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The map label for this gene is dppB [H]

Identifier: 22127697

GI number: 22127697

Start: 4257574

End: 4258521

Strand: Direct

Name: dppB [H]

Synonym: y3826

Alternate gene names: 22127697

Gene position: 4257574-4258521 (Clockwise)

Preceding gene: 22127696

Following gene: 22127698

Centisome position: 92.54

GC content: 53.59

Gene sequence:

>948_bases
ATGTTGCAGTTCATACTCCGACGTTTGGGGTTAGTTATCCCAACGTTTATCGGCATTACTTTGCTGACCTTTGCTTTTGT
CCATATGATCCCCGGTGACCCGGTGACCATCATGGCGGGGGAACGCGGTATCTCTGCCGAGCGTCATGCTCAAGTCATGG
CGGAAATGGGGCTGGACAAGCCTCTCTATCAACAATATTTCCGCTATGTAAATGGCGTTTTACATGGTGACCTTGGCATT
TCGCTGAAAAGCCGTATTGCGGTATGGGATGAGTTTGTCCCGCGCTTTAAAGCAACACTGGAACTGGGGATCTGCGCGAT
GCTGTTTGCTATCGCAGTCGGCATTCCGGTTGGTGTGCTGGCAGCAGTGAAACGCGGTTCAATATTTGATCACACCGCCG
TGGGGATCTCCCTTACCGGCTATTCGATGCCTATCTTCTGGTGGGGCATCATGCTGATCATGCTGGTCTCGGTGCAATGG
GACCTGACCCCGGTTTCCGGGCGTGTCAGCGATACCGTGTTCCTTGATGACAGCCTGCCTCTGACGGGGTTTATGTTGAT
TGATACCCTCATCTGGGGGGAACCTGACGATTTTAAAGATGCGGTAATGCATATGATTTTACCGGCAATCGTCTTGGGGA
CTATTCCCTTGGCGGTGATCGTGCGTATGACTCGTTCCTCCATGTTGGAAGTGTTGGGGGAGGATTATATCCGTACTGCG
CGGGCCAAAGGGCTGAGCCGCATGCGGGTGATTGTGGTCCATGCGTTACGCAATGCCTTGCTGCCTGTCATCACGGTGAT
TGGTTTGCAGGTTGGTACCATGCTGGCTGGGGCTATCTTGACGGAAACCATCTTCTCGTGGCCGGGTCTGGGTCGTTGGC
TGATGGATGCATTGCAACGCCGTGATTACCCTGTGGTGCAGGGGGGGTGTTGCTGGTCGCGATCATGA

Upstream 100 bases:

>100_bases
CTGTCGCTCAACATCGACGAATAAAATCGCTTATTTGGAGAGGTTTAATAAGCCAGGTTGCCTATGAGCAGCCCGGCATT
CTACACAGAGAGTTCGGGAT

Downstream 100 bases:

>100_bases
TTATTTTAGTTAACTTGCTGGTAGATGTGCTCTATGGCGTAGTTAACCCGCGTATTCGTCACAAGAAATAAGGGGCGCAG
AATGTCTCAACTTATTGAGT

Product: dipeptide transport system inner membrane permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAQVMAEMGLDKPLYQQYFRYVNGVLHGDLGI
SLKSRIAVWDEFVPRFKATLELGICAMLFAIAVGIPVGVLAAVKRGSIFDHTAVGISLTGYSMPIFWWGIMLIMLVSVQW
DLTPVSGRVSDTVFLDDSLPLTGFMLIDTLIWGEPDDFKDAVMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLSRMRVIVVHALRNALLPVITVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQRRDYPVVQGGCCWSRS

Sequences:

>Translated_315_residues
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAQVMAEMGLDKPLYQQYFRYVNGVLHGDLGI
SLKSRIAVWDEFVPRFKATLELGICAMLFAIAVGIPVGVLAAVKRGSIFDHTAVGISLTGYSMPIFWWGIMLIMLVSVQW
DLTPVSGRVSDTVFLDDSLPLTGFMLIDTLIWGEPDDFKDAVMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLSRMRVIVVHALRNALLPVITVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQRRDYPVVQGGCCWSRS
>Mature_315_residues
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAQVMAEMGLDKPLYQQYFRYVNGVLHGDLGI
SLKSRIAVWDEFVPRFKATLELGICAMLFAIAVGIPVGVLAAVKRGSIFDHTAVGISLTGYSMPIFWWGIMLIMLVSVQW
DLTPVSGRVSDTVFLDDSLPLTGFMLIDTLIWGEPDDFKDAVMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLSRMRVIVVHALRNALLPVITVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQRRDYPVVQGGCCWSRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=310, Percent_Identity=87.4193548387097, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1787761, Length=291, Percent_Identity=44.3298969072165, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1787053, Length=308, Percent_Identity=39.9350649350649, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787550, Length=251, Percent_Identity=39.4422310756972, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=34.2019543973941, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1789888, Length=311, Percent_Identity=33.4405144694534, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1788504, Length=348, Percent_Identity=29.0229885057471, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34787; Mature: 34787

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAQVMAEMGLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PLYQQYFRYVNGVLHGDLGISLKSRIAVWDEFVPRFKATLELGICAMLFAIAVGIPVGVL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKRGSIFDHTAVGISLTGYSMPIFWWGIMLIMLVSVQWDLTPVSGRVSDTVFLDDSLP
HHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
LTGFMLIDTLIWGEPDDFKDAVMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKGLSRMRVIVVHALRNALLPVITVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RDYPVVQGGCCWSRS
CCCCEEECCCCCCCC
>Mature Secondary Structure
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAQVMAEMGLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PLYQQYFRYVNGVLHGDLGISLKSRIAVWDEFVPRFKATLELGICAMLFAIAVGIPVGVL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKRGSIFDHTAVGISLTGYSMPIFWWGIMLIMLVSVQWDLTPVSGRVSDTVFLDDSLP
HHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
LTGFMLIDTLIWGEPDDFKDAVMHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKGLSRMRVIVVHALRNALLPVITVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RDYPVVQGGCCWSRS
CCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]