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The map label for this gene is ycgM [H]

Identifier: 22126115

GI number: 22126115

Start: 2457043

End: 2457735

Strand: Reverse

Name: ycgM [H]

Synonym: y2229

Alternate gene names: 22126115

Gene position: 2457735-2457043 (Counterclockwise)

Preceding gene: 22126116

Following gene: 22126114

Centisome position: 53.42

GC content: 46.9

Gene sequence:

>693_bases
GTGTGTCTATTAGGGTATAAATTCAAGAGAGGCAGTATGTATCAACATAGAGACTGGCAAGGGGCTTTGCTGGATTTCCC
CGTAAATAAAGTGGTTTGCGTCGGCAGTAACTATGCCGAACATATCAAAGAGATGGGGAGTACTGCCTCTGTGGAGCCTG
TACTGTTTATCAAACCTGAAACCGCATTATGCGATATCCGCCAACCGGTATCGATACCGAAAGATTTTGGCTCAGTGCAT
CATGAAATTGAATTAGCCGTGTTGATCGGAACGCCGTTAAAGCAAGCCAGCGAAGATAGAGTCGCACGGGCGATTGCCGG
TTACGGTGTGGCATTGGACTTAACGCTACGTGAGCTGCAGGCAGGTTTTAAAAAAGCGGGGCAACCATGGGAAAAAGCCA
AGGCGTTTGATGGTTCTTGCCCGATATCCGGTTTTATTCCCGTTGCTGAGTTTGGTGATGCACAGCAGGCAGATTTATCG
CTAACGATTAATGGGGAAATCCGTCAACAGGGAAATACCCGTGACATGATTACACCAATTATTCCGTTAATCAGTTACAT
GAGCCGTTTCTTTACCTTACGTGCTGGCGATATCGTGCTGACCGGTACGCCGCAAGGCGTAGGGCCGATGCAGTCAGGTG
ATATGCTTAAAATTATGCTCAATGGCAAAACAGTGAATACCCGCATAATATAA

Upstream 100 bases:

>100_bases
CATTGGAATCGCTCTTACTATTTCGCTATTAGCATTGGTATGATGGCCGATAGTATCGGTCAATAGTCTGTGTTTGCCAC
GGTTGTAAGACCGTTGCTCA

Downstream 100 bases:

>100_bases
AGAGAAACGTGCCGTCCGACTCTACTGTCGGGCGGCAAAACTTGCATCTGTAAGCTAAAGCGTCTATAACGGCCCGCTTA
TTTATTTACACCGGATACCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MCLLGYKFKRGSMYQHRDWQGALLDFPVNKVVCVGSNYAEHIKEMGSTASVEPVLFIKPETALCDIRQPVSIPKDFGSVH
HEIELAVLIGTPLKQASEDRVARAIAGYGVALDLTLRELQAGFKKAGQPWEKAKAFDGSCPISGFIPVAEFGDAQQADLS
LTINGEIRQQGNTRDMITPIIPLISYMSRFFTLRAGDIVLTGTPQGVGPMQSGDMLKIMLNGKTVNTRII

Sequences:

>Translated_230_residues
MCLLGYKFKRGSMYQHRDWQGALLDFPVNKVVCVGSNYAEHIKEMGSTASVEPVLFIKPETALCDIRQPVSIPKDFGSVH
HEIELAVLIGTPLKQASEDRVARAIAGYGVALDLTLRELQAGFKKAGQPWEKAKAFDGSCPISGFIPVAEFGDAQQADLS
LTINGEIRQQGNTRDMITPIIPLISYMSRFFTLRAGDIVLTGTPQGVGPMQSGDMLKIMLNGKTVNTRII
>Mature_230_residues
MCLLGYKFKRGSMYQHRDWQGALLDFPVNKVVCVGSNYAEHIKEMGSTASVEPVLFIKPETALCDIRQPVSIPKDFGSVH
HEIELAVLIGTPLKQASEDRVARAIAGYGVALDLTLRELQAGFKKAGQPWEKAKAFDGSCPISGFIPVAEFGDAQQADLS
LTINGEIRQQGNTRDMITPIIPLISYMSRFFTLRAGDIVLTGTPQGVGPMQSGDMLKIMLNGKTVNTRII

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=194, Percent_Identity=43.298969072165, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI215422413, Length=194, Percent_Identity=43.298969072165, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI66348062, Length=194, Percent_Identity=43.298969072165, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI156231349, Length=181, Percent_Identity=35.3591160220994, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI40786394, Length=181, Percent_Identity=34.2541436464088, Blast_Score=111, Evalue=4e-25,
Organism=Escherichia coli, GI1787428, Length=219, Percent_Identity=72.1461187214612, Blast_Score=345, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=42.2680412371134, Blast_Score=162, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=32.1428571428571, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28571789, Length=188, Percent_Identity=38.8297872340425, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28572127, Length=180, Percent_Identity=30, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24663695, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25140; Mature: 25140

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLLGYKFKRGSMYQHRDWQGALLDFPVNKVVCVGSNYAEHIKEMGSTASVEPVLFIKPE
CEEECEEECCCCCCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCCCCCCCEEEEECCC
TALCDIRQPVSIPKDFGSVHHEIELAVLIGTPLKQASEDRVARAIAGYGVALDLTLRELQ
CHHHCCCCCCCCCHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHH
AGFKKAGQPWEKAKAFDGSCPISGFIPVAEFGDAQQADLSLTINGEIRQQGNTRDMITPI
HHHHHCCCCHHHHHCCCCCCCCCCCEEHHHCCCCCCCEEEEEECCEEECCCCCCHHHHHH
IPLISYMSRFFTLRAGDIVLTGTPQGVGPMQSGDMLKIMLNGKTVNTRII
HHHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEC
>Mature Secondary Structure
MCLLGYKFKRGSMYQHRDWQGALLDFPVNKVVCVGSNYAEHIKEMGSTASVEPVLFIKPE
CEEECEEECCCCCCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCCCCCCCEEEEECCC
TALCDIRQPVSIPKDFGSVHHEIELAVLIGTPLKQASEDRVARAIAGYGVALDLTLRELQ
CHHHCCCCCCCCCHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHH
AGFKKAGQPWEKAKAFDGSCPISGFIPVAEFGDAQQADLSLTINGEIRQQGNTRDMITPI
HHHHHCCCCHHHHHCCCCCCCCCCCEEHHHCCCCCCCEEEEEECCEEECCCCCCHHHHHH
IPLISYMSRFFTLRAGDIVLTGTPQGVGPMQSGDMLKIMLNGKTVNTRII
HHHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]