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The map label for this gene is aroL [H]

Identifier: 22124879

GI number: 22124879

Start: 1097867

End: 1098391

Strand: Direct

Name: aroL [H]

Synonym: y0972

Alternate gene names: 22124879

Gene position: 1097867-1098391 (Clockwise)

Preceding gene: 22124878

Following gene: 22124880

Centisome position: 23.86

GC content: 49.9

Gene sequence:

>525_bases
ATGACACAAACTATCTTCATGGTAGGCGCGCGCGGTGCGGGTAAGACCACTATTGGGAAGGCATTGGCGCAGGCATTGGG
GTATCGGTTTGTTGATACAGATCTATTTATGCAACAAACCTCACAAATGACCGTGGCTGAAGTTGTTGAGAGTGAAGGTT
GGGATGGTTTTCGTCTACGTGAAAGCATGGCACTACAGGCAGTAACGGCACCTAAAACAGTCGTTGCCACTGGTGGTGGT
GCGGTACTGTCCAGTGAAAACCGCGCATTCATGCGTGATCATGGGCGAGTCATTTATCTGCGGGCGTCTGCAGCCGTATT
GGCAAAGCGGCTAGCGGAAGATCCTGAAGAGGCTCAGCGGCCAAGTTTAACCGGTAAACCCATCGTTGAAGAAATACTGG
ATGTGTTGGCTAGTCGTGAAGCGTTGTATCAGGACGTCGCCCATCATGTACTTGATGGAACGCAAACCCCGTCACTGGTT
GTCGAACAAATTTTACAGATGTTGACTGGTGAGATGGTCAAATAA

Upstream 100 bases:

>100_bases
TGAACCGCGTAGTAAACCTGTTCAACCGGCCAATAATAACGGTCGGTTTTTTGATGTCGAAAATTTATCCTCAGAAGTTG
ATACGAAGGACTTTCAAGTA

Downstream 100 bases:

>100_bases
TGAAGAAAAGGGGGGTTGATTGGTAATGTATGTAATGTGTGGAGCGAGTCTGGTTGATTGCTAATTAATTATGCAGGTAT
ACAATTGTCACCTACATAAT

Product: shikimate kinase II

Products: NA

Alternate protein names: SK 2 [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLRESMALQAVTAPKTVVATGGG
AVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQRPSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLV
VEQILQMLTGEMVK

Sequences:

>Translated_174_residues
MTQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLRESMALQAVTAPKTVVATGGG
AVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQRPSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLV
VEQILQMLTGEMVK
>Mature_173_residues
TQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLRESMALQAVTAPKTVVATGGGA
VLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQRPSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLVV
EQILQMLTGEMVK

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family. AroL subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=164, Percent_Identity=56.0975609756098, Blast_Score=196, Evalue=9e-52,
Organism=Escherichia coli, GI87082255, Length=169, Percent_Identity=36.6863905325444, Blast_Score=97, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=155, Percent_Identity=35.4838709677419, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18864; Mature: 18733

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLR
CCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ESMALQAVTAPKTVVATGGGAVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQR
HHHHHHHHCCCCEEEEECCCEEEECCCCHHHHCCCCEEEEECHHHHHHHHHHCCHHHHHC
PSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLVVEQILQMLTGEMVK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTIFMVGARGAGKTTIGKALAQALGYRFVDTDLFMQQTSQMTVAEVVESEGWDGFRLR
CCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ESMALQAVTAPKTVVATGGGAVLSSENRAFMRDHGRVIYLRASAAVLAKRLAEDPEEAQR
HHHHHHHHCCCCEEEEECCCEEEECCCCHHHHCCCCEEEEECHHHHHHHHHHCCHHHHHC
PSLTGKPIVEEILDVLASREALYQDVAHHVLDGTQTPSLVVEQILQMLTGEMVK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA