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The map label for this gene is hha

Identifier: 22124953

GI number: 22124953

Start: 1179810

End: 1180013

Strand: Reverse

Name: hha

Synonym: y1046

Alternate gene names: 22124953

Gene position: 1180013-1179810 (Counterclockwise)

Preceding gene: 22124954

Following gene: 22124952

Centisome position: 25.65

GC content: 36.76

Gene sequence:

>204_bases
ATGACAAAAACTGACTACCTGATGCGTTTAAGAAAATGTACGACTATCGATACGCTAGAACGTGTAATTGAAAAAAATAA
GTACGAACTTTCTGATGATGAACTGGAATTGTTTTACTCAGCTGCAGACCATCGCCTGGCTGAACTAACGATGAATAAGC
TTTATGATAAAATTCCACCTACTGTATGGCAACATGTGAAATAG

Upstream 100 bases:

>100_bases
TTTATTCAGACTTTTCTCAGGGGAATACGTATGTACCCTGATGAAAACTTAAGGGATAGTTCCACCAATATTAATTTGTA
TATCGAGAAGAAAAACCACC

Downstream 100 bases:

>100_bases
TCTGCTTAGCGCTGGTTAAGACACACAACGTTGAGCCGATAATCTCTATCGGCTTCAATGGGTTTGATGATTAGCACGTG
TTTTAATTCTTAATAAAATT

Product: hemolysin expression-modulating protein

Products: NA

Alternate protein names: Histone-like protein

Number of amino acids: Translated: 67; Mature: 66

Protein sequence:

>67_residues
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPPTVWQHVK

Sequences:

>Translated_67_residues
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPPTVWQHVK
>Mature_66_residues
TKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPPTVWQHVK

Specific function: Modulates the thermoregulation of virF, and hence the yop regulon, as well as the expression of the enterotoxin gene yst. It is supposed to be involved in chromosome structure and DNA topology; probably by means of compaction of DNA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hha/ymoA/cnu family

Homologues:

Organism=Escherichia coli, GI1786665, Length=67, Percent_Identity=82.089552238806, Blast_Score=119, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YMOA_YEREN (P0A3X1)

Other databases:

- EMBL:   X58058
- PIR:   S15291
- ProteinModelPortal:   P0A3X1
- SMR:   P0A3X1
- InterPro:   IPR007985
- Gene3D:   G3DSA:1.20.1280.40

Pfam domain/function: PF05321 HHA; SSF68989 Haemolysin_expr_modulating

EC number: NA

Molecular weight: Translated: 8063; Mature: 7932

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPP
CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TVWQHVK
HHHHCCC
>Mature Secondary Structure 
TKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPP
CCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TVWQHVK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1956283; 1484495