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The map label for this gene is fct [H]

Identifier: 22127219

GI number: 22127219

Start: 3682777

End: 3685014

Strand: Direct

Name: fct [H]

Synonym: y3343

Alternate gene names: 22127219

Gene position: 3682777-3685014 (Clockwise)

Preceding gene: 22127218

Following gene: 22127234

Centisome position: 80.05

GC content: 52.77

Gene sequence:

>2238_bases
TTGCCGACGTTTCACCACAGGATACGCTGCAAACTATTTACCAGCAGTTTTTGCCGCTGGATTTCACAGGAACTTTCTGG
AGCCATTTGGATAATGAATAAAATAAACATGTTCATGCTATCCACGTTCATGCGATCCATGTTCATGCGATCTACGTTGA
TACCCTCTACGTTCATACTGTCCACACTACTGCTGCCGGCTGTCGTGTTGGCAGAAGATACGATAATCGTTGAGAGAAAT
AGATCGCAAACTGATAGCTATCAAGCGACCACCAGCGTGACAGCCAATCGATCGCCAGCCAACATTATCGATACCCCGCA
AAACGTGACTGTCGTGACACATCCGGTGTTGGAAGATTATGATGTGACCAATCTTGGCGAGGCGCTTTATTTTGTCAGCG
GGATTACCCAATCCAACACGCTGGGTGGCACGCAAGATGCGCTGATTAAGCGCGGTTTCGGCAATAACCGTGACGGCTCA
ATTCTGCACGATGGCATACGCTCAATTCAGGCACGTAACTTCACGCCCACCAGCGAACGCGTCGAGGTGCTGAAAGGCCC
CTCCTCCATGCTATACGGTATGAATGAACCGGGTGGGCTGATCAATGTGATCAGCAAAAAGCCACAACTCGATCCCCATG
TGCATTTGGAAGCCAACGCCAGTAGTTTCAAGGGTGGCGGTGGCCAACTTGATGTAACCGGCCCCTTGGGGGAATCCGGC
TTTGCCGGGAGGCTGATTATCGATCATCAGGAGACCGATTACTGGCGTAACTTTGGCCGTAACCGCCAGACTGTGGTCGC
GCCATCGCTTGACTGGTACGGTGAAAACACCACCGTACACCTCGCTTGGGAACGAATGGAGTATTTGGTACCGTTCGACC
GTGGCACGGTGATTGACCCACGCACTGGCAAACCCGTCGACACGCCGCGTGATCGCCGTTTCGACGAGAGCTATAACGCC
ACCCGCGGCGATCAAGACACCGTCACGTTTAGCATCAACCACGATCTGAACGAGTTCTGGTCCACACAGCTAAATTATGC
TTTCAGCCGCAATAGCTATAGTGATAATCAGGCACGCGCCACTGCATTTAACGCTGAAACCGGCGTATTGACCCGCCAGT
CGGATGCTACCGCTAACGCCAAGAGCCATTCGCAGGCGGTGCAGTGGGTAGTCAATGGTGATCTCGATTGGGGTTTCACT
CATCACCAACTGATGTTTGGTATCGATTATGAAGCCCGCCGCGTTTTCCGTGGCGACATGATACGCGGCAGCAAAAACAA
CGGGTTTAATGTCTATGACCCAATTTATGGCACTCTGCCCCCATCCACAGCCGTCAGTGCTGCTGATAGCGATCAGCGGG
AAAATATCGATAGCCGCGCGCTGTTCATTCAAGACTCGATGCGCCTAAACGAGCACTGGCTATTACTCGGTGGCCTGCGC
TACGACAGCTTCGATGTGATGGCAGGTAAAGGCCGCCCATTCAAAAAGAATACCGACAGTTCCGATAGCCGCTTGGTGCC
GCGCGCCGGGGTGGTTTACAACCTGAACGACTGGTCAAGCCTATACGTCAGCTACACCGAGTCCTTTAAACCGAATGTCT
CTATCGCCACCGCCATTGATGCGTTACCCCCCGAATACGGTAAATCGTGGGAGGCGGGCTACAAAATTGATATCAACAAC
CGTGTAACCGGTACGCTCGCGGTCTACGATATCCATAAACGTAACATTATGGTCAGCGAGCTGGTAGACGGCGAAACAGT
CACACGTACCGCCGGTAAGGCGCGTTCACGCGGCCTGGAACTGGATATGGCTGGCAAAGTGACCGACTCACTGAGTCTCA
TTGGCAGCTATGCCTATACCGATGCACGCCTGACTGAAGACCCGGATAACAATGGTAACGACCTACCCAACGTGGCACGC
CACACTGCGGCACTGTTTCTGAGCCGGGACTTCGGCAGTACGTCATTGATTTCAGGCGATGAAGTGAAAGCAGGTATTGG
CGCACGCTATGTCGGGAAACGTGCTGGCGACGCCGCCAACAGTTTCTGGCTAGATAACTACACCGTAGCGGACGCGTTTA
TCGCCTGGAAGATGCCGCTCTCCGGCTATCAACTCAAATGGCAGCTTAATGTGAAAAACCTGTTCGATAAGACGTACTAT
CCGTCGAGCGCTAACAACCTGCGTATCGCTATCGGCGAACCACGTCAGGTTGTGTTGCAGGGCAGTATCGATTTCTAA

Upstream 100 bases:

>100_bases
CAAAATGGTCACGCTTGGGGGTTGTGGCACAACTTCTATTTAAGCCCGCTGCATGTAGTGGCGGCGGAGTTTTTCGCTAA
AACGCTTTATCCACACCTGT

Downstream 100 bases:

>100_bases
CAAACAGAGGGCATTGTTACTGAAGAGGGTAATGTTACTGCTGCCCTCTGTTTAGATCAACGTCCTGACCTAGCCCCAAA
AATCAGGCTTTACTCCGCGA

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 745; Mature: 744

Protein sequence:

>745_residues
MPTFHHRIRCKLFTSSFCRWISQELSGAIWIMNKINMFMLSTFMRSMFMRSTLIPSTFILSTLLLPAVVLAEDTIIVERN
RSQTDSYQATTSVTANRSPANIIDTPQNVTVVTHPVLEDYDVTNLGEALYFVSGITQSNTLGGTQDALIKRGFGNNRDGS
ILHDGIRSIQARNFTPTSERVEVLKGPSSMLYGMNEPGGLINVISKKPQLDPHVHLEANASSFKGGGGQLDVTGPLGESG
FAGRLIIDHQETDYWRNFGRNRQTVVAPSLDWYGENTTVHLAWERMEYLVPFDRGTVIDPRTGKPVDTPRDRRFDESYNA
TRGDQDTVTFSINHDLNEFWSTQLNYAFSRNSYSDNQARATAFNAETGVLTRQSDATANAKSHSQAVQWVVNGDLDWGFT
HHQLMFGIDYEARRVFRGDMIRGSKNNGFNVYDPIYGTLPPSTAVSAADSDQRENIDSRALFIQDSMRLNEHWLLLGGLR
YDSFDVMAGKGRPFKKNTDSSDSRLVPRAGVVYNLNDWSSLYVSYTESFKPNVSIATAIDALPPEYGKSWEAGYKIDINN
RVTGTLAVYDIHKRNIMVSELVDGETVTRTAGKARSRGLELDMAGKVTDSLSLIGSYAYTDARLTEDPDNNGNDLPNVAR
HTAALFLSRDFGSTSLISGDEVKAGIGARYVGKRAGDAANSFWLDNYTVADAFIAWKMPLSGYQLKWQLNVKNLFDKTYY
PSSANNLRIAIGEPRQVVLQGSIDF

Sequences:

>Translated_745_residues
MPTFHHRIRCKLFTSSFCRWISQELSGAIWIMNKINMFMLSTFMRSMFMRSTLIPSTFILSTLLLPAVVLAEDTIIVERN
RSQTDSYQATTSVTANRSPANIIDTPQNVTVVTHPVLEDYDVTNLGEALYFVSGITQSNTLGGTQDALIKRGFGNNRDGS
ILHDGIRSIQARNFTPTSERVEVLKGPSSMLYGMNEPGGLINVISKKPQLDPHVHLEANASSFKGGGGQLDVTGPLGESG
FAGRLIIDHQETDYWRNFGRNRQTVVAPSLDWYGENTTVHLAWERMEYLVPFDRGTVIDPRTGKPVDTPRDRRFDESYNA
TRGDQDTVTFSINHDLNEFWSTQLNYAFSRNSYSDNQARATAFNAETGVLTRQSDATANAKSHSQAVQWVVNGDLDWGFT
HHQLMFGIDYEARRVFRGDMIRGSKNNGFNVYDPIYGTLPPSTAVSAADSDQRENIDSRALFIQDSMRLNEHWLLLGGLR
YDSFDVMAGKGRPFKKNTDSSDSRLVPRAGVVYNLNDWSSLYVSYTESFKPNVSIATAIDALPPEYGKSWEAGYKIDINN
RVTGTLAVYDIHKRNIMVSELVDGETVTRTAGKARSRGLELDMAGKVTDSLSLIGSYAYTDARLTEDPDNNGNDLPNVAR
HTAALFLSRDFGSTSLISGDEVKAGIGARYVGKRAGDAANSFWLDNYTVADAFIAWKMPLSGYQLKWQLNVKNLFDKTYY
PSSANNLRIAIGEPRQVVLQGSIDF
>Mature_744_residues
PTFHHRIRCKLFTSSFCRWISQELSGAIWIMNKINMFMLSTFMRSMFMRSTLIPSTFILSTLLLPAVVLAEDTIIVERNR
SQTDSYQATTSVTANRSPANIIDTPQNVTVVTHPVLEDYDVTNLGEALYFVSGITQSNTLGGTQDALIKRGFGNNRDGSI
LHDGIRSIQARNFTPTSERVEVLKGPSSMLYGMNEPGGLINVISKKPQLDPHVHLEANASSFKGGGGQLDVTGPLGESGF
AGRLIIDHQETDYWRNFGRNRQTVVAPSLDWYGENTTVHLAWERMEYLVPFDRGTVIDPRTGKPVDTPRDRRFDESYNAT
RGDQDTVTFSINHDLNEFWSTQLNYAFSRNSYSDNQARATAFNAETGVLTRQSDATANAKSHSQAVQWVVNGDLDWGFTH
HQLMFGIDYEARRVFRGDMIRGSKNNGFNVYDPIYGTLPPSTAVSAADSDQRENIDSRALFIQDSMRLNEHWLLLGGLRY
DSFDVMAGKGRPFKKNTDSSDSRLVPRAGVVYNLNDWSSLYVSYTESFKPNVSIATAIDALPPEYGKSWEAGYKIDINNR
VTGTLAVYDIHKRNIMVSELVDGETVTRTAGKARSRGLELDMAGKVTDSLSLIGSYAYTDARLTEDPDNNGNDLPNVARH
TAALFLSRDFGSTSLISGDEVKAGIGARYVGKRAGDAANSFWLDNYTVADAFIAWKMPLSGYQLKWQLNVKNLFDKTYYP
SSANNLRIAIGEPRQVVLQGSIDF

Specific function: Involved in the initial step of iron uptake by binding chrysobactin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=756, Percent_Identity=26.8518518518519, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787344, Length=771, Percent_Identity=25.1621271076524, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1787723, Length=739, Percent_Identity=23.9512855209743, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787024, Length=238, Percent_Identity=31.0924369747899, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1790743, Length=323, Percent_Identity=24.7678018575851, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 83018; Mature: 82887

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFHHRIRCKLFTSSFCRWISQELSGAIWIMNKINMFMLSTFMRSMFMRSTLIPSTFIL
CCCCCCEEEEEEHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHH
STLLLPAVVLAEDTIIVERNRSQTDSYQATTSVTANRSPANIIDTPQNVTVVTHPVLEDY
HHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
DVTNLGEALYFVSGITQSNTLGGTQDALIKRGFGNNRDGSILHDGIRSIQARNFTPTSER
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
VEVLKGPSSMLYGMNEPGGLINVISKKPQLDPHVHLEANASSFKGGGGQLDVTGPLGESG
HHHHCCCHHHEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCC
FAGRLIIDHQETDYWRNFGRNRQTVVAPSLDWYGENTTVHLAWERMEYLVPFDRGTVIDP
CCCEEEEECCCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECEEEEEECCCCCEECC
RTGKPVDTPRDRRFDESYNATRGDQDTVTFSINHDLNEFWSTQLNYAFSRNSYSDNQARA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCEEEECCCCCCCCCEE
TAFNAETGVLTRQSDATANAKSHSQAVQWVVNGDLDWGFTHHQLMFGIDYEARRVFRGDM
EEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEECCHHHHHHHHCCE
IRGSKNNGFNVYDPIYGTLPPSTAVSAADSDQRENIDSRALFIQDSMRLNEHWLLLGGLR
EECCCCCCCEEECCCCCCCCCCHHCCCCCCHHHCCCCCEEEEEECCCCCCCEEEEEECCE
YDSFDVMAGKGRPFKKNTDSSDSRLVPRAGVVYNLNDWSSLYVSYTESFKPNVSIATAID
ECCEEEEECCCCCCCCCCCCCCCEECCCCCEEEECCCCCEEEEEEECCCCCCEEEEEHHH
ALPPEYGKSWEAGYKIDINNRVTGTLAVYDIHKRNIMVSELVDGETVTRTAGKARSRGLE
CCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEHHCCCCCEECCCCHHHHCCCE
LDMAGKVTDSLSLIGSYAYTDARLTEDPDNNGNDLPNVARHTAALFLSRDFGSTSLISGD
EEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHEEEEEECCCCCCEEECCC
EVKAGIGARYVGKRAGDAANSFWLDNYTVADAFIAWKMPLSGYQLKWQLNVKNLFDKTYY
CCCCCCCHHHHCCCCCCCCCCEEECCEEEEEEEEEEECCCCCEEEEEEECHHHHHHCCCC
PSSANNLRIAIGEPRQVVLQGSIDF
CCCCCCEEEEECCCEEEEEEECCCC
>Mature Secondary Structure 
PTFHHRIRCKLFTSSFCRWISQELSGAIWIMNKINMFMLSTFMRSMFMRSTLIPSTFIL
CCCCCEEEEEEHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHH
STLLLPAVVLAEDTIIVERNRSQTDSYQATTSVTANRSPANIIDTPQNVTVVTHPVLEDY
HHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
DVTNLGEALYFVSGITQSNTLGGTQDALIKRGFGNNRDGSILHDGIRSIQARNFTPTSER
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
VEVLKGPSSMLYGMNEPGGLINVISKKPQLDPHVHLEANASSFKGGGGQLDVTGPLGESG
HHHHCCCHHHEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCC
FAGRLIIDHQETDYWRNFGRNRQTVVAPSLDWYGENTTVHLAWERMEYLVPFDRGTVIDP
CCCEEEEECCCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECEEEEEECCCCCEECC
RTGKPVDTPRDRRFDESYNATRGDQDTVTFSINHDLNEFWSTQLNYAFSRNSYSDNQARA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCEEEECCCCCCCCCEE
TAFNAETGVLTRQSDATANAKSHSQAVQWVVNGDLDWGFTHHQLMFGIDYEARRVFRGDM
EEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEECCHHHHHHHHCCE
IRGSKNNGFNVYDPIYGTLPPSTAVSAADSDQRENIDSRALFIQDSMRLNEHWLLLGGLR
EECCCCCCCEEECCCCCCCCCCHHCCCCCCHHHCCCCCEEEEEECCCCCCCEEEEEECCE
YDSFDVMAGKGRPFKKNTDSSDSRLVPRAGVVYNLNDWSSLYVSYTESFKPNVSIATAID
ECCEEEEECCCCCCCCCCCCCCCEECCCCCEEEECCCCCEEEEEEECCCCCCEEEEEHHH
ALPPEYGKSWEAGYKIDINNRVTGTLAVYDIHKRNIMVSELVDGETVTRTAGKARSRGLE
CCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEHHCCCCCEECCCCHHHHCCCE
LDMAGKVTDSLSLIGSYAYTDARLTEDPDNNGNDLPNVARHTAALFLSRDFGSTSLISGD
EEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHEEEEEECCCCCCEEECCC
EVKAGIGARYVGKRAGDAANSFWLDNYTVADAFIAWKMPLSGYQLKWQLNVKNLFDKTYY
CCCCCCCHHHHCCCCCCCCCCEEECCEEEEEEEEEEECCCCCEEEEEEECHHHHHHCCCC
PSSANNLRIAIGEPRQVVLQGSIDF
CCCCCCEEEEECCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8576065 [H]