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The map label for this gene is caiD [H]

Identifier: 22126590

GI number: 22126590

Start: 2995526

End: 2996296

Strand: Reverse

Name: caiD [H]

Synonym: y2711

Alternate gene names: 22126590

Gene position: 2996296-2995526 (Counterclockwise)

Preceding gene: 22126591

Following gene: 22126589

Centisome position: 65.13

GC content: 40.08

Gene sequence:

>771_bases
GTGGGCTCCTTATTCTTGAGCGTATCGATAACCACTTACGGCGTTATCGCTATGCATGAATATGTCACTGTACCTATCAA
ATTTAGCCCCGATTCATTAGCCGATTTCGAAAATCGCTTTATCTCTGCGCTAAATGACGAGCGCTATAAAGTCATTGTAC
TTATCGGAGGGCCTACCTACTTTAGTATGGGTATGGATCTTACGTATATTTCTACCCATTATGACGCCGACTTCGTGTCG
CAATTCTGCCATATTCTAAAAATGGTAAGGAACAGCCACAAGCCCGTATTAGCGAAGGTTGAAGGGAATGTTATCGCTGG
GGGGCTTGCCTTACTGTCGGTTGTCGATTTTATTCTGTCTAGCGATAGCGCGTCCTTTAGTTTGCCAGAAGTCACCTTTG
GAATTACACCAACAATAGCCATGTCTTGCTTACTTGAACGTATTAGGCCTCATCATCTTAAATACTTCGTATGGAGCTCA
AGTGTTATTTCGGCAAAACAAGCCCTAAAATGGGGTTTGATCGATCAGATAAATACACTGGAAAACTTAGATCAAGATAT
TCAAGTTATAAGTAATAAGCTATCTCGCATTCCAAAATCCGCTATAAGAGAAAGTAAATTACTGTTGGCTGAACAATATT
CTTTCGAAGAAAGTTTGGATTTAGGTAGCCATCTTCTGGTGGAGAGACTAAATGATGCTCAGACCATAGAAAAGATACGT
CACTACTTAGAAGACATTAAGTTATTTAATGATGAATATGCGGATGACTAA

Upstream 100 bases:

>100_bases
GAGCAACTGGAAAATGCACGTAGCGCACAAATGCAAGGTAAAGACTATCGTTTAGACGGGGACAACTTACAGGACTGGTA
TACACACCATTACAGCGGGA

Downstream 100 bases:

>100_bases
TATGAAAAAAATTTATTTAAGAAAAAGTGATGAAGGTATTGCTTTTATGCATATTAACGATCCAGTCAACAAAAATGCCA
TTGATGATGAGTTTTGTTTA

Product: enoyl-coa hydratase protein

Products: L-Carnitine.; L-carnitinyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA hydratase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGSLFLSVSITTYGVIAMHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVS
QFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSS
SVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIR
HYLEDIKLFNDEYADD

Sequences:

>Translated_256_residues
MGSLFLSVSITTYGVIAMHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVS
QFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSS
SVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIR
HYLEDIKLFNDEYADD
>Mature_255_residues
GSLFLSVSITTYGVIAMHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQ
FCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSS
VISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRH
YLEDIKLFNDEYADD

Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI221142681, Length=159, Percent_Identity=30.8176100628931, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022852
- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 28831; Mature: 28700

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLFLSVSITTYGVIAMHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTY
CCCEEEEEEHHHHHHEEEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
FSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILS
EECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEHHHHHHHHHHHHHC
SDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTL
CCCCCCCCCCEEECCCHHHHHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHH
ENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCHHHHHHHHH
HYLEDIKLFNDEYADD
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GSLFLSVSITTYGVIAMHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTY
CCEEEEEEHHHHHHEEEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
FSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILS
EECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEHHHHHHHHHHHHHC
SDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTL
CCCCCCCCCCEEECCCHHHHHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHH
ENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCHHHHHHHHH
HYLEDIKLFNDEYADD
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Carnitine; D-carnitinyl-CoA [C]

Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA