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The map label for this gene is mbtI [H]

Identifier: 22126221

GI number: 22126221

Start: 2570885

End: 2572855

Strand: Direct

Name: mbtI [H]

Synonym: y2336

Alternate gene names: 22126221

Gene position: 2570885-2572855 (Clockwise)

Preceding gene: 22126210

Following gene: 22126224

Centisome position: 55.88

GC content: 46.88

Gene sequence:

>1971_bases
ATGGTCTTCATTAAGTCCACGCCACTAGAACTGACCCGCAGAAAAAACAGACCACCATCCCTATACACCTACACCTACAC
CTACACACCTCAGGTTATACCTTCCTCATTATCATTTACCCAAGCTATAGAAACTGCCGAAATGGTGAGGCCTCAGCCAT
GGGATAAAAATCATTTATCCCGTTGGCCGTTGTTACATGTAGCGCTCATATTGCCTGATATCCGCCGCTATCAACAACAA
TGTGGAACCCTGCCCAACCGACTCAAACACATCACGGGTTGGCCACTCCCCCCTTTTGGTAGGATAGATAGTCAACATTT
ATCTGCTCAGGCCCGAGAGCCTCTCCCAGAGGGAGTAACATCGCCCATGCCCTGCTCTGGAGAACCGCTTTACTATGCGC
AGTGTCAACAAACGATCTGTGCTCCCCCACTGACAATGGCGACAAAATTAGTCCAGCGTTATCAAGAGGGTGCCCGCAAT
ATCTCTCACAGTAAAAGCGGCTCAGAAGGATATTCGTCACTCACTGACAATGAAGAATGGCAACCCTACGCTATCTATGA
AAAAGACGGTGAGTTCTCGGTCGGTATTGGGCTGGCGGCACTGATAACTGCCTATCCTAATTATGTTCACATACGTTACC
AGCAGCAAAATGCTCATGGCGATAGCTTTAGCGGCGAACAATTTCAAGAGCGTGTTTGGTTATCCTCCGACATCGTCGGT
AATATTTCATCCGCACTGGCAAGTATCCCGATTAAAGAGTGGCGAGCTTATGGTCTCAGCCAATTGGAATTGGTTCATCT
CTTCCATAACCCGGCGTCTCACGCGGCCCCCGGTACCGCACTACTGCAAATTTTCCTTCCGCTGCATGAATATAGACTCA
ATCGCGGCAGCGCTATAATACGCAGTTTGCTTCCCTCTCACTTACCCCAACTGCTTACGATGCTGCAGCAATGTGACAGT
GACCAATATGACAACGCGCCCTCTATCAACAAGTCATCTATCTATAAATCATCTAGTTGTGAACCATCTATTTATGAGCC
ATCTATTTATGAACAACCTGGCGATGAATATGATGAAAATAATCAACGTGCCCATAAGCAAGACAGCCACCTGCAGACAC
AAGTAGAAAGAAGCGCCATCGAAATGCAGATACGCCAAACTGACCCTACTATTTTCTGTGATCGGGTAGCAAAAACCGTT
AATGAAATCAGGCAAGGTAAATATCAGAAAGCCATTTTATCGCGCCAGATACCGCTGCCAAATAATATTAATTTACTCGC
AAGCTACCAACGTGGGCGCATAAATAACACCTCGGCACGCTCCTATGCTTTCCGGATGCAAGGATTTGAATTAATGGGCT
TTAGCTCAAAGACTGCCGTGACTGTCTCAGCCAATGGCTGTCTGATCACCCAACTTTTAACCGATACACATGCACTGTCG
TCAGACCAAACTCAATCGGTGCCACTTCATCATGAATTACGAATTAATACTAAAGATATCACTGAACATACCAGCTCAAT
CCTCTCTGTTGTTGCAACGCTAACACCAATCTGTGTACCAGGCTCAGTTGCCATTGTTCCGTATATGAAGGTGCTTACTT
GCGGTAAGGTGCAAAATCTGGCCTCCTGTCTGCAAGGCCAGCTACAAAAAGGCATCAGCCACTGGCAAGCTATGCAATCC
CTGTATCCTGTAGCTGCCGATATTCCTAAAGATCATCTGATGCAAGCAACTCTTCATGAACTGGGATCATGGGAGGCCTA
TAGCAGCAGCGTGCTAATGGTTGACAGCAATGGTGCATTGGATGCGACGCTAATTTCAGAGAGCCTTTCCCGTAAGAATA
AAAGATTTGGATTACGAGCCGGAACCGAAATCACCCATCAAGCAGACCCCCTACTCAAGCTAGAAGAGACTCATGAGACG
CTGATCGCGATTGCCCGTTATCTGGTGTTGCAAACAGCAATGACCGATTAA

Upstream 100 bases:

>100_bases
ACTAACTGGATTAACATAATAATAGTGATGATAGAAATTATCATTAAAATAAATAGAAAAAAATAATTAATCAAAATAAC
TATTACATAAGGATGATGTC

Downstream 100 bases:

>100_bases
CCCCGCTGCCGCCCATTACTACAAAACCAAACCATTATAAAACAAGAGGTCCATATTCGGTTGATGCTCACAATGCCACT
TTGTGAACATAAGGTTAACT

Product: hypothetical protein

Products: NA

Alternate protein names: Mycobactin synthase protein I; Salicylate synthase mbtI [H]

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MVFIKSTPLELTRRKNRPPSLYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQQQ
CGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARN
ISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQCDS
DQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTV
NEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHALS
SDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQLQKGISHWQAMQS
LYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHET
LIAIARYLVLQTAMTD

Sequences:

>Translated_656_residues
MVFIKSTPLELTRRKNRPPSLYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQQQ
CGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARN
ISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQCDS
DQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTV
NEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHALS
SDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQLQKGISHWQAMQS
LYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHET
LIAIARYLVLQTAMTD
>Mature_656_residues
MVFIKSTPLELTRRKNRPPSLYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQQQ
CGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARN
ISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQCDS
DQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTV
NEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHALS
SDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQLQKGISHWQAMQS
LYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHET
LIAIARYLVLQTAMTD

Specific function: Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicyl

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family. Salicylate synthase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890
- InterPro:   IPR019996 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 73442; Mature: 73442

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFIKSTPLELTRRKNRPPSLYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLS
CEEEECCCHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
RWPLLHVALILPDIRRYQQQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVT
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
SPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARNISHSKSGSEGYSSLTDNEEW
CCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
CCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAII
HHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
RSLLPSHLPQLLTMLQQCDSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDEN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
NQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTVNEIRQGKYQKAILSRQIPLP
CCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHALS
CCCCEEEECCCCCCCCCCHHHEEHEECCEEEECCCCCEEEEEECCCEEHHHHHHHHHHCC
SDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNL
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ASCLQGQLQKGISHWQAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGAL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
DATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHETLIAIARYLVLQTAMTD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFIKSTPLELTRRKNRPPSLYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLS
CEEEECCCHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
RWPLLHVALILPDIRRYQQQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVT
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
SPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARNISHSKSGSEGYSSLTDNEEW
CCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDIVG
CCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
NISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAII
HHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
RSLLPSHLPQLLTMLQQCDSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDEN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
NQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTVNEIRQGKYQKAILSRQIPLP
CCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHALS
CCCCEEEECCCCCCCCCCHHHEEHEECCEEEECCCCCEEEEEECCCEEHHHHHHHHHHCC
SDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNL
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ASCLQGQLQKGISHWQAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGAL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
DATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHETLIAIARYLVLQTAMTD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA