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The map label for this gene is wrbA [H]

Identifier: 22126332

GI number: 22126332

Start: 2711781

End: 2712395

Strand: Direct

Name: wrbA [H]

Synonym: y2449

Alternate gene names: 22126332

Gene position: 2711781-2712395 (Clockwise)

Preceding gene: 22126330

Following gene: 22126338

Centisome position: 58.94

GC content: 51.87

Gene sequence:

>615_bases
TTGGAGCACCGCGAGATGGCGAAAATTTTAGTACTCTATTATTCCATGTATGGGCATATCGAAACACTTGCTGGCGCGAT
TGCCGAAGGTGCCAGAAAAGTCAGTGGCGTTGACGTCACCATAAAACGAGTACCTGAAACCATGCCAGCCGAAGCTTTCG
CTAAAGCAGGTGGAAAAACAAACCAACAAGCGCCAGTCGCTACACCACACGAACTGGCCGATTATGATGGCATTATTTTC
GGTACACCGACTCGCTTTGGCAACATGTCCGGGCAGATGCGGACCTTCCTCGACCAGACTGGTGGGTTATGGGCATCGGG
TGCACTGTATGGCAAAGTGGCCAGCGTATTCGCCTCCACCGGGACAGGCGGAGGACAAGAACACACCATCACTTCAACCT
GGACCACTCTGGCCCATCACGGTTTTATCATTGTTCCAATCGGTTATGGTGCCAAAGAGTTATTTGATGTCTCGCAGACT
CGTGGTGGTACACCTTATGGCGCAACGACAATTGCCGGAGGTGACGGTTCCCGTCAGCCAAGCGCTGAAGAATTGGCGAT
AGCCCGTTTCCAAGGTGAACATGTAGCGAAAATTACGGCCAAGCTGAAGGGTTGA

Upstream 100 bases:

>100_bases
GTGGATTAAAAGTTGCAGCCTGTGCTGATTAGCTTATGGTTAATAGGTGTCATTAGCCGCGACGACTAATGACATCATCA
GCCTTATTCAATAAATTTGA

Downstream 100 bases:

>100_bases
TCATAAAGAAATGACAATGAACACGACGCCATAAAAGAATGTAGACGTCATAAAAAGCACCGCGCGATGATGGCGGTGCT
GTATTTTAAGCTTCGAGCAG

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: Trp repressor-binding protein [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MEHREMAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIF
GTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQT
RGGTPYGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG

Sequences:

>Translated_204_residues
MEHREMAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIF
GTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQT
RGGTPYGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG
>Mature_204_residues
MEHREMAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIF
GTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQT
RGGTPYGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG

Specific function: Seems to enhance the formation and/or stability of noncovalent complexes between the trp repressor protein and operator-bearing DNA [H]

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=199, Percent_Identity=82.4120603015075, Blast_Score=338, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=46.2311557788945, Blast_Score=176, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319849, Length=201, Percent_Identity=45.771144278607, Blast_Score=170, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319526, Length=202, Percent_Identity=37.6237623762376, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 21491; Mature: 21491

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHREMAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCCCC
NQQAPVATPHELADYDGIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFAST
CCCCCCCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHC
GTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPYGATTIAGGDGSRQP
CCCCCCCCEEHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
SAEELAIARFQGEHVAKITAKLKG
CHHHHHHHHHCCCCEEEEEEECCC
>Mature Secondary Structure
MEHREMAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCCCC
NQQAPVATPHELADYDGIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFAST
CCCCCCCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHC
GTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPYGATTIAGGDGSRQP
CCCCCCCCEEHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
SAEELAIARFQGEHVAKITAKLKG
CHHHHHHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA