Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 22126619

GI number: 22126619

Start: 3024987

End: 3025397

Strand: Direct

Name: fabF [H]

Synonym: y2741

Alternate gene names: 22126619

Gene position: 3024987-3025397 (Clockwise)

Preceding gene: 161484777

Following gene: 22126620

Centisome position: 65.75

GC content: 49.15

Gene sequence:

>411_bases
TTGTCTCCTGTTCAATCGAGTTTAAAAGGAAAAAGAATGAGTACACGCCATGTAGTAATTACAGGTATGGGTGTCGTTTC
CCCATTAGGCTGCGGTATCGAAACGGTCTGGCAACGGCTCTTGGCAGGGCAATCAGGCATCCGTGTTCTATCGGATGAAA
TTGTCGGTGACTTGCCCGCTAAAATTGGTGGGCAAGTGCCTACGTTAGCAGAAGACGCTAAAGCTGGTTTCGATCCAGAT
AAAGCGGTTACCCCAAAAGATCAAAAGAAAATGGATCGCTTTATTGAGTTTGCGATGGCGGCGGCCGATGAGGCAATTAG
CCAGGCAGGCTGGCATGCTGTAACGAACGGTGCAATAGTGATCCACACCCAACGCCTGAAATCAGATCCAGGGGGTAATC
TGCTCTCCTGA

Upstream 100 bases:

>100_bases
GCCCGGTCAAGCGAGATATAATGAATGAACGGCTGACATTCATGCATAAAAACGGTCAGTAAAGATTAAATAACCGTCTT
ATGGAGAACGGCCTTCTGGG

Downstream 100 bases:

>100_bases
TTCAGGAGAGTTTATGGTCACTTTTGAGACAGTTATGGAAATTAAAATCCTGCACAAGCAGGGAATGAGTAGCCGGGCGA
TTGCCAGAGAACTGGGGATC

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSPVQSSLKGKRMSTRHVVITGMGVVSPLGCGIETVWQRLLAGQSGIRVLSDEIVGDLPAKIGGQVPTLAEDAKAGFDPD
KAVTPKDQKKMDRFIEFAMAAADEAISQAGWHAVTNGAIVIHTQRLKSDPGGNLLS

Sequences:

>Translated_136_residues
MSPVQSSLKGKRMSTRHVVITGMGVVSPLGCGIETVWQRLLAGQSGIRVLSDEIVGDLPAKIGGQVPTLAEDAKAGFDPD
KAVTPKDQKKMDRFIEFAMAAADEAISQAGWHAVTNGAIVIHTQRLKSDPGGNLLS
>Mature_135_residues
SPVQSSLKGKRMSTRHVVITGMGVVSPLGCGIETVWQRLLAGQSGIRVLSDEIVGDLPAKIGGQVPTLAEDAKAGFDPDK
AVTPKDQKKMDRFIEFAMAAADEAISQAGWHAVTNGAIVIHTQRLKSDPGGNLLS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI223972627, Length=97, Percent_Identity=38.1443298969072, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI8923559, Length=97, Percent_Identity=38.1443298969072, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787337, Length=98, Percent_Identity=36.734693877551, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 14349; Mature: 14218

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVQSSLKGKRMSTRHVVITGMGVVSPLGCGIETVWQRLLAGQSGIRVLSDEIVGDLPA
CCCHHHHHCCCCCCCCEEEEECCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCH
KIGGQVPTLAEDAKAGFDPDKAVTPKDQKKMDRFIEFAMAAADEAISQAGWHAVTNGAIV
HHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEE
IHTQRLKSDPGGNLLS
EEEHHHCCCCCCCCCC
>Mature Secondary Structure 
SPVQSSLKGKRMSTRHVVITGMGVVSPLGCGIETVWQRLLAGQSGIRVLSDEIVGDLPA
CCHHHHHCCCCCCCCEEEEECCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCH
KIGGQVPTLAEDAKAGFDPDKAVTPKDQKKMDRFIEFAMAAADEAISQAGWHAVTNGAIV
HHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEE
IHTQRLKSDPGGNLLS
EEEHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]