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The map label for this gene is tsr [H]

Identifier: 22127066

GI number: 22127066

Start: 3511963

End: 3513663

Strand: Reverse

Name: tsr [H]

Synonym: y3190

Alternate gene names: 22127066

Gene position: 3513663-3511963 (Counterclockwise)

Preceding gene: 22127067

Following gene: 22127063

Centisome position: 76.37

GC content: 44.97

Gene sequence:

>1701_bases
GTGAATAACATGTTTTCACGCATGAATTATGTTGTTAAAAAATATTTTGGCTACATTATGAGTAAACTTTCGCTTTCTGA
ATCTAGATTGGGAATATTATTTGGTTTTACTTTAGTGATTAGTCTATTTTCTTTGTTGCAGATCTTCTCCATAGGTTATT
TATCTCATATTTTAAAGAGTACCAAAGCGAATGTAGAGATAACGCACCGTAATCATCAACAAGAGGCGTTGATGGATCGT
GCGCGGATGGAACTATTAATTGCCAGTGACAAGCTTAATCGTGCGGGTATCTATTATATGGAAGATAAAGAGACCGGCTC
CGAAGGCAGTTGGCAAAGTCTTCTCAATGAGGCATTGCAGTCATTGCAGCAATCTCAGGACAGCTATCTGCAGTTGCAGG
CGGTTTCCGCCCAAGACAGTAGACAAGAATTGAATGAACTTAAGGAGAGCTACCATCAGTTGTATCAGGGGCTGGCTGAA
ATAGCGCAGGGGTTAGCGCAAAAGCACAATATTGACACCTTCTTTGACGTGCCTATCCAGGGCTTTCAGAGCGACTTCAC
CGAGAAGTACTACCGCTATTTACAGGAAAGTGAAAAGGGCAGCACTGCTATGGATGAGCAGCTCTTGTCCTCACTGTCTT
CAGCTAAACAGATCATTATTGGTGCACTGGCCATATTGTTGGTACTGGCTTTCTCTGCCTGGCTAGGCGTCACCCGTTGG
ATGATTGCGCCCTTAAATCACCTTATCTCACGTATCAATAAGATTGCTGCCGGGGATTTATCACACCGTATTGAAGACAC
GTCTTTTGCTTGCCGAGAAATTAGACAACTCACTTATAGTGTAAGACATATGCAAGAGGGGCTAGTTGCATTGGTTAGCC
AGGTCCGAGGTGGAGCTGAGGTGATCCTGACCGGTGTGAACCAGATTACGGCTGATAACCATCGTCTCTCTGAACAAACG
CACTCACAAACTCAATCATTGGCGGTGACGGCGCAAAGTATGCAGCAGCTTACCGTCAGGGTTAAACAAAACTCCATGAG
TGCCGAGCAGGCGAATCATCTGGTGAATGAAGCTAGAGATACGGCCAGTCAGGGAGGAGAGATGATGTCTAATGTGGTGA
GTTCAATGGCCGATATTTCCACGGGTTCACGGGAGATAAGCGAAATTATTACACTTATTGAGTCGGTTGCTTTTCAGACC
AATATTTTGGCATTAAATGCAGCAATTGAAGCCGCTCATGCGGGTGAACACGGCCGTGGGTTCTCTGTTGTGGCACGTGA
GGTCGGTACATTGTCTCACCAAAGTGGCCATTCAGCACAAAATATTAAGCGCCTTATTCAGCATTCTGCCAACTCAGTTT
CTACGGGGGCCTCGCTGGTTAATCGTTCCGGTGAGAATTTACAGGCTATTATTGATGTGGTGAAGAAAGTCACCGATTTA
ATGGCGGAAATAACTACCGCATCACATTATCAAAGCAAAGGAATTGAGGAGATGGCCGCGCAGGTAGAGATGATTAATGG
CGCAACAAAACAGAATGCAGCATTGGTTGAGCAATCTGCACACGCATCGGAAGTGTTGCAACAGCAGACCTTACAGCTTA
ATCAGTCGGTAGCCCGCTTTCATTTACCTGTAGAAAAATACTCTCCTCTACGATTAGCAAAGGAGAGCACGATTGCTGCT
ATTGATTCACGCGTTAGTTAA

Upstream 100 bases:

>100_bases
TTCATTAACTTCATTTAACTATCACAGCATAATGGTGCTATTGCTGAAATATATCTGTCATAGTGAGCTGCTAGCATGGA
TATCTCTATCATGACCCAAT

Downstream 100 bases:

>100_bases
CCTGTTGATCCAACCCGGTTGATTACCGAAATAATCGCCTGCAGGTACAACTGTCATCTTGCCTGCAGCATCTTGCAATA
TAAATGTTGGGAAGCCGTGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MNNMFSRMNYVVKKYFGYIMSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMDR
ARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAE
IAQGLAQKHNIDTFFDVPIQGFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRW
MIAPLNHLISRINKIAAGDLSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQT
HSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQT
NILALNAAIEAAHAGEHGRGFSVVAREVGTLSHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDL
MAEITTASHYQSKGIEEMAAQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIAA
IDSRVS

Sequences:

>Translated_566_residues
MNNMFSRMNYVVKKYFGYIMSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMDR
ARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAE
IAQGLAQKHNIDTFFDVPIQGFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRW
MIAPLNHLISRINKIAAGDLSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQT
HSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQT
NILALNAAIEAAHAGEHGRGFSVVAREVGTLSHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDL
MAEITTASHYQSKGIEEMAAQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIAA
IDSRVS
>Mature_566_residues
MNNMFSRMNYVVKKYFGYIMSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKSTKANVEITHRNHQQEALMDR
ARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQSLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAE
IAQGLAQKHNIDTFFDVPIQGFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRW
MIAPLNHLISRINKIAAGDLSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAEVILTGVNQITADNHRLSEQT
HSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARDTASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQT
NILALNAAIEAAHAGEHGRGFSVVAREVGTLSHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDL
MAEITTASHYQSKGIEEMAAQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARFHLPVEKYSPLRLAKESTIAA
IDSRVS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=537, Percent_Identity=40.2234636871508, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1788195, Length=545, Percent_Identity=33.7614678899083, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1788194, Length=529, Percent_Identity=35.7277882797732, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=43.2098765432099, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI1789453, Length=328, Percent_Identity=34.7560975609756, Blast_Score=182, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62522; Mature: 62522

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMFSRMNYVVKKYFGYIMSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKS
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKANVEITHRNHQQEALMDRARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQ
HCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
SLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPIQ
HHHHCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCH
GFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRW
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIAPLNHLISRINKIAAGDLSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VILTGVNQITADNHRLSEQTHSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARD
EEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGRG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FSVVAREVGTLSHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MAEITTASHYQSKGIEEMAAQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLPVEKYSPLRLAKESTIAAIDSRVS
CCCHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNMFSRMNYVVKKYFGYIMSKLSLSESRLGILFGFTLVISLFSLLQIFSIGYLSHILKS
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKANVEITHRNHQQEALMDRARMELLIASDKLNRAGIYYMEDKETGSEGSWQSLLNEALQ
HCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
SLQQSQDSYLQLQAVSAQDSRQELNELKESYHQLYQGLAEIAQGLAQKHNIDTFFDVPIQ
HHHHCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCH
GFQSDFTEKYYRYLQESEKGSTAMDEQLLSSLSSAKQIIIGALAILLVLAFSAWLGVTRW
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIAPLNHLISRINKIAAGDLSHRIEDTSFACREIRQLTYSVRHMQEGLVALVSQVRGGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VILTGVNQITADNHRLSEQTHSQTQSLAVTAQSMQQLTVRVKQNSMSAEQANHLVNEARD
EEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TASQGGEMMSNVVSSMADISTGSREISEIITLIESVAFQTNILALNAAIEAAHAGEHGRG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FSVVAREVGTLSHQSGHSAQNIKRLIQHSANSVSTGASLVNRSGENLQAIIDVVKKVTDL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MAEITTASHYQSKGIEEMAAQVEMINGATKQNAALVEQSAHASEVLQQQTLQLNQSVARF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLPVEKYSPLRLAKESTIAAIDSRVS
CCCHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]