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The map label for this gene is mdtI [H]

Identifier: 22126127

GI number: 22126127

Start: 2469658

End: 2470005

Strand: Reverse

Name: mdtI [H]

Synonym: y2241

Alternate gene names: 22126127

Gene position: 2470005-2469658 (Counterclockwise)

Preceding gene: 22126128

Following gene: 22126125

Centisome position: 53.69

GC content: 47.7

Gene sequence:

>348_bases
TTGAGTCAGGTGAGCATCATGCAGCAGCTTGAGTTTTACCCTATAGCTTTCTTGATCTTGGCCGTTATGCTGGAAATCGT
CGCTAATATCTTGCTGAAAATGTCAGATGGCTTTCGCCGAAAATGGTTGGGGATATTGTCCCTGTTGTCAGTATTAGGCG
CATTCAGTGCATTGGCGCAAGCAGTGAAGGGGATTGAGCTGTCGGTAGCTTATGCCTTGTGGGGCGGTTTTGGTATTGCG
GCCACTGTTGCGGCGGGCTGGATTCTGTTTAATCAACGGTTGAACTACAAAGGTTGGATTGGTTTGATCTTACTGCTGGC
GGGCATGGTGATGATTAAGTTGTCATAG

Upstream 100 bases:

>100_bases
ACTCGGAAACCAAAACAACCGAACTGCCATCGCGGTAATCGACCCCCTTCGGTACAGGAATTAAAAACACAGACTACCGG
CCATCATAAGGGTGTTGCTG

Downstream 100 bases:

>100_bases
CGGGGCCAGAGGCAGTAAGCGGAGGGTAGCCTGGCGGCTACTCTCCTTTGTTTTTGTGGCTTAGTGACATTTATCGTTTA
GCAACATCTATCACTCAACT

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 114

Protein sequence:

>115_residues
MSQVSIMQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIA
ATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS

Sequences:

>Translated_115_residues
MSQVSIMQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIA
ATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
>Mature_114_residues
SQVSIMQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYALWGGFGIAA
TVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=74.3119266055046, Blast_Score=144, Evalue=1e-36,
Organism=Escherichia coli, GI1786755, Length=101, Percent_Identity=34.6534653465347, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12563; Mature: 12431

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVSIMQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AVKGIELSVAYALWGGFGIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQVSIMQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AVKGIELSVAYALWGGFGIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA