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The map label for this gene is fadL [H]

Identifier: 22125472

GI number: 22125472

Start: 1743089

End: 1744360

Strand: Reverse

Name: fadL [H]

Synonym: y1577

Alternate gene names: 22125472

Gene position: 1744360-1743089 (Counterclockwise)

Preceding gene: 22125478

Following gene: 22125460

Centisome position: 37.91

GC content: 48.58

Gene sequence:

>1272_bases
TTGGTCATGAACCAGAAAAACCTGTTTACCCGCTCAGCTCTGGCAGCAGCTATCGCTCTTATTTCATCGAACGTTTCTGC
AGCCGGTTTTCAGTTGAATGAATATTCAGCCGCCGCTCTAGGGCGTGCTTTCTCTGGTGAAGGCGCAGTGGCTGATAATG
CTTCCGTTGGTAGCCGCAATCCTGCAGCAATGACTTTATTCGACCGCCCTTCTTTCTCCGGTGGTGTGATTTATATTGAT
CCAAGTGTTGATATCACGGGGACGTCGCCAAGTGGCAAAAGTACGGATGCCAGTAACATTGCGCCATCAGCGTGGGTTCC
GAATCTCCACTTTATTATGCCATTGGATGAACAGTGGGCAATCGGTGCTTCTGCGACCTCTAACTACGGTTTAGCCACTG
AATTTAATGATGATTATGTGGCAGGCATGTTAGGCGGCCAAACCGATCTGAAAACGGCTAACCTCAACCTAAGTGCCGCG
TACCGCCTGAATGATAACTTCAGTTTTGGCCTGGGGTTTGATGCAGTCTATGCTGATGCGAAAATTGTGCGCCATCTCGG
TGAAGCTGGCGGGGGTCTATTGCCTGCTAACACTGAAGCCGCCAGGTTGGAAGGTACCAAATGGGGTTACGGCTGGAATA
CGGGTATTTTGTATGAAATCGATAAAGAAAACCGCTACAGCTTCACTTATCGTTCTGAAGTCAATATCGATTTTGACGGT
GATTACAGTAACCAACTACCTGTTATTTTCGGTGGTCTGGGTGGAAAAACGGTCCCTGGTTCCCTAACTCTGAACCTGCC
CGCCGTGTGGGAAGTCTCCGGCTACAATAAAGTCGCGCCACAATGGGCCATTCACTACAGCATGGCTTACACCACCTGGA
GCAGTTTCAAGGAGTTAAAAGCAACCGCGTCTAATGGCGATGTGCTGTTTGATAAACATGAAGGCTTCAGAGATGCCTAC
CGTATTGCGTTAGGGACCACCTATTACTACGATGATAACTGGACATTCCGCACCGGTATTGCCTTTGATGATAGCCCGAT
CCCCGCAGGAAACCGTTCAATTTCCATCCCGGACCAAGATCGTTTCTGGCTCAGTGCAGGTACCACCTACGCCTTCAACA
AAAATGCCTCTGTTGATGTCGGTATTGCTTATATGAAAAGCCAGAATGTCAGTATTACCGAAAAGACCCCGGCCCCATCT
AACACCACATATGAGTTCAACTCGAAAGGTTCCGCGATGCTATACGGTGTGAACTTCAACTACACATTCTAA

Upstream 100 bases:

>100_bases
CTTCAGTCACTGGTCTGCTTTGTCTGACCGATAACAGACCCTACAATCCCGCACTTTCTTGTTACGGTATGTAACATAGT
TTAAATAAAACAATGAGGTT

Downstream 100 bases:

>100_bases
TAGCCAGTCATTCATCACCTTATCCAATAGAAAAGCGCCTGATGGCGCTTTTCTATTTTGAATACGGCGGTGAGTACTGC
GCTAGACCAGTTAATATCAA

Product: long-chain fatty acid outer membrane transporter

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MVMNQKNLFTRSALAAAIALISSNVSAAGFQLNEYSAAALGRAFSGEGAVADNASVGSRNPAAMTLFDRPSFSGGVIYID
PSVDITGTSPSGKSTDASNIAPSAWVPNLHFIMPLDEQWAIGASATSNYGLATEFNDDYVAGMLGGQTDLKTANLNLSAA
YRLNDNFSFGLGFDAVYADAKIVRHLGEAGGGLLPANTEAARLEGTKWGYGWNTGILYEIDKENRYSFTYRSEVNIDFDG
DYSNQLPVIFGGLGGKTVPGSLTLNLPAVWEVSGYNKVAPQWAIHYSMAYTTWSSFKELKATASNGDVLFDKHEGFRDAY
RIALGTTYYYDDNWTFRTGIAFDDSPIPAGNRSISIPDQDRFWLSAGTTYAFNKNASVDVGIAYMKSQNVSITEKTPAPS
NTTYEFNSKGSAMLYGVNFNYTF

Sequences:

>Translated_423_residues
MVMNQKNLFTRSALAAAIALISSNVSAAGFQLNEYSAAALGRAFSGEGAVADNASVGSRNPAAMTLFDRPSFSGGVIYID
PSVDITGTSPSGKSTDASNIAPSAWVPNLHFIMPLDEQWAIGASATSNYGLATEFNDDYVAGMLGGQTDLKTANLNLSAA
YRLNDNFSFGLGFDAVYADAKIVRHLGEAGGGLLPANTEAARLEGTKWGYGWNTGILYEIDKENRYSFTYRSEVNIDFDG
DYSNQLPVIFGGLGGKTVPGSLTLNLPAVWEVSGYNKVAPQWAIHYSMAYTTWSSFKELKATASNGDVLFDKHEGFRDAY
RIALGTTYYYDDNWTFRTGIAFDDSPIPAGNRSISIPDQDRFWLSAGTTYAFNKNASVDVGIAYMKSQNVSITEKTPAPS
NTTYEFNSKGSAMLYGVNFNYTF
>Mature_423_residues
MVMNQKNLFTRSALAAAIALISSNVSAAGFQLNEYSAAALGRAFSGEGAVADNASVGSRNPAAMTLFDRPSFSGGVIYID
PSVDITGTSPSGKSTDASNIAPSAWVPNLHFIMPLDEQWAIGASATSNYGLATEFNDDYVAGMLGGQTDLKTANLNLSAA
YRLNDNFSFGLGFDAVYADAKIVRHLGEAGGGLLPANTEAARLEGTKWGYGWNTGILYEIDKENRYSFTYRSEVNIDFDG
DYSNQLPVIFGGLGGKTVPGSLTLNLPAVWEVSGYNKVAPQWAIHYSMAYTTWSSFKELKATASNGDVLFDKHEGFRDAY
RIALGTTYYYDDNWTFRTGIAFDDSPIPAGNRSISIPDQDRFWLSAGTTYAFNKNASVDVGIAYMKSQNVSITEKTPAPS
NTTYEFNSKGSAMLYGVNFNYTF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=453, Percent_Identity=63.355408388521, Blast_Score=569, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR001702
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 45699; Mature: 45699

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMNQKNLFTRSALAAAIALISSNVSAAGFQLNEYSAAALGRAFSGEGAVADNASVGSRN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCEECCCCCCCCCCCCCCCC
PAAMTLFDRPSFSGGVIYIDPSVDITGTSPSGKSTDASNIAPSAWVPNLHFIMPLDEQWA
CCEEEEEECCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEE
IGASATSNYGLATEFNDDYVAGMLGGQTDLKTANLNLSAAYRLNDNFSFGLGFDAVYADA
ECCCCCCCCCEEEECCCCEEEEECCCCCCEEEECCEEEEEEEECCCEEEECCCHHHHHHH
KIVRHLGEAGGGLLPANTEAARLEGTKWGYGWNTGILYEIDKENRYSFTYRSEVNIDFDG
HHHHHHHHHCCCCCCCCCCHHEECCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEEEECC
DYSNQLPVIFGGLGGKTVPGSLTLNLPAVWEVSGYNKVAPQWAIHYSMAYTTWSSFKELK
CCCCCCCEEEECCCCCCCCCEEEEECCEEEEECCCCCCCCCEEEEEEEEEHHHHHHHHHH
ATASNGDVLFDKHEGFRDAYRIALGTTYYYDDNWTFRTGIAFDDSPIPAGNRSISIPDQD
HCCCCCCEEEECCCCCCCEEEEEEEEEEEECCCEEEEEEEEECCCCCCCCCCEEECCCCC
RFWLSAGTTYAFNKNASVDVGIAYMKSQNVSITEKTPAPSNTTYEFNSKGSAMLYGVNFN
CEEEECCCEEEECCCCCEEEEEEEEECCCCEEEECCCCCCCCEEEECCCCCEEEEEEEEE
YTF
EEC
>Mature Secondary Structure
MVMNQKNLFTRSALAAAIALISSNVSAAGFQLNEYSAAALGRAFSGEGAVADNASVGSRN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCEECCCCCCCCCCCCCCCC
PAAMTLFDRPSFSGGVIYIDPSVDITGTSPSGKSTDASNIAPSAWVPNLHFIMPLDEQWA
CCEEEEEECCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEE
IGASATSNYGLATEFNDDYVAGMLGGQTDLKTANLNLSAAYRLNDNFSFGLGFDAVYADA
ECCCCCCCCCEEEECCCCEEEEECCCCCCEEEECCEEEEEEEECCCEEEECCCHHHHHHH
KIVRHLGEAGGGLLPANTEAARLEGTKWGYGWNTGILYEIDKENRYSFTYRSEVNIDFDG
HHHHHHHHHCCCCCCCCCCHHEECCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEEEECC
DYSNQLPVIFGGLGGKTVPGSLTLNLPAVWEVSGYNKVAPQWAIHYSMAYTTWSSFKELK
CCCCCCCEEEECCCCCCCCCEEEEECCEEEEECCCCCCCCCEEEEEEEEEHHHHHHHHHH
ATASNGDVLFDKHEGFRDAYRIALGTTYYYDDNWTFRTGIAFDDSPIPAGNRSISIPDQD
HCCCCCCEEEECCCCCCCEEEEEEEEEEEECCCEEEEEEEEECCCCCCCCCCEEECCCCC
RFWLSAGTTYAFNKNASVDVGIAYMKSQNVSITEKTPAPSNTTYEFNSKGSAMLYGVNFN
CEEEECCCEEEECCCCCEEEEEEEEECCCCEEEECCCCCCCCEEEECCCCCEEEEEEEEE
YTF
EEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]