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The map label for this gene is resA [H]

Identifier: 22126247

GI number: 22126247

Start: 2606790

End: 2607320

Strand: Reverse

Name: resA [H]

Synonym: y2363

Alternate gene names: 22126247

Gene position: 2607320-2606790 (Counterclockwise)

Preceding gene: 22126248

Following gene: 22126246

Centisome position: 56.67

GC content: 46.89

Gene sequence:

>531_bases
ATGGTAAATATCTTGATGAAAAGAGCCGCCATCATGTGGCGTAACTTGAAGATCATTGGATTGTGCAGTTTATTATTGCT
GCTCAGCGCCTGTAAGCAGGAAAAAGTCGCCCTTGGTGAAGTGGCACCTACGCTGGCCGCTTACGACTTACAAGGGGAGG
CCGTCGCGCTTGAGCAATGGGAAGGCAAGCTGGTCTATCTCAACTTTTGGTCAGTAAATTGTGGCGGGTGTTTAGCTGAA
ATGGCGACATTGAATCAATTGAGTCAGGAATATCAGGATCAGGCAGTGGTGGTCGCCATTAACACTGATCCTGAGCAAGT
GGAGATTGCCCCGGTATTGGCGCAGCACAATATTAATTACCCGGTCATCCGTGATCAATTGGGTATTACACAAGAACGTT
ATCAGGTTATAGGCACCCCAACATCGTTTTTGATTGACCGCAATGGCAAGGTCATTGAATGGCATCAGGGTGTGCGTAAT
GAGCAGGAACTGACCGCTTTATTTAAACAGAAGGTGTCAGAGAAACAATGA

Upstream 100 bases:

>100_bases
GAATTGCTAAACCATATCCATCGTCAAGGCCGTACTATTGTCATGGTGACCCATAATCCAGATTTAAGCTGTGTTGCTGA
CCGGGTTATCCGGCTGCAAC

Downstream 100 bases:

>100_bases
TGAAAATATTGCTGTTAGTGGCGAGTATGGGAGTGTTCAGCGTAGCCGTACAAGCTGCTGACGGTGAACATATCTATAAG
CAAACATGCTCAAGTTGTCA

Product: thioredoxin-family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MVNILMKRAAIMWRNLKIIGLCSLLLLLSACKQEKVALGEVAPTLAAYDLQGEAVALEQWEGKLVYLNFWSVNCGGCLAE
MATLNQLSQEYQDQAVVVAINTDPEQVEIAPVLAQHNINYPVIRDQLGITQERYQVIGTPTSFLIDRNGKVIEWHQGVRN
EQELTALFKQKVSEKQ

Sequences:

>Translated_176_residues
MVNILMKRAAIMWRNLKIIGLCSLLLLLSACKQEKVALGEVAPTLAAYDLQGEAVALEQWEGKLVYLNFWSVNCGGCLAE
MATLNQLSQEYQDQAVVVAINTDPEQVEIAPVLAQHNINYPVIRDQLGITQERYQVIGTPTSFLIDRNGKVIEWHQGVRN
EQELTALFKQKVSEKQ
>Mature_176_residues
MVNILMKRAAIMWRNLKIIGLCSLLLLLSACKQEKVALGEVAPTLAAYDLQGEAVALEQWEGKLVYLNFWSVNCGGCLAE
MATLNQLSQEYQDQAVVVAINTDPEQVEIAPVLAQHNINYPVIRDQLGITQERYQVIGTPTSFLIDRNGKVIEWHQGVRN
EQELTALFKQKVSEKQ

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19754; Mature: 19754

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNILMKRAAIMWRNLKIIGLCSLLLLLSACKQEKVALGEVAPTLAAYDLQGEAVALEQW
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCEEEEECC
EGKLVYLNFWSVNCGGCLAEMATLNQLSQEYQDQAVVVAINTDPEQVEIAPVLAQHNINY
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEHHHCCCCC
PVIRDQLGITQERYQVIGTPTSFLIDRNGKVIEWHQGVRNEQELTALFKQKVSEKQ
CEEHHHHCCCHHHHEEECCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNILMKRAAIMWRNLKIIGLCSLLLLLSACKQEKVALGEVAPTLAAYDLQGEAVALEQW
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCEEEEECC
EGKLVYLNFWSVNCGGCLAEMATLNQLSQEYQDQAVVVAINTDPEQVEIAPVLAQHNINY
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEHHHCCCCC
PVIRDQLGITQERYQVIGTPTSFLIDRNGKVIEWHQGVRNEQELTALFKQKVSEKQ
CEEHHHHCCCHHHHEEECCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA