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The map label for this gene is glk [H]

Identifier: 22125402

GI number: 22125402

Start: 1668704

End: 1669678

Strand: Direct

Name: glk [H]

Synonym: y1505

Alternate gene names: 22125402

Gene position: 1668704-1669678 (Clockwise)

Preceding gene: 22125401

Following gene: 22125404

Centisome position: 36.27

GC content: 50.26

Gene sequence:

>975_bases
TTGATGACGACTTATGCCCTGGTGGGTGACGTTGGCGGTACGAATGCCCGGTTGGCGCTTTGCGCTGTTGCAACGGGCGA
GATATTGCAAGCAAAGACATATTCAGGGTTGGAATATGAAAGTTTAGAGGATGTAATCAAACAATATCTATCAGAGCATC
AAGCCAAGGTCACCGATGCTTGTATCGCGATTGCCTGCCCGATTACCGGGGATTGGGTCGCAATGACCAATCATACTTGG
GCATTTTCTATTGCCGCCATGCAACAGAATCTGGGTCTGGACCATTTGGAAGTGATCAATGACTTCACCGCAGTCTCCAT
GGCTATCCCCGTGTTACCTGCCCAAGATGTTCTGCAATTTGGTGGCACACAGCCACAGCCTGGCAAACCGGTGGCAGTGT
ATGGCGCAGGTACTGGGCTGGGGGTAGCACATTTAGTGAATGTTGATCGCCGTTGGATTAGTTTAGCGGGAGAGGGCGGG
CATGTTGATTTCGCGCCTAATAGTGAAGAAGAAGACCAGATTCTGGCCGTATTGCGCCAGGAGTTGGGGCATGTTTCCGC
TGAGCGGGTGCTATCTGGGCCGGGCTTAGTCAATTTATATCGGGCAATTGTGATTTCTGATGCGCGCCTACCAGAGAAAC
TGGCACCGAAAGATATTACCGCACGGGCGCTGGCGGATAGCTGTACCGATTGTCGCCGGGCATTATCACTATTTTGCGTA
ATTATGGGCCGCTTTGGGGGCAATTTAGCCCTTAACCTCAGTACGTTTGGTGGCGTTTATATTGCGGGGGGCATCGTGCC
GCGCTTTATGGAGTTCTTTAAAGCCTCTGGTTTTCGCGCTGCGTTTGAAGATAAAGGCCGTTTTAAAGATTTCTTACAAG
ATATTCCGGTGTATATGATTACTCATCCACAACCCGGTTTACTGGGGGCTGGTGCCTATTTACGCCAAAAATTGGGGTAT
GAGTTGTCAAGCTAA

Upstream 100 bases:

>100_bases
GTCACAAAACAAAGTGGTTTACTGTATTGAGATTGTTGTTTTTCTGGCGTGATTTTACAGTGGGCATAATTGACGTTAAG
CATCTTGCAATGGAGAGATT

Downstream 100 bases:

>100_bases
CCGAATTGTCTTTATCGTGGGCGCAGAAGAATATCTGCCGGGAGGATAAGTTCCGGCAGATATGATGCGGAAGAAGGCTA
GTCTGTTATGCCCAACTGCT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MMTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDACIAIACPITGDWVAMTNHTW
AFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGG
HVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCV
IMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQKLGY
ELSS

Sequences:

>Translated_324_residues
MMTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDACIAIACPITGDWVAMTNHTW
AFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGG
HVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCV
IMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQKLGY
ELSS
>Mature_324_residues
MMTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDACIAIACPITGDWVAMTNHTW
AFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGG
HVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCV
IMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQKLGY
ELSS

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=321, Percent_Identity=79.4392523364486, Blast_Score=541, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34795; Mature: 34795

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDA
CCEEEEEEECCCCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
CIAIACPITGDWVAMTNHTWAFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQF
EEEEECCCCCCEEEEECCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
GGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGGHVDFAPNSEEEDQILAVLRQ
CCCCCCCCCCEEEEECCCCCCHHHHHHHCHHEEEEECCCCEEECCCCCCCHHHHHHHHHH
ELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCV
HHCCCCHHHHHCCCCHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
IMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMI
HHHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHCCCEEEE
THPQPGLLGAGAYLRQKLGYELSS
ECCCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MMTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDA
CCEEEEEEECCCCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
CIAIACPITGDWVAMTNHTWAFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQF
EEEEECCCCCCEEEEECCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
GGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGGHVDFAPNSEEEDQILAVLRQ
CCCCCCCCCCEEEEECCCCCCHHHHHHHCHHEEEEECCCCEEECCCCCCCHHHHHHHHHH
ELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCV
HHCCCCHHHHHCCCCHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
IMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMI
HHHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHCCCEEEE
THPQPGLLGAGAYLRQKLGYELSS
ECCCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA