCATTCAAGTAGCAGGTTTCTCTACGCTTGCGTAGTAAGAAACCTGTTCGCCTAGCTAGCTCGTTGTAATTAACAATGC
GAAGTGGATATATTCAATGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKGGKRVQPARPNRINKEIRATEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKS
TKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAV
VESFPTRIEGRQMIMVLAPKKRQ

Sequences:

>Translated_183_residues
MKGGKRVQPARPNRINKEIRATEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKS
TKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAV
VESFPTRIEGRQMIMVLAPKKRQ
>Mature_183_residues
MKGGKRVQPARPNRINKEIRATEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKS
TKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAV
VESFPTRIEGRQMIMVLAPKKRQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=183, Percent_Identity=89.6174863387978, Blast_Score=299, Evalue=8e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20937; Mature: 20937

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGGKRVQPARPNRINKEIRATEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCC
EPPVCRIMDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLED
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEHEEEEECCCCCCCCCEEHHHHHHHHHHC
GDKAKITLRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPK
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCEEEEEECCC
KRQ
CCC
>Mature Secondary Structure
MKGGKRVQPARPNRINKEIRATEVRLTGVDGEQIGIVSLNEALEKAEEAGVDLVEISPNA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCC
EPPVCRIMDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLED
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEHEEEEECCCCCCCCCEEHHHHHHHHHHC
GDKAKITLRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAVVESFPTRIEGRQMIMVLAPK
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCEEEEEECCC
KRQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405963 [H]