BacMap

Definition	Yersinia pestis KIM 10 chromosome, complete genome.
Accession	NC_004088
Length	4,600,755

Click here to switch to the map view.

The map label for this gene is yciK [H]

Identifier: 22125946

GI number: 22125946

Start: 2264516

End: 2265364

Strand: Reverse

Name: yciK [H]

Synonym: y2056

Alternate gene names: 22125946

Gene position: 2265364-2264516 (Counterclockwise)

Preceding gene: 22125948

Following gene: 22125945

Centisome position: 49.24

GC content: 50.88

Gene sequence:

>849_bases
TTGCATTGGTTTCACTTAAATATAAGAATGAGAAAGATCACACGGTATGGACGGGAAGAGTTCACTCCGCCAGCAAGAGG
AATAATTATGCATTATCAACCTAAACATGACCTGCTCAATCAGCGCATTATTCTCGTGACTGGCGCAGGTGATGGTATTG
GTCGTGAAGCGGCCCTGACTTACGCTCGGTTTGGTGCTCGCCTGATATTAGTGGGCCGCACCGAAAGTAAATTGCTCGCG
GTAAAAAAGCAGATAGCTGATGCGGGCGGTTTGCCAGCGTTAGTGCTGTCACTGGATCTATTGCATGCCACCGCCGCGGA
TTGTCAGCAACTTGCTGACACCGTAAGTGCACAGGTCCCTAGGCTGGATGGCGTCTTACATAACGCCGGTTTATTGGGTG
AAGTTGCCCCCATGTCCGAGCAAAGCATCGCCGTCTGGCAAGACGTCATGCAAGTGAATGTCAATGCAACATTTATGCTA
ACTCAAGCATTACTGCCATTATTACTGAAATCCCCTAGCGCCTCTCTGGTGTTCACCAGTTCCAGCGTTGGCCGTCAGGG
ACGTGCAGGCTGGGGAGCTTATTCGGTCTCAAAATTTGCCACGGAAGGCATGATGCAAGTACTGGCCGAGGAGTATAAAC
AGAGCAACCTGCGGGTTAACTGCATCAATCCTGGAGGAACCCGAACACAAATGCGGGCGACCGCATTCCCCGATGAAGAT
GCGAGCAAGTTGAAAACGCCAGCAGATATTATGCCGTTGTACCTCTATTTGATGGGCGATGACAGCCGTAGAAAAACGGG
GATCAGCTTCGATGCACAGCCCGGCCGTAAACCTGGTCCAGCTGAATAA

Upstream 100 bases:

>100_bases
AAGAAATTAACTCCACAAATACCGCCTTTCTTCATGTGTTTTTAGAGAGATACCTGCATTCTAGCGAACCACTGAGCTGG
CGTCTCCCGTAAATGAAAAA

Downstream 100 bases:

>100_bases
AAGGAACGTAATCATTATGTCTGAAGATCGCCACCAGCAGCGCCAACAACGATTAAAAGAAAAGGTAGATTCACGGATTG
CTGCAGCACAGGAAGTTCGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MHWFHLNIRMRKITRYGREEFTPPARGIIMHYQPKHDLLNQRIILVTGAGDGIGREAALTYARFGARLILVGRTESKLLA
VKKQIADAGGLPALVLSLDLLHATAADCQQLADTVSAQVPRLDGVLHNAGLLGEVAPMSEQSIAVWQDVMQVNVNATFML
TQALLPLLLKSPSASLVFTSSSVGRQGRAGWGAYSVSKFATEGMMQVLAEEYKQSNLRVNCINPGGTRTQMRATAFPDED
ASKLKTPADIMPLYLYLMGDDSRRKTGISFDAQPGRKPGPAE

Sequences:

>Translated_282_residues
MHWFHLNIRMRKITRYGREEFTPPARGIIMHYQPKHDLLNQRIILVTGAGDGIGREAALTYARFGARLILVGRTESKLLA
VKKQIADAGGLPALVLSLDLLHATAADCQQLADTVSAQVPRLDGVLHNAGLLGEVAPMSEQSIAVWQDVMQVNVNATFML
TQALLPLLLKSPSASLVFTSSSVGRQGRAGWGAYSVSKFATEGMMQVLAEEYKQSNLRVNCINPGGTRTQMRATAFPDED
ASKLKTPADIMPLYLYLMGDDSRRKTGISFDAQPGRKPGPAE
>Mature_282_residues
MHWFHLNIRMRKITRYGREEFTPPARGIIMHYQPKHDLLNQRIILVTGAGDGIGREAALTYARFGARLILVGRTESKLLA
VKKQIADAGGLPALVLSLDLLHATAADCQQLADTVSAQVPRLDGVLHNAGLLGEVAPMSEQSIAVWQDVMQVNVNATFML
TQALLPLLLKSPSASLVFTSSSVGRQGRAGWGAYSVSKFATEGMMQVLAEEYKQSNLRVNCINPGGTRTQMRATAFPDED
ASKLKTPADIMPLYLYLMGDDSRRKTGISFDAQPGRKPGPAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=241, Percent_Identity=28.2157676348548, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=27.1255060728745, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI10190704, Length=189, Percent_Identity=26.4550264550265, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=28.4552845528455, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7657478, Length=217, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503817, Length=205, Percent_Identity=27.3170731707317, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40807363, Length=212, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI20149619, Length=214, Percent_Identity=27.1028037383178, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40548397, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010158, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010156, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI22758144, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32455239, Length=237, Percent_Identity=27.8481012658228, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=237, Percent_Identity=27.8481012658228, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=27.4131274131274, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=75.6, Blast_Score=373, Evalue=1e-105,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=26.0162601626016, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=192, Percent_Identity=30.7291666666667, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=29.5275590551181, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=30.8333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=237, Percent_Identity=27.0042194092827, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=197, Percent_Identity=27.4111675126904, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=23.2824427480916, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=212, Percent_Identity=23.5849056603774, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=204, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=216, Percent_Identity=31.0185185185185, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=197, Percent_Identity=32.48730964467, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=229, Percent_Identity=27.9475982532751, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=29.0155440414508, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=218, Percent_Identity=30.2752293577982, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=27.4900398406374, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=210, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=186, Percent_Identity=28.494623655914, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71997402, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=205, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=198, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560176, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=29.2079207920792, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=213, Percent_Identity=24.4131455399061, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=208, Percent_Identity=26.4423076923077, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=29.5, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=183, Percent_Identity=28.4153005464481, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=211, Percent_Identity=24.1706161137441, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=214, Percent_Identity=28.9719626168224, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI212646214, Length=212, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193210355, Length=225, Percent_Identity=28, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=184, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=244, Percent_Identity=25, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=212, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=27.8008298755187, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=30.8080808080808, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=230, Percent_Identity=29.1304347826087, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319635, Length=148, Percent_Identity=28.3783783783784, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=30.9236947791165, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=31.3492063492063, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI23397609, Length=203, Percent_Identity=34.9753694581281, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=28.2786885245902, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=32.3232323232323, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643142, Length=197, Percent_Identity=34.010152284264, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24640492, Length=183, Percent_Identity=30.0546448087432, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI18859837, Length=227, Percent_Identity=30.3964757709251, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=28.2352941176471, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364892, Length=184, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45553409, Length=211, Percent_Identity=28.9099526066351, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647948, Length=211, Percent_Identity=28.9099526066351, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647946, Length=198, Percent_Identity=29.2929292929293, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30759; Mature: 30759

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWFHLNIRMRKITRYGREEFTPPARGIIMHYQPKHDLLNQRIILVTGAGDGIGREAALT
CEEEEEEEEEHHHHHHCHHHCCCCCCCEEEEECCCHHHHCCEEEEEEECCCCCCHHHHHH
YARFGARLILVGRTESKLLAVKKQIADAGGLPALVLSLDLLHATAADCQQLADTVSAQVP
HHHCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLDGVLHNAGLLGEVAPMSEQSIAVWQDVMQVNVNATFMLTQALLPLLLKSPSASLVFTS
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEC
SSVGRQGRAGWGAYSVSKFATEGMMQVLAEEYKQSNLRVNCINPGGTRTQMRATAFPDED
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCC
ASKLKTPADIMPLYLYLMGDDSRRKTGISFDAQPGRKPGPAE
HHHHCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHWFHLNIRMRKITRYGREEFTPPARGIIMHYQPKHDLLNQRIILVTGAGDGIGREAALT
CEEEEEEEEEHHHHHHCHHHCCCCCCCEEEEECCCHHHHCCEEEEEEECCCCCCHHHHHH
YARFGARLILVGRTESKLLAVKKQIADAGGLPALVLSLDLLHATAADCQQLADTVSAQVP
HHHCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLDGVLHNAGLLGEVAPMSEQSIAVWQDVMQVNVNATFMLTQALLPLLLKSPSASLVFTS
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEC
SSVGRQGRAGWGAYSVSKFATEGMMQVLAEEYKQSNLRVNCINPGGTRTQMRATAFPDED
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCC
ASKLKTPADIMPLYLYLMGDDSRRKTGISFDAQPGRKPGPAE
HHHHCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]