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The map label for this gene is hofQ [H]

Identifier: 22127802

GI number: 22127802

Start: 4387085

End: 4388209

Strand: Direct

Name: hofQ [H]

Synonym: y3932

Alternate gene names: 22127802

Gene position: 4387085-4388209 (Clockwise)

Preceding gene: 22127800

Following gene: 22127803

Centisome position: 95.36

GC content: 48.18

Gene sequence:

>1125_bases
TTGCAGGCTCTGGCTGACTATCGGCAACTTAATCTGATCACGACTACCGGTGTGGGCGGCAATCTCAGTTTGCGGTTGAT
TGAAGTGCCTTGGGAGCAGGCATTGGCGATCATTCTGCGGATGGGGCGTTTGAAAGCTGAGCGCGAGGGGACCGTGATGA
TGGTCTTTACCGAACAGGAAATTCAAGAAAGGCAGCAGCGGACGAAACAGCAAGCTGCGCCAGAAGCACTGGCTAACCTG
ACATTGGCATTGCAATACGCGAATGCTGAACAGGTGGCTGACAGTTTGGATCCGCTGCAAGGTGGGCTGCTTTCTCCATT
GGGCAGTGTGGTGGCCGATAAGCGGACGAACACATTATTGATTCGCGATACGCCCGCTTCACTGGCATTGTTAAAAAACT
GGCTGATTGAGATGGATTTACCGTTACAACAAGTACAGTTATCCGCGCATATTGTGACCATCAGCAGTGAAGATTTACAA
GAGCTGGGTGTGCGCTGGGGGATGGGGGAGGGCAAGGGAAACACCGCGCTCAGAATCAATGATTTTAATGTCAATTTGCC
GTTGCCAAATAGCGCCGCGAGCGTGGGGTTTCATGTGGCCCGTATTGGTGGCCGCCTGCTGGAGCTTGAGTTGAGTGCGT
TGGAGCAAGAGAATCAGGTCGATATTATTGCCAGCCCACGCTTAATTACTTCACATCAACAAACCGCCAGTATTAAACAA
GGTTCTGATATTCCTTATACTGTCTCACGGGGTAAAAAAGAGGCAGCGGCCATTGAGTTCAAAGAAGCGGTGTTGGGGAT
GGAGGTCACACCCAAAATTCTACGTAATGGCAAAATCATCCTAGACCTAAAAATTAGTCAAAATATGCCCGGTATCACTA
TTAAACGCGGTGAGAGTGAAATGTTGCTAATAGATAAACAAGAAATTAAAACACAAGTTACTGTAAACGATGGCGAAACC
ATCGTGCTGGGCGGGATTTTCCAACAAAAAAAACGCCAGAGTGTTAATAAAGTCCCGTTACTGGCCGATATTCCACTATT
AGGCGCGATGTTCAGGCAAGATACTCAACAGCAAAGTCGGCGGGAGTTAGTGATTTTCATTACGCCAAAATTAATCAGTG
CCTGA

Upstream 100 bases:

>100_bases
CTCACCAAATAATGCCTCATCCAGTAATGCCTCATTACCGCGTACCCGCAGCGGGGGGCCAGTCACCCTGGAATTTCAGG
ATGCGCCGGTCTCCGTCATC

Downstream 100 bases:

>100_bases
GCCTTGTAAGATGTCATTTTATGAAAACAGGGCAGTCTTGGTGACTTTCTGCAACTTTTTGTGTGATTGGAGGCTTCTAA
ATTTGACGCTGCGACAGATT

Product: putative outer membrane porin HofQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANL
TLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISSEDLQ
ELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTASIKQ
GSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGET
IVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA

Sequences:

>Translated_374_residues
MQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANL
TLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISSEDLQ
ELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTASIKQ
GSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGET
IVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
>Mature_374_residues
MQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANL
TLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISSEDLQ
ELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTASIKQ
GSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGET
IVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA

Specific function: Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=381, Percent_Identity=48.2939632545932, Blast_Score=350, Evalue=6e-98,
Organism=Escherichia coli, GI87082242, Length=292, Percent_Identity=28.0821917808219, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 41172; Mature: 41172

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQE
CCCHHHHHHEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHH
IQERQQRTKQQAAPEALANLTLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLL
HHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEE
IRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISSEDLQELGVRWGMGEGKGNTALRIN
EEECCHHHHHHHHHHEECCCCHHHEEEEEEEEEECCHHHHHHHHEECCCCCCCCEEEEEE
DFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTASIKQ
EEEEECCCCCCHHHHCCHHHHHCCEEEEEEHHHCCCCCCEEEEECCCEEECCCHHHCCCC
GSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESE
CCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHCCEEEEEEEECCCCCCEEEECCCCC
MLLIDKQEIKTQVTVNDGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSR
EEEEEHHHCEEEEEECCCCEEEEEHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCC
RELVIFITPKLISA
CCEEEEECCHHHCC
>Mature Secondary Structure
MQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQE
CCCHHHHHHEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHH
IQERQQRTKQQAAPEALANLTLALQYANAEQVADSLDPLQGGLLSPLGSVVADKRTNTLL
HHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEE
IRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTISSEDLQELGVRWGMGEGKGNTALRIN
EEECCHHHHHHHHHHEECCCCHHHEEEEEEEEEECCHHHHHHHHEECCCCCCCCEEEEEE
DFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQTASIKQ
EEEEECCCCCCHHHHCCHHHHHCCEEEEEEHHHCCCCCCEEEEECCCEEECCCHHHCCCC
GSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESE
CCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHCCEEEEEEEECCCCCCEEEECCCCC
MLLIDKQEIKTQVTVNDGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSR
EEEEEHHHCEEEEEECCCCEEEEEHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCC
RELVIFITPKLISA
CCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1309529; 9278503; 7901733 [H]