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The map label for this gene is ynaJ [H]

Identifier: 22126838

GI number: 22126838

Start: 3260035

End: 3261573

Strand: Direct

Name: ynaJ [H]

Synonym: y2961

Alternate gene names: 22126838

Gene position: 3260035-3261573 (Clockwise)

Preceding gene: 22126837

Following gene: 22126840

Centisome position: 70.86

GC content: 47.24

Gene sequence:

>1539_bases
GTGGCGGTAAACATGAGTAAACAGATTTCAACAAGGCATACGTTGGCTTACGGGAGTGCTAACTTGCTGGGCAGTGGGGC
ACTCGCCATTAGTGGTGCCTGGCTGATGTACTTCTACACAACGTTTTGCGGACTTTCTGTTGTAGAAGCAGCCACTATCT
TTTCAATCGCCAGTATTATTGATGCCATCAGTAACCCGGTAATGGGTTATATCACGGATAACTTCTACAATACCCGTTTG
GGCCGTATCTTCGGGCGTCGTCGCTTCTTTATCTTACTGGGTATCCCACTCGTGTTGGTCTATCCAATGCTGTGGATGAG
TGGTTTTGGTTTCTGGTATTACCTACTGACCTATGCGCTGTTTGAATTAATTTACACCTCCATCATGGTGCCTTATGAAA
CACTGGCTACCGAGATGACAACCGATTTTGCCAAACGCTCTAAACTGACAGGTTCTAAAGCAATCTTCGGCAAAGTAGCG
AACTTCCTGGCCGCTTTCATTCCAGGTCAATTCATTGCAATTTATGGCAAAGATTCCGCAACCCCCTTCTTATATACCGG
TATCGCTTATGGTCTGATTATGTGCTGCGCCATGATTTGGCTTTACAGCTCATCATGGGAGCGTCCAGCCAGTGAAGTGG
TCAGGGAAACCACCAGTAGTTTAGGTCAGGCACTGAAAAAGCTGTGTGTTGATATGGCATCGACCTTCCATCTGCGCATT
TTCCGCAAGCATCTGGGGATGTATCTGTTCGGTTTTGGTGCTGAATGGTTGTTCGCATCCGCATTTACCTACTTTATTAT
TTTTGGCTTGGGACAAGATGCCGCATTGGTTTCGCAGCTCAATAGCTTCAGTTCGATTATGCAGCTCATCTCCACCGCTA
TTTTTATTGGCATCTGCGTAAAAATGGGTTTCGCTCGTCCCTTCCGTATTGCTCTGCAAGTGGTGATTGTCAGCGTGGTT
GCCTACGCAGCACTGTATTTCACCGGTTGGTCTGAAACCACGACCGTTATCGTCTTATTCTGCATTACCGCTGTTTTCGG
TTTAAGTACTGGTGGGATCTACTATATTCCATGGACAGTTTATACCTTCCTGGCCGATGTAGACGAAGTCTTGACCGGGC
GTCGCCGTGAAGGAATTTATGCTGGCGCGATGACATTCGCCGGGAAAATGGTACGTTCGATTATTGTCTTTGCCATGGGC
TGGACGTTAAGCCGCTTTGGTTTTGTTTCTGGTCAATCCAGTCAGCCAGAAATTGCTGTGCAAGCCATCGTGGGTGTCTT
TGCCATAGGGGTTATCTCACTGGCATTAGTTGCTATTTACTACACCACACAGATGAAACTGGATCGCAAAAATCACAGCA
TTTTACTGGAAGAAATTGAGCGTATTAAAAATGGCGGTGCCATGGCAGATATCCCCGCTCATGCCAGAGCCGTCGCGGAA
GAACTGACGGGGTGGAAATATGAACAATGTTGGGGCAATAACCCCCTCGGCGTCAAAGAGTCGCCAACCGTCATACCCAA
ACCGGTTACTGAAAGTTAA

Upstream 100 bases:

>100_bases
TAAAAATCTTTTTCGTGATCTCCAACTCATTTTTATAAACGCTATACCGCTATAAAGAAAACAGTTATTCATTATAAATG
AAACATTGTTTTAATTTGAG

Downstream 100 bases:

>100_bases
TTAATTTCTGGTCGTGACCACAAACCGCACCGGTCCCGCCAGTGCGGTTTTTGCTTCTCCCTTCCCTGAACATGAATGGG
TAGATAAAATATCGGCGTTG

Product: putative transport protein

Products: Proton [Cytoplasm]; Glucuronides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAVNMSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRL
GRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVA
NFLAAFIPGQFIAIYGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRI
FRKHLGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVV
AYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMG
WTLSRFGFVSGQSSQPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAE
ELTGWKYEQCWGNNPLGVKESPTVIPKPVTES

Sequences:

>Translated_512_residues
MAVNMSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRL
GRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVA
NFLAAFIPGQFIAIYGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRI
FRKHLGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVV
AYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMG
WTLSRFGFVSGQSSQPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAE
ELTGWKYEQCWGNNPLGVKESPTVIPKPVTES
>Mature_511_residues
AVNMSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLG
RIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVAN
FLAAFIPGQFIAIYGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIF
RKHLGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVVA
YAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGW
TLSRFGFVSGQSSQPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEE
LTGWKYEQCWGNNPLGVKESPTVIPKPVTES

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787902, Length=476, Percent_Identity=21.6386554621849, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786466, Length=475, Percent_Identity=22.5263157894737, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082306, Length=476, Percent_Identity=23.109243697479, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56589; Mature: 56458

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNMSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASII
CCCCCCHHHHHHHHHEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAISNPVMGYITDNFYNTRLGRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYAL
HHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIYGKDSA
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
TPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRKHLGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGFARPFRIALQVVIVSVVAYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTV
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
YTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQPEIAV
HHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAE
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ELTGWKYEQCWGNNPLGVKESPTVIPKPVTES
HHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVNMSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASII
CCCCCHHHHHHHHHEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAISNPVMGYITDNFYNTRLGRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYAL
HHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIYGKDSA
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
TPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRKHLGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGFARPFRIALQVVIVSVVAYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTV
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
YTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQPEIAV
HHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAE
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ELTGWKYEQCWGNNPLGVKESPTVIPKPVTES
HHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Glucuronides [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Glucuronides [Periplasm] = Proton [Cytoplasm] + Glucuronides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]