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The map label for this gene is msbA [H]

Identifier: 22125981

GI number: 22125981

Start: 2302603

End: 2302824

Strand: Direct

Name: msbA [H]

Synonym: y2091

Alternate gene names: 22125981

Gene position: 2302603-2302824 (Clockwise)

Preceding gene: 22125980

Following gene: 22125982

Centisome position: 50.05

GC content: 47.75

Gene sequence:

>222_bases
ATGGCCCGCATTATCGCCAATCGCACGGTTATTACGATTGCCCATCGCCTATCGACCGTTCGTCACTGCCACCGTATTGC
CGTGATAACACAAGGCCGAGTCACCGAACTTGCCAGCCATGACGAATTACTGCAATTAAACGGCAGTTACGCTCGGCTTT
GGCAACAACAAGTTCATTTTAACCAAAACAAGTCCACCTTAACTAAAACAAGCCCACTTTAA

Upstream 100 bases:

>100_bases
AACGCCTTTATTTTGGCGCTACGCGAATCCCCGGATCTTAATTTTTGATGAAGCGACCAGCGCACTGGATGATGAGTCTC
AGTCGGAGATTCAGAAAAAC

Downstream 100 bases:

>100_bases
CCACGGGGAAATAAAATAAATATTATGTCTGCGTTTATTCAGCACATAAAAAACCGCTGGACGCGTTGTTTTACCCCCGC
GCGTACCCGTGATGAATATG

Product: C-terminal fragment of inner membrane permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 72

Protein sequence:

>73_residues
MARIIANRTVITIAHRLSTVRHCHRIAVITQGRVTELASHDELLQLNGSYARLWQQQVHFNQNKSTLTKTSPL

Sequences:

>Translated_73_residues
MARIIANRTVITIAHRLSTVRHCHRIAVITQGRVTELASHDELLQLNGSYARLWQQQVHFNQNKSTLTKTSPL
>Mature_72_residues
ARIIANRTVITIAHRLSTVRHCHRIAVITQGRVTELASHDELLQLNGSYARLWQQQVHFNQNKSTLTKTSPL

Specific function: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Drosophila melanogaster, GI21357907, Length=59, Percent_Identity=50.8474576271186, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011917
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 8345; Mature: 8214

Theoretical pI: Translated: 11.81; Mature: 11.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIIANRTVITIAHRLSTVRHCHRIAVITQGRVTELASHDELLQLNGSYARLWQQQVHF
CCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCEEEECCHHHHHHHHHHHC
NQNKSTLTKTSPL
CCCCCCCCCCCCC
>Mature Secondary Structure 
ARIIANRTVITIAHRLSTVRHCHRIAVITQGRVTELASHDELLQLNGSYARLWQQQVHF
CCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCEEEECCHHHHHHHHHHHC
NQNKSTLTKTSPL
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA