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The map label for this gene is bioH [H]

Identifier: 22127777

GI number: 22127777

Start: 4363390

End: 4363512

Strand: Direct

Name: bioH [H]

Synonym: y3907

Alternate gene names: 22127777

Gene position: 4363390-4363512 (Clockwise)

Preceding gene: 22127775

Following gene: 22127778

Centisome position: 94.84

GC content: 47.97

Gene sequence:

>123_bases
ATGGCAACAGGATATTACTGTATGAAGCAGCTTTATTGGTACACCTGCGGTGAAGGCGATTGCGATCTTGTGTTGTTGCA
CGGATGGGGGCTGAATAGCGGGGGTATGGCATTGCATTATTGA

Upstream 100 bases:

>100_bases
TGGCATAGCCAACACTGGCTAACGGTTGTTAGCATAGGTATCTTCCTTGATTTTAGTGCCCTTTTAGTGAGCTAAATCAC
CTGACAGGGCTGTTATTCTT

Downstream 100 bases:

>100_bases
TCGACTTGCGCCGCATTTTCGTCTGCATTTGGTGGACCTGCCGGGTTATGGGCGCAGCCAAGATTATGGTGCGATGTCAC
TGGCTGACATGGCCGAGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 40; Mature: 39

Protein sequence:

>40_residues
MATGYYCMKQLYWYTCGEGDCDLVLLHGWGLNSGGMALHY

Sequences:

>Translated_40_residues
MATGYYCMKQLYWYTCGEGDCDLVLLHGWGLNSGGMALHY
>Mature_39_residues
ATGYYCMKQLYWYTCGEGDCDLVLLHGWGLNSGGMALHY

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 4522; Mature: 4391

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.5 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
15.0 %Cys+Met (Translated Protein)
7.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
12.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGYYCMKQLYWYTCGEGDCDLVLLHGWGLNSGGMALHY
CCCHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCEEEEC
>Mature Secondary Structure 
ATGYYCMKQLYWYTCGEGDCDLVLLHGWGLNSGGMALHY
CCHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA