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The map label for this gene is yhjH [H]

Identifier: 22127711

GI number: 22127711

Start: 4274445

End: 4275290

Strand: Direct

Name: yhjH [H]

Synonym: y3841

Alternate gene names: 22127711

Gene position: 4274445-4275290 (Clockwise)

Preceding gene: 22127708

Following gene: 22127713

Centisome position: 92.91

GC content: 48.82

Gene sequence:

>846_bases
ATGGCGACTAAACAGATGATGACCAACAGAATATCAGCCTTACTTGCGCCATCCTTTGCCGCGATTGATCAGACAAAGAG
GCTTGATCAGACAAGGAAGTTCGGTCAGATCAAAGAAATTGAACGAACAAAAGGACAGAGCTTCTGGCGGCAATGTCAGC
GGCGGTATACTTTTCAACCCATTTATCGCACATCCGGGGCGTTGCTGGCGATTGAGTTGCTCACGGCGGTTTTTCACCCC
TCAGCACCGGAGACCCGTTTATCACCGGAAGATTACTTCAGCGCTATCAGCACGGGTGCCCGTCTGGATGTGGTGCTCGA
GCAGTTGAATATGGTTAAGCAGTGGCATCAGATATTTGTTCATCACTCGGTATTGGTATCGATCAATATTGATGGTCAGG
TATTGGTGGCGATGCAGGAGGATCACGCGGCCAAGCGGCTGATTGATGCGATGCCTTATATCCGTTTTGAGTTACTTGAA
CACGTTGATACTTCACTGGATACCCCCTTCGCGCGTATTGCCGAAGCTGATCGACTCTGGTTGGACGATTTCGGTAGCGG
GCTGGCGAATTTCACCTCATTCATTAGCTGGCGCTATGAATATATTAAAGTGGCCAGAGATCTGTTTACTGTATTGCAAG
ACAGTGAGGCAGGAAATCGGCTCTTTTTCACACTAGTCACATTAATGGATCGCTACAGTAAAGGCGTTATTGTTGAAGGG
GTAGAAACTTCTCAAGAATGGGCGATGGTGCAGCGTTCCGATGCCGTTGCTGCGCAGGGCTATTATCTTTCTCGACCGGC
ATCATTTGATGGGTTACAAGCACTCCCGATGCTGTTTTGCGGCTAA

Upstream 100 bases:

>100_bases
GCCTGAGTCGATAACATCAGCAGAAGGAAAACCGTTTACTACAGGATGTCAGCATGACAGCGATAGCCCGCCCCGCCATT
GCTGTTTGGTACCCTGAAAC

Downstream 100 bases:

>100_bases
CGCTCCCTAAGGCGATAATGATCGCCTTTCATCTTCTCCTGCCTGCCTCACGGGTTCTAACGGTATAACCGGATTTTCAC
TGTCTAAATAGTGGATTCTG

Product: EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MATKQMMTNRISALLAPSFAAIDQTKRLDQTRKFGQIKEIERTKGQSFWRQCQRRYTFQPIYRTSGALLAIELLTAVFHP
SAPETRLSPEDYFSAISTGARLDVVLEQLNMVKQWHQIFVHHSVLVSINIDGQVLVAMQEDHAAKRLIDAMPYIRFELLE
HVDTSLDTPFARIAEADRLWLDDFGSGLANFTSFISWRYEYIKVARDLFTVLQDSEAGNRLFFTLVTLMDRYSKGVIVEG
VETSQEWAMVQRSDAVAAQGYYLSRPASFDGLQALPMLFCG

Sequences:

>Translated_281_residues
MATKQMMTNRISALLAPSFAAIDQTKRLDQTRKFGQIKEIERTKGQSFWRQCQRRYTFQPIYRTSGALLAIELLTAVFHP
SAPETRLSPEDYFSAISTGARLDVVLEQLNMVKQWHQIFVHHSVLVSINIDGQVLVAMQEDHAAKRLIDAMPYIRFELLE
HVDTSLDTPFARIAEADRLWLDDFGSGLANFTSFISWRYEYIKVARDLFTVLQDSEAGNRLFFTLVTLMDRYSKGVIVEG
VETSQEWAMVQRSDAVAAQGYYLSRPASFDGLQALPMLFCG
>Mature_280_residues
ATKQMMTNRISALLAPSFAAIDQTKRLDQTRKFGQIKEIERTKGQSFWRQCQRRYTFQPIYRTSGALLAIELLTAVFHPS
APETRLSPEDYFSAISTGARLDVVLEQLNMVKQWHQIFVHHSVLVSINIDGQVLVAMQEDHAAKRLIDAMPYIRFELLEH
VDTSLDTPFARIAEADRLWLDDFGSGLANFTSFISWRYEYIKVARDLFTVLQDSEAGNRLFFTLVTLMDRYSKGVIVEGV
ETSQEWAMVQRSDAVAAQGYYLSRPASFDGLQALPMLFCG

Specific function: A bis-(3'-5') cyclic diguanylic acid (c-di-GMP) phosphodiesterase involved in regulating the levels of c-di-GMP that control cell motility (the flagella) and adhesion (adhesive curli fimbriae). The YhjH effect on flagella is controlled via the c-di-GMP-bi

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87082280, Length=234, Percent_Identity=49.1452991452991, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 32049; Mature: 31918

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKQMMTNRISALLAPSFAAIDQTKRLDQTRKFGQIKEIERTKGQSFWRQCQRRYTFQP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHCCCCCH
IYRTSGALLAIELLTAVFHPSAPETRLSPEDYFSAISTGARLDVVLEQLNMVKQWHQIFV
HHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HHSVLVSINIDGQVLVAMQEDHAAKRLIDAMPYIRFELLEHVDTSLDTPFARIAEADRLW
HHEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LDDFGSGLANFTSFISWRYEYIKVARDLFTVLQDSEAGNRLFFTLVTLMDRYSKGVIVEG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEC
VETSQEWAMVQRSDAVAAQGYYLSRPASFDGLQALPMLFCG
CCCHHHHHHHHHCCCHHHCCEEECCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
ATKQMMTNRISALLAPSFAAIDQTKRLDQTRKFGQIKEIERTKGQSFWRQCQRRYTFQP
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHCCCCCH
IYRTSGALLAIELLTAVFHPSAPETRLSPEDYFSAISTGARLDVVLEQLNMVKQWHQIFV
HHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HHSVLVSINIDGQVLVAMQEDHAAKRLIDAMPYIRFELLEHVDTSLDTPFARIAEADRLW
HHEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LDDFGSGLANFTSFISWRYEYIKVARDLFTVLQDSEAGNRLFFTLVTLMDRYSKGVIVEG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEC
VETSQEWAMVQRSDAVAAQGYYLSRPASFDGLQALPMLFCG
CCCHHHHHHHHHCCCHHHCCEEECCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]