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The map label for this gene is sufD [H]

Identifier: 22125829

GI number: 22125829

Start: 2135306

End: 2136631

Strand: Direct

Name: sufD [H]

Synonym: y1937

Alternate gene names: 22125829

Gene position: 2135306-2136631 (Clockwise)

Preceding gene: 161484816

Following gene: 22125830

Centisome position: 46.41

GC content: 49.77

Gene sequence:

>1326_bases
ATGGCTGGCTTACCGACCAACAGTAACGTTCTGGAAAGACAGCGGCTAGAACAGCAGCGACAAGAACAGCAGCGGATTGA
TGCATTAAAGCATTTCGGTCAGTTGTTTAAGCAGCGTCAGATCGAACCCTCTGCGGATGCCCGCGCCCATTGGCAGCAGG
TGCTGCAACTGGGGTTCCCCGGCAGTAAACATGAAGACTGGAAATACACGCCGCTGGAGCGTTTATTCGCGCATGAATTC
AGTTTTCCCCATGCGCCAGATGTGACAACAGCGCAGTGCGATGCATTGTCTCTGGTACCCAATGCACACCGTTTGGTTTT
CATTAATGGCCAGTTTTCGCCGACGTTAAGTGACCGTGAGTGTGGTCCTTATCAATTAACGCATGCGGCTGAAAATGTGC
CGTTCCCTACGGCCATACAATCAGAGGTGTTTTTGCACCTGACAGAAAGTTTGGCGCAGGAACGTTTGCATATTCGGTTA
CCTGTAGGTCAACACAGTGACAAGTCCTTATACCTTCTGCATATCAGCTCAGGTAACGACTCGGATATGGTGAATACCAG
CCACTCTCGCCATCATCTGGTGGTTGAGGCGAACGCACAGGCTGAAGTTATAGAGCATTTTGTCAGCCTCAATGAACAAC
CCCATTTTACCGGGGCGCGGCTGACAATCGCGGTGGGTGATAACGCTGAATTGAATCATTATAAGTTGGCGTTTGAAACG
CCGAAGAGTTATCACTTTGCCCATAACGATCTGGTCTTGGGGCGTGATGCACGGGCGCGGAGTCACAGTTTCTTGCTGGG
GGCGGGGCTAACGCGCCATAACACCAGCAGCCAGTTAAATGGTGAAGGTTCGTCATTATCGATGAATAGCCTGCTGCTGC
CGGTTGGGCGCGAGATTTGTGATACCCGAACTTATTTGGAACATAACAAAGGCCACTGCGAAAGCCGCCAGTTGCATAAA
GTCATGGTCCGTGAGCGGGGCAAAGCTATTTTTAACGGCATGATTAAAGTCGCTAAACATGCGCTAAAAACTGACGGGCA
GATGACCAACAACAATCTGCTGTTGAGCCATTTGGCTGAAGTCGATACCAAACCTCAGTTGGAAATTTATGCCGATGATG
TGAAATGCAGCCACGGTGCCACCGTTGGGCGTATTGATGCGGAGCAACTATTTTATCTGCAATCGCGCGGTATCAATCAG
GCTGATGCACAACAGATGATTATTTTTGCATTTGCTGCTGAAGTGACTGAAGCTATCCACAATGAAGCCATCCGTAAACA
GGTGTTAGCACGTATTGCTGAGCGTTTGGCGTGGGAGTCTGTATGA

Upstream 100 bases:

>100_bases
CTGGATTACGTTAAACCTGATTTCGTCCATGTGTTGTATCAGGGGCGGATCATTAAATCGGGTGATTTCACGTTAGTGAA
ACAGTTGGAGGAGCAAGGCT

Downstream 100 bases:

>100_bases
ATTTTCCTATTGAACGTGTAAGAGCTGATTTTCCACTGTTGAGCCGCCAGGTTAATGGGCAGCCGTTGGTTTATCTGGAC
AGCGCAGCCAGTGCGCAAAA

Product: cysteine desulfurase activator complex subunit SufD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MAGLPTNSNVLERQRLEQQRQEQQRIDALKHFGQLFKQRQIEPSADARAHWQQVLQLGFPGSKHEDWKYTPLERLFAHEF
SFPHAPDVTTAQCDALSLVPNAHRLVFINGQFSPTLSDRECGPYQLTHAAENVPFPTAIQSEVFLHLTESLAQERLHIRL
PVGQHSDKSLYLLHISSGNDSDMVNTSHSRHHLVVEANAQAEVIEHFVSLNEQPHFTGARLTIAVGDNAELNHYKLAFET
PKSYHFAHNDLVLGRDARARSHSFLLGAGLTRHNTSSQLNGEGSSLSMNSLLLPVGREICDTRTYLEHNKGHCESRQLHK
VMVRERGKAIFNGMIKVAKHALKTDGQMTNNNLLLSHLAEVDTKPQLEIYADDVKCSHGATVGRIDAEQLFYLQSRGINQ
ADAQQMIIFAFAAEVTEAIHNEAIRKQVLARIAERLAWESV

Sequences:

>Translated_441_residues
MAGLPTNSNVLERQRLEQQRQEQQRIDALKHFGQLFKQRQIEPSADARAHWQQVLQLGFPGSKHEDWKYTPLERLFAHEF
SFPHAPDVTTAQCDALSLVPNAHRLVFINGQFSPTLSDRECGPYQLTHAAENVPFPTAIQSEVFLHLTESLAQERLHIRL
PVGQHSDKSLYLLHISSGNDSDMVNTSHSRHHLVVEANAQAEVIEHFVSLNEQPHFTGARLTIAVGDNAELNHYKLAFET
PKSYHFAHNDLVLGRDARARSHSFLLGAGLTRHNTSSQLNGEGSSLSMNSLLLPVGREICDTRTYLEHNKGHCESRQLHK
VMVRERGKAIFNGMIKVAKHALKTDGQMTNNNLLLSHLAEVDTKPQLEIYADDVKCSHGATVGRIDAEQLFYLQSRGINQ
ADAQQMIIFAFAAEVTEAIHNEAIRKQVLARIAERLAWESV
>Mature_440_residues
AGLPTNSNVLERQRLEQQRQEQQRIDALKHFGQLFKQRQIEPSADARAHWQQVLQLGFPGSKHEDWKYTPLERLFAHEFS
FPHAPDVTTAQCDALSLVPNAHRLVFINGQFSPTLSDRECGPYQLTHAAENVPFPTAIQSEVFLHLTESLAQERLHIRLP
VGQHSDKSLYLLHISSGNDSDMVNTSHSRHHLVVEANAQAEVIEHFVSLNEQPHFTGARLTIAVGDNAELNHYKLAFETP
KSYHFAHNDLVLGRDARARSHSFLLGAGLTRHNTSSQLNGEGSSLSMNSLLLPVGREICDTRTYLEHNKGHCESRQLHKV
MVRERGKAIFNGMIKVAKHALKTDGQMTNNNLLLSHLAEVDTKPQLEIYADDVKCSHGATVGRIDAEQLFYLQSRGINQA
DAQQMIIFAFAAEVTEAIHNEAIRKQVLARIAERLAWESV

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI1787971, Length=437, Percent_Identity=58.1235697940503, Blast_Score=485, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000825
- InterPro:   IPR011542 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 49612; Mature: 49480

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLPTNSNVLERQRLEQQRQEQQRIDALKHFGQLFKQRQIEPSADARAHWQQVLQLGFP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
GSKHEDWKYTPLERLFAHEFSFPHAPDVTTAQCDALSLVPNAHRLVFINGQFSPTLSDRE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCC
CGPYQLTHAAENVPFPTAIQSEVFLHLTESLAQERLHIRLPVGQHSDKSLYLLHISSGND
CCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCCC
SDMVNTSHSRHHLVVEANAQAEVIEHFVSLNEQPHFTGARLTIAVGDNAELNHYKLAFET
CCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEEC
PKSYHFAHNDLVLGRDARARSHSFLLGAGLTRHNTSSQLNGEGSSLSMNSLLLPVGREIC
CCCEEEECCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEHHHEECHHHHHHH
DTRTYLEHNKGHCESRQLHKVMVRERGKAIFNGMIKVAKHALKTDGQMTNNNLLLSHLAE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VDTKPQLEIYADDVKCSHGATVGRIDAEQLFYLQSRGINQADAQQMIIFAFAAEVTEAIH
CCCCCCEEEEECCEECCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
NEAIRKQVLARIAERLAWESV
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLPTNSNVLERQRLEQQRQEQQRIDALKHFGQLFKQRQIEPSADARAHWQQVLQLGFP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
GSKHEDWKYTPLERLFAHEFSFPHAPDVTTAQCDALSLVPNAHRLVFINGQFSPTLSDRE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCC
CGPYQLTHAAENVPFPTAIQSEVFLHLTESLAQERLHIRLPVGQHSDKSLYLLHISSGND
CCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCCC
SDMVNTSHSRHHLVVEANAQAEVIEHFVSLNEQPHFTGARLTIAVGDNAELNHYKLAFET
CCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEEC
PKSYHFAHNDLVLGRDARARSHSFLLGAGLTRHNTSSQLNGEGSSLSMNSLLLPVGREIC
CCCEEEECCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEHHHEECHHHHHHH
DTRTYLEHNKGHCESRQLHKVMVRERGKAIFNGMIKVAKHALKTDGQMTNNNLLLSHLAE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VDTKPQLEIYADDVKCSHGATVGRIDAEQLFYLQSRGINQADAQQMIIFAFAAEVTEAIH
CCCCCCEEEEECCEECCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
NEAIRKQVLARIAERLAWESV
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]