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The map label for this gene is sodB [H]

Identifier: 22125843

GI number: 22125843

Start: 2153751

End: 2154371

Strand: Reverse

Name: sodB [H]

Synonym: y1951

Alternate gene names: 22125843

Gene position: 2154371-2153751 (Counterclockwise)

Preceding gene: 22125844

Following gene: 22125842

Centisome position: 46.83

GC content: 45.89

Gene sequence:

>621_bases
TTGAAGAGCAAACACCCTGAGCACCCCCGAAAGGAGAGAGCTATGTCTTTTGAATTACCTGCATTACCTTACGCGCAAAA
TGCGCTGGAACCCCACATCTCTGCCGAAACGCTGGAATACCATTATGGTAAGCACCACAACACCTATGTGATCAACCTCA
ATAATCTGATTAAAGATACTGAGTTTGCAGGCAAATCACTGGAAGAGATCGTGAAAACCGCCAATGGCGGTGTGTTTAAT
AATGCGGCCCAAGTTTGGAACCATACCTTCTACTGGCATTGCCTGTCGCCAAATGGAGGCGGTGAACCTACTGGAAAAAT
CGCCGAGGCCATTAATAAGTCTTTTGGCTCATTTGCTGAATTTAAAGCGCAATTTACTGATGCTGCCGTGAAAAACTTTG
GCGCTGGTTGGACGTGGCTCGTTAAAAAAGCGGATGGGACATTGGCGATTGTCAGTACTTCTAACGCAGGAACACCGCTG
ACAACAACAGATAAACCCCTGTTGACCGTCGATGTGTGGGAACATGCTTACTATATTGATTACCGTAATGCGCGACCAAA
ATATCTGGAGAATTTCTGGGCAGTAGTTAACTGGTCTTTCGCTGAGAAAAACCTAGACTGA

Upstream 100 bases:

>100_bases
CCTGGTAGAAATTGCTAAGATTAGTACTTACAACAAAAATATAAAAATACCGTTTTTAACCGCTCTTCACCCCACACCTC
TCAACAATGGTGGATAGGAT

Downstream 100 bases:

>100_bases
GAGTCGTGAAGAGTAAGCAGTAACCGTATACAAGCTACATCGATAACATAAATAAGGGCGGTTTAACCGCCCTTATTATT
ACCATTCACCAGCAACGGTT

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKSKHPEHPRKERAMSFELPALPYAQNALEPHISAETLEYHYGKHHNTYVINLNNLIKDTEFAGKSLEEIVKTANGGVFN
NAAQVWNHTFYWHCLSPNGGGEPTGKIAEAINKSFGSFAEFKAQFTDAAVKNFGAGWTWLVKKADGTLAIVSTSNAGTPL
TTTDKPLLTVDVWEHAYYIDYRNARPKYLENFWAVVNWSFAEKNLD

Sequences:

>Translated_206_residues
MKSKHPEHPRKERAMSFELPALPYAQNALEPHISAETLEYHYGKHHNTYVINLNNLIKDTEFAGKSLEEIVKTANGGVFN
NAAQVWNHTFYWHCLSPNGGGEPTGKIAEAINKSFGSFAEFKAQFTDAAVKNFGAGWTWLVKKADGTLAIVSTSNAGTPL
TTTDKPLLTVDVWEHAYYIDYRNARPKYLENFWAVVNWSFAEKNLD
>Mature_206_residues
MKSKHPEHPRKERAMSFELPALPYAQNALEPHISAETLEYHYGKHHNTYVINLNNLIKDTEFAGKSLEEIVKTANGGVFN
NAAQVWNHTFYWHCLSPNGGGEPTGKIAEAINKSFGSFAEFKAQFTDAAVKNFGAGWTWLVKKADGTLAIVSTSNAGTPL
TTTDKPLLTVDVWEHAYYIDYRNARPKYLENFWAVVNWSFAEKNLD

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=191, Percent_Identity=46.0732984293194, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI67782305, Length=191, Percent_Identity=46.0732984293194, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI67782309, Length=183, Percent_Identity=38.7978142076503, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1787946, Length=191, Percent_Identity=81.6753926701571, Blast_Score=334, Evalue=2e-93,
Organism=Escherichia coli, GI1790342, Length=201, Percent_Identity=42.7860696517413, Blast_Score=157, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17506561, Length=184, Percent_Identity=37.5, Blast_Score=126, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17569479, Length=183, Percent_Identity=36.6120218579235, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321796, Length=213, Percent_Identity=35.6807511737089, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI17136812, Length=185, Percent_Identity=40.5405405405405, Blast_Score=131, Evalue=4e-31,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 23179; Mature: 23179

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKHPEHPRKERAMSFELPALPYAQNALEPHISAETLEYHYGKHHNTYVINLNNLIKDT
CCCCCCCCCHHHHCEEECCCCCCCHHHHCCCCCCHHHHHHHCCCCCCEEEEECHHHHHHH
EFAGKSLEEIVKTANGGVFNNAAQVWNHTFYWHCLSPNGGGEPTGKIAEAINKSFGSFAE
HHCCHHHHHHHHHHCCCCCCCHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHH
FKAQFTDAAVKNFGAGWTWLVKKADGTLAIVSTSNAGTPLTTTDKPLLTVDVWEHAYYID
HHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEE
YRNARPKYLENFWAVVNWSFAEKNLD
ECCCCHHHHHHHHHHEEEEHHCCCCC
>Mature Secondary Structure
MKSKHPEHPRKERAMSFELPALPYAQNALEPHISAETLEYHYGKHHNTYVINLNNLIKDT
CCCCCCCCCHHHHCEEECCCCCCCHHHHCCCCCCHHHHHHHCCCCCCEEEEECHHHHHHH
EFAGKSLEEIVKTANGGVFNNAAQVWNHTFYWHCLSPNGGGEPTGKIAEAINKSFGSFAE
HHCCHHHHHHHHHHCCCCCCCHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHH
FKAQFTDAAVKNFGAGWTWLVKKADGTLAIVSTSNAGTPLTTTDKPLLTVDVWEHAYYID
HHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEE
YRNARPKYLENFWAVVNWSFAEKNLD
ECCCCHHHHHHHHHHEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]