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The map label for this gene is gsiC [H]

Identifier: 22125133

GI number: 22125133

Start: 1381883

End: 1382866

Strand: Direct

Name: gsiC [H]

Synonym: y1232

Alternate gene names: 22125133

Gene position: 1381883-1382866 (Clockwise)

Preceding gene: 22125132

Following gene: 22125134

Centisome position: 30.04

GC content: 51.22

Gene sequence:

>984_bases
ATGGACCTGTCAGTGATGAAGGGGATCTCGCTGTTTACTCTGCGCTTAATTTGCCTGCTGCTGGTCACCGCAGCCGGTAC
TTTTACATTGCTGAGTTTTTCCCCTGTTGACCCTATACGTGCCTATATTGGTAGCGATTTACTGCATGTGCCGCCAGAGC
AATACCCACTGATTGCGGCTCGTTGGGGGCTGGATTTACCTTTGTGGCAACGTTTTTTGCATTGGTTTACTCAAGTGCTC
CAAGGGGATTTTGGTTACTCGATGCTGTATAACGCGCCGGTTTCTCAGGTGATAGGTGAGCGTTTTGCTACCTCGTTTGC
GTTATTGGTATCGGCCTGGCTATTTTCGGGAATTGTCGGGTTGCTATTGGGGTTGACCGCTGGGCGCTATCTCAACCGTT
GGCCTGATCGTCTGATTTCAACGTTGTCCTATTTATTGGCATCGTTGCCCACCTTTTGGATCGGTCTATTGTTGTTGTCG
TTATTTGCGGTGAAGCTCAATTGGGCCCCCATTTGCTGTGCATGGACGCCAGGGAGTCAGGCCGAGACCGCCAGTTGGGG
GGATAAGCTTCACCACCTGATTTTACCGATGCTAGCGCTGGGGTTACTGGGGGTTGGGAACATTGCACTGCATACCCGTG
CCAGAGTTGCTGAAGTGATGAATAGCGAATTTATTCGCTATGCACAGGCGCAGGGGGATAAAGGCTGGCCTTTGGTGAAC
TTCCATATTTTACGCCATGCCATTACACCCGCGCTTTGCCTGCAATTCGCTTCAGTTGGCGAATTACTGGGGGGGTCTTT
ATTGGCCGAAAAAGTGTTCGCCTATCCCGGTTTGGGGCAGGCGACGATTGATGCCGGGTTGCATGGTGACATTCCACTCT
TGATGGGAATAGTGATGTTCTGCGCCATATTGGTCTTTTGCGGTAATAGCATTGCGAATGCCTTGTTACACCGTTTGAAC
CGGGGGGCTGCGCGGCAATTATGA

Upstream 100 bases:

>100_bases
TCCAGCATACTTATCTGGCCAATAACTGCGTTGATTTAGGTAAAGGAACACCGGAAATTCACGGCTCCTGGTCATTGCTC
AATAGTATTGATAGCTGGAA

Downstream 100 bases:

>100_bases
CTTATAACCCAAACCGGGCCTTGTTCCGGCTGTTCGTCTCACTGGTCTTATTATCTATTTTAATCGTTTATGGTTGGCTA
ATTTATGGCGCTGAAGTTCC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDLSVMKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLDLPLWQRFLHWFTQVL
QGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLS
LFAVKLNWAPICCAWTPGSQAETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVN
FHILRHAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILVFCGNSIANALLHRLN
RGAARQL

Sequences:

>Translated_327_residues
MDLSVMKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLDLPLWQRFLHWFTQVL
QGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLS
LFAVKLNWAPICCAWTPGSQAETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVN
FHILRHAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILVFCGNSIANALLHRLN
RGAARQL
>Mature_327_residues
MDLSVMKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLDLPLWQRFLHWFTQVL
QGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLS
LFAVKLNWAPICCAWTPGSQAETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVN
FHILRHAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILVFCGNSIANALLHRLN
RGAARQL

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=307, Percent_Identity=31.9218241042345, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789965, Length=331, Percent_Identity=31.1178247734139, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=29.6416938110749, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=27.8810408921933, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789888, Length=302, Percent_Identity=26.4900662251656, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787761, Length=292, Percent_Identity=28.7671232876712, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788504, Length=267, Percent_Identity=22.8464419475655, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35780; Mature: 35780

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSVMKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAA
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCCCCCCCCCCCEEHH
RWGLDLPLWQRFLHWFTQVLQGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVG
HCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVKLNWAPICCAWTPGSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
AETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVN
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FHILRHAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
CAILVFCGNSIANALLHRLNRGAARQL
HHHHHHHCHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MDLSVMKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAA
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCCCCCCCCCCCEEHH
RWGLDLPLWQRFLHWFTQVLQGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVG
HCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVKLNWAPICCAWTPGSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
AETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVN
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FHILRHAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
CAILVFCGNSIANALLHRLNRGAARQL
HHHHHHHCHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA