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The map label for this gene is 22126058

Identifier: 22126058

GI number: 22126058

Start: 2398961

End: 2400082

Strand: Direct

Name: 22126058

Synonym: y2170

Alternate gene names: NA

Gene position: 2398961-2400082 (Clockwise)

Preceding gene: 22126057

Following gene: 22126060

Centisome position: 52.14

GC content: 50.98

Gene sequence:

>1122_bases
TTGATGAAATGGTATGATGGACTACGGCATCCGGGTGTATTGGCGGCATTGTCTGCTGCAATACTGTTTGGTGCCGGTAC
CCCTCTGGCAAAACAATTACTGAATACCGTTAGCCCCTGGTTATTGGCCGGTTTACTTTACCTTGGCTCGGGTATTGGCT
TAACACTCTACCGTTTGATCACTCGCCCGGCGGCGGTGAGCCTGCCCCGTAATGAATTATTGTGGTTTATTGGTGCCATC
CTCTCCGGGGGGATCATCGCACCCGTGCTGCTAATGGTCGGCCTCACGGGTATGCCCGCCTCTGGCGCATCACTGTTACT
CAATGCTGAAGGGGTATTCACCGCCCTTTTAGCCTGGTTTGCCTTCAAAGAGAATGTTGACCGTCGTATTGCTCTGGGGA
TGGTGATTATCATCGCTGGCGCAGTTGTGCTTAGCTGGCCAGAAGAAGTACTTAACTGGTGGCCAAAAGAGGCTCAATTT
GCCGGATTATGGCCGACGCTGGCCATTTTAGGTGCCTGCTTTGCCTGGGGAATTGATAACAATCTGACCCGTAAAGTCTC
GCTGAACGATGCAACCTGGATTGCCGCCGTCAAAGGGGGCGTTGCCGGAGTGGTTAATCTGGCGCTGGCCTTCGCCCTCG
GAGCAACATTGCCCCCTTTGGCAAATCTCGCTGGCGCATTGTTGGTTGGATTTTTGGCTTATGGTGTCAGTTTGGCGCTA
TTTGTCATTGGATTACGTCACCTCGGTACTGCCCGCACCGGTGCCTATTTTTCTATTGCTCCGTTCTTAGGCGCAGTGTT
GGCTGTCGCCTTAGGTGACACTGTCACCATTCCGTTGCTCATCGCGGGTCTTTTGATGGCGATAGGGATCGGGTTACATC
TTACGGAGCAGCATGAACATCAACATACCCATGATGAAATGATACATGAGCATGAACATATTCATGACGAACATCATCAA
CATCGCCATGACTTTCCGGTAGACGCGGGTACCGCGCATAAGCATCGTCATCAGCACCTACCGATGGCACACTCTCATTC
GCATTTTCCTGATTCACACCATCAGCATAAACATCCTCGACATAAGCATAATCAACATAAGTATCATCAACATAAGCACT
AG

Upstream 100 bases:

>100_bases
AATATCAGCCGGTTAATTTTTTCTTGTTCAGAAAGCATTTTCCGGCTTTTTCTATGGGCTAAAATTATCACTTCCCGCTA
TTTGTGGATCACGAGCTGAA

Downstream 100 bases:

>100_bases
CGGTGCAAACGTTAGCGGTATAAACACCAAACTCTCACCGTTCATCCAATTGGCTGAAGCGCTGAACAAGATAATCCAAT
ACGCTGCGTACCGAAGGTAG

Product: cobalt-nickel resistance (export) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MMKWYDGLRHPGVLAALSAAILFGAGTPLAKQLLNTVSPWLLAGLLYLGSGIGLTLYRLITRPAAVSLPRNELLWFIGAI
LSGGIIAPVLLMVGLTGMPASGASLLLNAEGVFTALLAWFAFKENVDRRIALGMVIIIAGAVVLSWPEEVLNWWPKEAQF
AGLWPTLAILGACFAWGIDNNLTRKVSLNDATWIAAVKGGVAGVVNLALAFALGATLPPLANLAGALLVGFLAYGVSLAL
FVIGLRHLGTARTGAYFSIAPFLGAVLAVALGDTVTIPLLIAGLLMAIGIGLHLTEQHEHQHTHDEMIHEHEHIHDEHHQ
HRHDFPVDAGTAHKHRHQHLPMAHSHSHFPDSHHQHKHPRHKHNQHKYHQHKH

Sequences:

>Translated_373_residues
MMKWYDGLRHPGVLAALSAAILFGAGTPLAKQLLNTVSPWLLAGLLYLGSGIGLTLYRLITRPAAVSLPRNELLWFIGAI
LSGGIIAPVLLMVGLTGMPASGASLLLNAEGVFTALLAWFAFKENVDRRIALGMVIIIAGAVVLSWPEEVLNWWPKEAQF
AGLWPTLAILGACFAWGIDNNLTRKVSLNDATWIAAVKGGVAGVVNLALAFALGATLPPLANLAGALLVGFLAYGVSLAL
FVIGLRHLGTARTGAYFSIAPFLGAVLAVALGDTVTIPLLIAGLLMAIGIGLHLTEQHEHQHTHDEMIHEHEHIHDEHHQ
HRHDFPVDAGTAHKHRHQHLPMAHSHSHFPDSHHQHKHPRHKHNQHKYHQHKH
>Mature_373_residues
MMKWYDGLRHPGVLAALSAAILFGAGTPLAKQLLNTVSPWLLAGLLYLGSGIGLTLYRLITRPAAVSLPRNELLWFIGAI
LSGGIIAPVLLMVGLTGMPASGASLLLNAEGVFTALLAWFAFKENVDRRIALGMVIIIAGAVVLSWPEEVLNWWPKEAQF
AGLWPTLAILGACFAWGIDNNLTRKVSLNDATWIAAVKGGVAGVVNLALAFALGATLPPLANLAGALLVGFLAYGVSLAL
FVIGLRHLGTARTGAYFSIAPFLGAVLAVALGDTVTIPLLIAGLLMAIGIGLHLTEQHEHQHTHDEMIHEHEHIHDEHHQ
HRHDFPVDAGTAHKHRHQHLPMAHSHSHFPDSHHQHKHPRHKHNQHKYHQHKH

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 40410; Mature: 40410

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKWYDGLRHPGVLAALSAAILFGAGTPLAKQLLNTVSPWLLAGLLYLGSGIGLTLYRLI
CCCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TRPAAVSLPRNELLWFIGAILSGGIIAPVLLMVGLTGMPASGASLLLNAEGVFTALLAWF
HCCHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHH
AFKENVDRRIALGMVIIIAGAVVLSWPEEVLNWWPKEAQFAGLWPTLAILGACFAWGIDN
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
NLTRKVSLNDATWIAAVKGGVAGVVNLALAFALGATLPPLANLAGALLVGFLAYGVSLAL
CCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FVIGLRHLGTARTGAYFSIAPFLGAVLAVALGDTVTIPLLIAGLLMAIGIGLHLTEQHEH
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECCHHHH
QHTHDEMIHEHEHIHDEHHQHRHDFPVDAGTAHKHRHQHLPMAHSHSHFPDSHHQHKHPR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
HKHNQHKYHQHKH
CCCCCHHHHCCCC
>Mature Secondary Structure
MMKWYDGLRHPGVLAALSAAILFGAGTPLAKQLLNTVSPWLLAGLLYLGSGIGLTLYRLI
CCCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TRPAAVSLPRNELLWFIGAILSGGIIAPVLLMVGLTGMPASGASLLLNAEGVFTALLAWF
HCCHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHH
AFKENVDRRIALGMVIIIAGAVVLSWPEEVLNWWPKEAQFAGLWPTLAILGACFAWGIDN
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
NLTRKVSLNDATWIAAVKGGVAGVVNLALAFALGATLPPLANLAGALLVGFLAYGVSLAL
CCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FVIGLRHLGTARTGAYFSIAPFLGAVLAVALGDTVTIPLLIAGLLMAIGIGLHLTEQHEH
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECCHHHH
QHTHDEMIHEHEHIHDEHHQHRHDFPVDAGTAHKHRHQHLPMAHSHSHFPDSHHQHKHPR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
HKHNQHKYHQHKH
CCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]