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The map label for this gene is yfcB [H]

Identifier: 22125479

GI number: 22125479

Start: 1751198

End: 1752199

Strand: Direct

Name: yfcB [H]

Synonym: y1584

Alternate gene names: 22125479

Gene position: 1751198-1752199 (Clockwise)

Preceding gene: 22125477

Following gene: 22125480

Centisome position: 38.06

GC content: 48.0

Gene sequence:

>1002_bases
TTGTCACGAGCTTCATGGCAAACTAGGCATATAGATAATAAATTTACACATAAGCAGTTGGAGAATACCTTGGACAAGAT
TTTCGTCGATGAAGCAGTAAATGAGCTGCACACCATTCAGGATATGCTGCGTTGGACCGTGAGCCGTTTTAATGCAGCTA
ATATTTTCTATGGTCACGGTACGGATAATCCGTGGGACGAAGCGGTACAACTGGTTTTCCCCAGTCTTTTTCTGCCCCTT
GATATTCCAGAGGATATACGCAGCTCGCGCCTAACGTCCAGCGAGCGCCATCGCATCGTTGAGCGGGTTATTCGCCGGGT
TAACGAGCGTATCCCGGTCGCTTACCTAACCAATAAAGCGTGGTTCTGTGGCATGGAATATTATGTGGATGAGCGGGTAT
TAGTGCCACGTTCACCAATTGGTGAGTTGATCGAAAATCGCTTTGATGGGCTAATTCATCATCAGCCAAATCATATTCTG
GATATGTGTACCGGCAGTGGCTGTATTGCCATTGCTTGCGCCTATGCTTTCCCTGACGCAGAAGTTGATGCAGTGGACAT
CTCCAATGATGTGCTGGCGGTAACTGAACACAATATTCAGCAACACGGCATGGAGCATCAGGTCACGCCCATTCGTTCCG
ATCTGTTCCGCGATTTACCACCAATCAAATATGACCTGATTGTGACCAATCCGCCCTATGTTGATGCCGAAGATATGGCC
GATTTACCGCAAGAGTTCCGTTTTGAACCTGAACTGGGTTTGGCTGCGGGTAGCGATGGTCTGAAACTGGCTCGTCGTAT
TTTGGCCTGTGCCCCCGACTTTTTACAGGATGACGGCGTGCTGATTTGTGAAGTTGGCAACAGCATGGTGCATTTGATGG
ATCAGTATCCAGATGTCCCATTCACTTGGCTGGAATTTGAAAAGGGTGGCGACGGGGTCTTTATGCTGACTAAACAGCAA
CTGATTGACTGCGCTGCACATTTCAGCATGTACCGTGATTAA

Upstream 100 bases:

>100_bases
CCGCCTTCCGACAACTCGAATTATTTAGAATATAAGTTAAATAGGGGGGCAGGCTTTTTTTATTATTCGGTTATCATTCA
ACTGATGTATTGCTGCTGAT

Downstream 100 bases:

>100_bases
TTGATCACTTCTTATCAAGTCTGTCAGTACGGTTAATCTCTATCTGGCAGACCGCTTATGACTCAAAGGAGCCGTGATGG
CTGGGAACAGTATTGGGCAG

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSRASWQTRHIDNKFTHKQLENTLDKIFVDEAVNELHTIQDMLRWTVSRFNAANIFYGHGTDNPWDEAVQLVFPSLFLPL
DIPEDIRSSRLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCGMEYYVDERVLVPRSPIGELIENRFDGLIHHQPNHIL
DMCTGSGCIAIACAYAFPDAEVDAVDISNDVLAVTEHNIQQHGMEHQVTPIRSDLFRDLPPIKYDLIVTNPPYVDAEDMA
DLPQEFRFEPELGLAAGSDGLKLARRILACAPDFLQDDGVLICEVGNSMVHLMDQYPDVPFTWLEFEKGGDGVFMLTKQQ
LIDCAAHFSMYRD

Sequences:

>Translated_333_residues
MSRASWQTRHIDNKFTHKQLENTLDKIFVDEAVNELHTIQDMLRWTVSRFNAANIFYGHGTDNPWDEAVQLVFPSLFLPL
DIPEDIRSSRLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCGMEYYVDERVLVPRSPIGELIENRFDGLIHHQPNHIL
DMCTGSGCIAIACAYAFPDAEVDAVDISNDVLAVTEHNIQQHGMEHQVTPIRSDLFRDLPPIKYDLIVTNPPYVDAEDMA
DLPQEFRFEPELGLAAGSDGLKLARRILACAPDFLQDDGVLICEVGNSMVHLMDQYPDVPFTWLEFEKGGDGVFMLTKQQ
LIDCAAHFSMYRD
>Mature_332_residues
SRASWQTRHIDNKFTHKQLENTLDKIFVDEAVNELHTIQDMLRWTVSRFNAANIFYGHGTDNPWDEAVQLVFPSLFLPLD
IPEDIRSSRLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCGMEYYVDERVLVPRSPIGELIENRFDGLIHHQPNHILD
MCTGSGCIAIACAYAFPDAEVDAVDISNDVLAVTEHNIQQHGMEHQVTPIRSDLFRDLPPIKYDLIVTNPPYVDAEDMAD
LPQEFRFEPELGLAAGSDGLKLARRILACAPDFLQDDGVLICEVGNSMVHLMDQYPDVPFTWLEFEKGGDGVFMLTKQQL
IDCAAHFSMYRD

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=228, Percent_Identity=29.8245614035088, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI87082085, Length=310, Percent_Identity=82.258064516129, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1787463, Length=194, Percent_Identity=30.9278350515464, Blast_Score=91, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24582226, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 38090; Mature: 37958

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRASWQTRHIDNKFTHKQLENTLDKIFVDEAVNELHTIQDMLRWTVSRFNAANIFYGHG
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TDNPWDEAVQLVFPSLFLPLDIPEDIRSSRLTSSERHRIVERVIRRVNERIPVAYLTNKA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCC
WFCGMEYYVDERVLVPRSPIGELIENRFDGLIHHQPNHILDMCTGSGCIAIACAYAFPDA
EEECHHHHCCCEEECCCCCHHHHHHHHHCCCEECCCCHHHHHHCCCCCEEEEEEHHCCCC
EVDAVDISNDVLAVTEHNIQQHGMEHQVTPIRSDLFRDLPPIKYDLIVTNPPYVDAEDMA
CCEEEECCCCEEEEEHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
DLPQEFRFEPELGLAAGSDGLKLARRILACAPDFLQDDGVLICEVGNSMVHLMDQYPDVP
CCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCEEEEECCCHHHHHHHHCCCCC
FTWLEFEKGGDGVFMLTKQQLIDCAAHFSMYRD
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRASWQTRHIDNKFTHKQLENTLDKIFVDEAVNELHTIQDMLRWTVSRFNAANIFYGHG
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TDNPWDEAVQLVFPSLFLPLDIPEDIRSSRLTSSERHRIVERVIRRVNERIPVAYLTNKA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCC
WFCGMEYYVDERVLVPRSPIGELIENRFDGLIHHQPNHILDMCTGSGCIAIACAYAFPDA
EEECHHHHCCCEEECCCCCHHHHHHHHHCCCEECCCCHHHHHHCCCCCEEEEEEHHCCCC
EVDAVDISNDVLAVTEHNIQQHGMEHQVTPIRSDLFRDLPPIKYDLIVTNPPYVDAEDMA
CCEEEECCCCEEEEEHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
DLPQEFRFEPELGLAAGSDGLKLARRILACAPDFLQDDGVLICEVGNSMVHLMDQYPDVP
CCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCEEEEECCCHHHHHHHHCCCCC
FTWLEFEKGGDGVFMLTKQQLIDCAAHFSMYRD
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2182772; 2969724; 7984428 [H]