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The map label for this gene is marC [H]

Identifier: 22125792

GI number: 22125792

Start: 2096512

End: 2097225

Strand: Reverse

Name: marC [H]

Synonym: y1899

Alternate gene names: 22125792

Gene position: 2097225-2096512 (Counterclockwise)

Preceding gene: 22125794

Following gene: 22125790

Centisome position: 45.58

GC content: 43.7

Gene sequence:

>714_bases
TTGATTGATGTTATTTGCGGAGTAGGATCCATGCTAAGTATTTTCGAATTATTTAAAGCCGTTGGCTTAGGATTAGTATT
GCTGCTGCCATTGGCAAATCCACTGACGACGGTGGCCTTATTGCTAGGGTTATCCGGTAATATGACCCGCGAGGAGCGTA
ATAATCAGTCGTTAATGGCGGCAATTTATGTCTTCTTTATCATGACTATCGCGTTTTATGCCGGTCAGATCGTCATGAGT
ACATTTGGTATCTCTATTCCCGGTCTGCGTATAGCTGGTGGCTTAATTGTCGCGTTTATTGGTTTTCGTATGCTCTTTCC
GCAACAATCGGCTGAAGATACTCAACTGGAGGCAAAATCCCAGGATTTAAAAAAACGTAAATCCATCAATATTGCCTTTG
TACCGCTGGCAATGCCGAGTACTGCGGGGCCAGGTACGATTGCAATGATCATCAGTTCCGCTGCAACAATGAAAGACCAG
ACAATGTTTGCACCATGGGTATTGGCCATCGCCCCCGTAATCACATTCTTATGCGTTTCGTTGATTTTGTGGGGATCTTT
ACTCAGCTCAGGAGCGATTATGCGCTGGGTTGGTAAAAGCGGTATTGAAGCAATTTCACGTTTGATGGGATTCTTGCTGG
TATGTATGGGTGTGCAATTTATTATTAATGGCGTCTTAGAGTTGATCTCAACTTATCAACCTGTCATGGCTTAA

Upstream 100 bases:

>100_bases
CAAAGTATCGCGTACAGTGGCGAGGTTCGTAATAATACTCTTCACACAAGTAAGTTAAGCTGGTGTATGAATTATTGCCT
GATATCGTTTTTTTTCGGGT

Downstream 100 bases:

>100_bases
ATATCAAGACTCAGTAAATATAATTTCAAAGTAAAATAAAAAAGTAACTTGCCGTAAAATTTAAAGTAAACGCTAGCCGA
TGCTACACCATCCATAGGCT

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MIDVICGVGSMLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTIAFYAGQIVMS
TFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQ
TMFAPWVLAIAPVITFLCVSLILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA

Sequences:

>Translated_237_residues
MIDVICGVGSMLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTIAFYAGQIVMS
TFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQ
TMFAPWVLAIAPVITFLCVSLILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA
>Mature_237_residues
MIDVICGVGSMLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMAAIYVFFIMTIAFYAGQIVMS
TFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKSQDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQ
TMFAPWVLAIAPVITFLCVSLILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=73.7556561085973, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI1787494, Length=198, Percent_Identity=31.3131313131313, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789842, Length=205, Percent_Identity=24.8780487804878, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 25404; Mature: 25404

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVICGVGSMLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMA
CCEEHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCHHHHH
AIYVFFIMTIAFYAGQIVMSTFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAIAPVITFLCVS
HHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDVICGVGSMLSIFELFKAVGLGLVLLLPLANPLTTVALLLGLSGNMTREERNNQSLMA
CCEEHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCHHHHH
AIYVFFIMTIAFYAGQIVMSTFGISIPGLRIAGGLIVAFIGFRMLFPQQSAEDTQLEAKS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QDLKKRKSINIAFVPLAMPSTAGPGTIAMIISSAATMKDQTMFAPWVLAIAPVITFLCVS
HHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILWGSLLSSGAIMRWVGKSGIEAISRLMGFLLVCMGVQFIINGVLELISTYQPVMA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA