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The map label for this gene is rnd [H]

Identifier: 22126121

GI number: 22126121

Start: 2462022

End: 2463182

Strand: Reverse

Name: rnd [H]

Synonym: y2235

Alternate gene names: 22126121

Gene position: 2463182-2462022 (Counterclockwise)

Preceding gene: 22126122

Following gene: 22126117

Centisome position: 53.54

GC content: 47.72

Gene sequence:

>1161_bases
TTGAAAGATAACGGATATAACGACCAAGAGAATGACGTTTTGAATTATCAGTTGATCACGACCAATAACGCATTGCAACA
GGTCTGCGAACAAGCCCGGACACATGCTCACATCGCGTTGGATACAGAGTTTGTCAGAACGCGCACTTACTACCCTCAGT
TGGGTTTGATTCAACTGTATGATGGTGAACAACTCTCACTTATAGATCCATTACCTATCACGGAATGGCAGCCTTTTCGC
GCGTTACTGCAAGATCTGAATGTGGTGAAATATTTACACGCAGGCAGTGAAGATCTCGAAGTGTTTTTAAACGCTTTTGA
CCAGATGCCAACCCCGATGATTGATACTCAGGTATTAGCGGCATTTTCTGGCCGTAGCCTATCCTGCGGCTTTGCCATGC
TGGTGGCTGAGTTTGAAGGTGTTGAGTTAGATAAAAGTGAATCACGTACAGACTGGATTGCCCGGCCGTTGAGTGAAAAA
CAGTGCGATTATGCGGCGGCTGATGTGTTTTATCTTTTACCTCTGGCGGCTAAATTAGTCGAAGCCACTGAGGCGGCAGG
GCGGATGGACGCGGCGAAAGACGAATGTCTATTGCTGTGCCGCCGTCGGAGTGAGACGCTCGATCCTGAACTGGCTTACC
GTGAGATTACCAATGCCTGGCAACTCCGTGGCCATCAACTGGCATGTTTGCAGAAATTAGCCGAATGGCGTTTACGTCAG
GCACGGGAGCGGGATTTGGCGGTTAACTTTGTGGTTAGGGAAGAGCACCTGTGGCAAGTTGCCCGCTATCAACCAACATC
ACTCGGTGAGTTAGATTCTCTTGGCTTGAGTGGGCAGGAGATCCGCTATCACGGGCGAACATTGCTGGCACTGGTCGCCG
AAGGGAATGCCGTCCCTGAAGATCAGCTTCCTCCCCCGATTGCTAACTTGATTGACCAACCGGGGTACAAAAAAGTCTTT
AAAGATATTAAAGCCTTGATTCAATCGGTCAGTGAACGTAGCGGATTAAGCAGTGAATTACTGGCATCACGTCGCCAAAT
TAATCAGTTACTCAATTGGCACTGGAAGTTGAAGCTTTCAGATGCTCAACCTGAATTATTAACAGGCTGGCGTGGCGATT
TATTGTCTTCTGAATTGCTTGAAATCTTACAACACTATTAA

Upstream 100 bases:

>100_bases
ATCAACAACGCCGGTTATCACCGGCGTTGTTGTGTTTGTTATCGAACTATAGCCAATAGATTTTAAGAAACAGGAAGGCG
GTAGCTAATAGACCTGCCAC

Downstream 100 bases:

>100_bases
TCAGTTTTGATATTAATCAGCCTTCAGGGTGGGATATTAATTCCACGCTGAAACTTTTCAGTTTTAATTTATGAACACTC
TTTTTAATTTATAAACAATC

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKDNGYNDQENDVLNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPITEWQPFR
ALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEK
QCDYAAADVFYLLPLAAKLVEATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQ
ARERDLAVNFVVREEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQPGYKKVF
KDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGDLLSSELLEILQHY

Sequences:

>Translated_386_residues
MKDNGYNDQENDVLNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPITEWQPFR
ALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEK
QCDYAAADVFYLLPLAAKLVEATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQ
ARERDLAVNFVVREEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQPGYKKVF
KDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGDLLSSELLEILQHY
>Mature_386_residues
MKDNGYNDQENDVLNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPITEWQPFR
ALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLAAFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEK
QCDYAAADVFYLLPLAAKLVEATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQ
ARERDLAVNFVVREEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPEDQLPPPIANLIDQPGYKKVF
KDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLSDAQPELLTGWRGDLLSSELLEILQHY

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=373, Percent_Identity=67.5603217158177, Blast_Score=531, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 43935; Mature: 43935

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNGYNDQENDVLNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLY
CCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCEEEEECHHHHHHHCCCCCCCEEEEE
DGEQLSLIDPLPITEWQPFRALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLA
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH
AFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLLPLAAKLV
HHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHH
EATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQ
HHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARERDLAVNFVVREEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPE
HHHCCCEEEEEEEHHHHHHHHHCCCCCCCCHHHCCCCCCHHHCCCCEEEEEEECCCCCCC
DQLPPPIANLIDQPGYKKVFKDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLS
CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEC
DAQPELLTGWRGDLLSSELLEILQHY
CCCCHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDNGYNDQENDVLNYQLITTNNALQQVCEQARTHAHIALDTEFVRTRTYYPQLGLIQLY
CCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCEEEEECHHHHHHHCCCCCCCEEEEE
DGEQLSLIDPLPITEWQPFRALLQDLNVVKYLHAGSEDLEVFLNAFDQMPTPMIDTQVLA
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH
AFSGRSLSCGFAMLVAEFEGVELDKSESRTDWIARPLSEKQCDYAAADVFYLLPLAAKLV
HHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHH
EATEAAGRMDAAKDECLLLCRRRSETLDPELAYREITNAWQLRGHQLACLQKLAEWRLRQ
HHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARERDLAVNFVVREEHLWQVARYQPTSLGELDSLGLSGQEIRYHGRTLLALVAEGNAVPE
HHHCCCEEEEEEEHHHHHHHHHCCCCCCCCHHHCCCCCCHHHCCCCEEEEEEECCCCCCC
DQLPPPIANLIDQPGYKKVFKDIKALIQSVSERSGLSSELLASRRQINQLLNWHWKLKLS
CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEC
DAQPELLTGWRGDLLSSELLEILQHY
CCCCHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]